Resistencia antimicrobiana de uropatógenos en adultos mayores de una clínica privada de Lima, Perú

Datos Bibliográficos

ID15533741
AutoresJacqueline Miranda (0000-0002-3715-6442, autor de correspondencia), Joseph A Pinto (0000-0002-7744-1635, Universidad Privada San Juan Bautista), Joseph Pinto, Margot Faustino (Universidad Peruana Cayetano Heredia), Billy J Sánchez-Jacinto (0000-0001-7106-4114, Universidad Peruana Cayetano Heredia), Billy Sánchez-Jacinto, Fabrizio Delissalde Ramirez (Universidad Privada San Juan Bautista), Fabrizio Ramirez
Año2019
Volumen36
Número1
Páginas87-87
Fecha de publicación2019-03-22
Peer ReviewedSí
Open AccessSí
TipoARTICLE
RevistaRevista Peruana de Medicina Experimental y Salud Pública (JOURNAL)
Identificadores de la revistaISSN: 1726-4634 • E-ISSN: 1726-4642
EditorialNational Institute of Health of Peru (PUBLISHER • PE)
DOI10.17843/rpmesp.2019.361.3765
PMID31116345
OpenAlexW2922867425
IdiomaES
Citas recibidas2
Referencias citadas1

The main mechanisms of antimicrobial resistance are described using the Vitek® 2 system in uropathogens isolated in older adults from a private clinic in Lima. Descriptive study conducted between January 2014 and October 2016. Escherichia coli, Klebsiella pneumoniae, and Proteus mirabilis obtained a sensitivity greater than 80% against piperacillin/ tazobactam, amikacin, and carbapenems. Moreover, 83.6% of Escherichia coli were nitrofurantoin-sensitive strains. A 41.7% of Escherichia coli, 50.9% of Klebsiella pneumoniae, and 50% of Proteus mirabilis were producers of extended spectrum beta-lactamases (ESBL). Similarly, 60% of Pseudomonas aeruginosa were producers of carbapenemases. Active site modification (PBP) and enzymatic inactivation by penicillinases occurred in 7.8% of Enterococcus faecalis. Resistance to aminoglycosides was presented in Escherichia coli (27.1%), Klebsiella pneumoniae (46.7%), and Proteus mirabilis (84.6%) for the production of modifier enzymes. There is an increase in bacterial resistance in relation to age. Enzymatic inactivation of beta-lactam antibiotics and aminoglycosides is the most common resistance mechanism

Aspergillosis · Aspergillus · Aspergillus fumigatus · Biology · Gene · Polymerase chain reaction · Antifungal resistance and susceptibility · Genetics · Immunology · Microbiology · Molecular Biology