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Bidirectional causal relational between frailty and mental illness

A two-sample Mendelian randomization study

Datos Bibliográficos

ID15519702
AutoresLetian Ma (First Affiliated Hospital of Zhengzhou University), Zuying Liu (First Affiliated Hospital of Zhengzhou University), Lijun Fu (0000-0003-2501-3740, First Affiliated Hospital of Zhengzhou University), Jiaming Fan (0009-0001-0597-8310, First Affiliated Hospital of Zhengzhou University), Cunlong Kong (First Affiliated Hospital of Zhengzhou University), Tao Wang (0000-0002-8367-8946, First Affiliated Hospital of Zhengzhou University), Huilian Bu (0000-0002-0643-5692, First Affiliated Hospital of Zhengzhou University), Qingying Liu (0000-0002-5954-1958, First Affiliated Hospital of Zhengzhou University), Jingjing Yuan (0000-0002-3144-6123, First Affiliated Hospital of Zhengzhou University, autor de correspondencia), Xiaochong Fan (0000-0002-6640-2665, First Affiliated Hospital of Zhengzhou University, autor de correspondencia)
Año2024
Volumen15
Páginas1397813-1397813
Fecha de publicación2024-06-07
Peer ReviewedSí
Open AccessSí
TipoARTICLE
RevistaFrontiers in Psychiatry (JOURNAL)
Identificadores de la revistaISSN: 1664-0640 • E-ISSN: 1664-0640
EditorialFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2024.1397813
PMID38911707
OpenAlexW4399528519
IdiomaEN
Citas recibidas1
Referencias citadas60

The MR results suggest a potential bidirectional causal relationship between FI and anxiety, depression, and affective disorder. Schizophrenia was found to be associated with a higher risk of FI. The evidence was insufficient to support a causal relationship between Fl and other Ml. These findings offer new insights into the development of effective management strategies for frailty and MI

Anxiety · Biology · Bipolar disorder · Causality (physics · Confidence interval · Depression (economics · Genotype · Mania · Mendelian randomization · Mood · Observational study · Odds ratio · Psychiatry · Schizophrenia (object-oriented programming · Clinical Psychology · Frailty in Older Adults · Health Systems, Economic Evaluations, Quality of Life · Medicine · Nutrition and Health in Aging · Genetics · Internal Medicine

  • Dual trajectories of social participation and frailty in Chinese older adults

    Open Access•Yiyun Bi, Jing Hu et al.•Frontiers in Public Health•2024

  • Frailty

    Open Access•Emiel O Hoogendijk, Jonathan Afilalo et al.•The Lancet•2019

  • Mortality in Mental Disorders and Global Disease Burden Implications

    Elizabeth Reisinger Walker, Robin E Mcgee et al.•JAMA Psychiatry•2015

  • Mendelian randomization with invalid instruments

    Open Access•Jack Bowden, Gregory D Smith et al.•International Journal of…•2015

  • ‘Mendelian randomization’

    Gregory D Smith, Shah Ebrahim•International Journal of…•2003

  • Frailty in elderly people

    Open Access•Andrew Clegg, John Young et al.•The Lancet•2013

  • Mapping genomic loci implicates genes and synaptic biology in schizophrenia

    Open Access•Vassily Trubetskoy, Antonio F Pardiñas et al.•Nature•2022

  • The future of mental health care

    Open Access•John A Naslund, Kelly A Aschbrenner et al.•Epidemiology and Psychiatric…•2016

  • The causal role of gastroesophageal reflux disease in anxiety disorders and depression

    Open Access•Youjie Zeng, Si Cao et al.•Frontiers in Psychiatry•2023

  • Frailty among inpatients with Schizophrenia

    Open Access•Cui Yang, Xiaofeng Hou et al.•Frontiers in Psychiatry•2023

  • Accelerated Brain Aging in Patients With Obsessive-Compulsive Disorder

    Open Access•Liang Liu, Junhong Liu et al.•Frontiers in Psychiatry•2022

  • Frailty as a Moderator of the Relationship between Social Isolation and Health Outcomes in Community-Dwelling Older Adults

    Open Access•Fereshteh Mehrabi, Francois Beland•International Journal of…•2021

  • Association between frailty and quality of life among community-dwelling older people

    Gotaro Kojima, Steve Iliffe et al.•Journal of Epidemiology and…•2016

  • Frailty and Treatment-Resistant Schizophrenia

    Open Access•Ella Pearson, Dan Siskind et al.•Community Mental Health Journal•2022

Obras citantes distintas1
Citas por año0,5
Intervalo de citas2024 - 2024 (1)
Velocidad de citaciónrecent
Altamente citadoNo
Tipos de citaNeutras: 1
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