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Examining putamen resting-state connectivity markers of suicide attempt history in depressed adolescents

Datos Bibliográficos

ID15523514
AutoresOlga Tymofiyeva (0000-0003-2589-1041, University of California, San Francisco, autor de correspondencia), Tiffany C Ho (0000-0002-4500-6364, University of California, Los Angeles), Colm G Connolly (0000-0002-4051-3682, Florida State University), Sasha Gorrell (0000-0002-8861-8547, University of California, San Francisco), Ryan Rampersaud (0000-0003-4718-0267, University of California, San Francisco), Sabrina M Darrow (0000-0002-5639-0285, University of California, San Francisco), Jeffrey E Max (0000-0002-6566-1585, Rady Children's Hospital-San Diego), Tony T Yang (0000-0003-2727-9438, University of California, San Francisco)
Año2024
Volumen15
Páginas1364271-1364271
Fecha de publicación2024-06-06
Open AccessSí
TipoARTICLE
RevistaFrontiers in Psychiatry (JOURNAL)
Identificadores de la revistaISSN: 1664-0640 • E-ISSN: 1664-0640
EditorialFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2024.1364271
PMID38903634
OpenAlexW4399524030
IdiomaEN
Citas recibidas1
Referencias citadas64

The results align with recent adult literature and have interesting theoretical and clinical implications. A possible interpretation of the results is a mismatch of the serotonin transport to putamen and to the supplementary motor area and the resulting reduced functional connectivity between the two areas in adolescents with attempt history. The obtained results can be used to enhance the diathesis-stress model and the Emotional paiN and social Disconnect (END) model of adolescent suicidality by adding the putamen. We also speculate that connectivity between putamen and the supplementary motor area may in the future be used as a valuable biomarker of treatment efficacy and possibly prediction of treatment outcome

Depression (economics · Injury prevention · Poison control · Psychiatry · Putamen · Serotonergic · Serotonin · Striatum · Suicidal ideation · Ventral striatum · Advanced Neuroimaging Techniques and Applications · Clinical Psychology · Functional Brain Connectivity Studies · Medicine · Mental Health Research Topics · Neuroscience · Psychology · Internal Medicine

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Citas por año1
Intervalo de citas2025 - 2025 (1)
Altamente citadoNo
Abrir DOIOpen Access
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