Efficacy of an Internet-Based Intervention for Subclinical Depression (MoodBox) in China

Study Protocol for a Randomized Controlled Trial

Datos Bibliográficos

ID15529397
AutoresXu Chen (0000-0002-8164-3088), Chen Xu (0000-0002-5225-5350, Beijing Anding Hospital), Xiaolong Zhang (0000-0002-0417-0002, Capital Medical University), Xuequan Zhu (0000-0001-5551-2810, Capital Medical University), Gang Wang (0000-0002-2288-3807, Capital Medical University, autor de correspondencia)
Año2021
Volumen11
Páginas585920-585920
Fecha de publicación2021-01-12
Peer ReviewedSí
Open AccessSí
TipoARTICLE
RevistaFrontiers in Psychiatry (JOURNAL)
Identificadores de la revistaISSN: 1664-0640 • E-ISSN: 1664-0640
EditorialFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2020.585920
PMID33510658
OpenAlexW3118482415
IdiomaEN
Referencias citadas33

Background: Subclinical depression is a prevalent mental health problem and increases the incidence of the onset of major mood disorders, such as major depressive disorder (MDD). Psychological interventions have been proved to be effective for reducing depressive symptoms for people with subclinical depression and can prevent the onset of MDD. However, people have limited access to face-to-face psychotherapy. Internet-based psychological intervention is an alternative treatment option. The aim of the study is to evaluate the efficacy of MoodBox, an online psychological intervention program, for subclinical depression. Methods: This study is a multicenter, randomized, controlled, non-blinded superiority study with three parallel groups. A total of 435 first-year university students with subclinical depression will be recruited. Eligible participants will be randomly assigned to the MoodBox group, the online psychoeducation group, and the naturalistic observation group at a ratio of 1:1:1. The intervention period is 8 weeks, and participants will be continuously followed up for 1 year. The primary outcome of the study is the efficacy of the intervention, defined as measured by the Patient Health Questionnaire (PHQ-9). Discussion: This is the first study to innovatively develop and test an intervention to improve psychological well-being and decrease the incidence of MDD in a subclinical depression population in China. Once proven effective and acceptable, MoodBox could be potentially integrated into the routine clinical service to facilitate the management for people with subclinical depression. Clinical Trial Registration: The trial is registered with the Chinese Clinical Trial Registry on 21 July 2020 (No. ChiCTR2000034826)

Anxiety · Clinical trial · Depression (economics · Depressive symptoms · Intervention (counseling · Major depressive disorder · Mood · Patient Health Questionnaire · Physical therapy · Population · Psychiatry · Psychoeducation · Psychological intervention · Psychosocial · Randomized controlled trial · Subclinical infection · Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes · Clinical Psychology · Digital Mental Health Interventions · Medicine · Mental Health Research Topics · Internal Medicine