Causal relationship between depression and metabolic dysfunction-associated steatotic liver disease

A bidirectional Mendelian randomized study

Datos Bibliográficos

ID15520669
AutoresWeiyu Liang (Guangzhou University of Chinese Medicine), Kunting Zhong (Guangzhou University of Chinese Medicine), Tingting Lai (0000-0002-9045-5476, Guangzhou University of Chinese Medicine), Yuhao Zeng (0000-0001-9931-6221, Guangzhou University of Chinese Medicine), Zhanhui Huang (0000-0002-9294-3924), Jiqing Zhou (Guangzhou University of Chinese Medicine), Jin Huang (0000-0002-2833-8041, Guangzhou University of Chinese Medicine), Zhenni Shi (Guangzhou University of Chinese Medicine), Jin Zhang (0000-0002-1374-598X, Guangzhou University of Chinese Medicine, autor de correspondencia), Fuping Ding (0000-0002-3445-8912, Guangzhou University of Chinese Medicine, autor de correspondencia)
Año2024
Volumen15
Páginas1384003-1384003
Fecha de publicación2024-06-06
Peer ReviewedSí
Open AccessSí
TipoARTICLE
RevistaFrontiers in Psychiatry (JOURNAL)
Identificadores de la revistaISSN: 1664-0640 • E-ISSN: 1664-0640
EditorialFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2024.1384003
PMID38903646
OpenAlexW4399523549
IdiomaEN
Citas recibidas1
Referencias citadas13

The MR analysis revealed a positive causal relationship between depression and MASLD, while no reverse causal relationship was identified. Liver enzymes may mediate the role between depression and MASLD

Biology · Depression (economics · Gene · Genome-wide association study · Genotype · Mendelian randomization · Single-nucleotide polymorphism · Genetic Associations and Epidemiology · Hepatitis C virus research · Liver Disease Diagnosis and Treatment · Medicine · Endocrinology · Genetics · Internal Medicine