Effectiveness of lipid‐based nutrient supplementation during the first 1000 days of life for early childhood development
A community‐based trial from Pakistan
Datos Bibliográficos
| ID | 15536717 |
|---|---|
| Autores | Ayesha Imtiaz (0000-0002-2643-6879, Khyber Medical University), Zia Ul Haq (0000-0002-2518-3451, Institute of Public Health & Social Sciences Khyber Medical University Peshawar Pakistan), Zia Ul-Haq (0000-0001-5124-2171, Khyber Medical University), Suhail A R Doi (0000-0002-2630-2125, Qatar University), Sheraz Fazid (0000-0002-0096-928X, Khyber Medical University), Muhammad Naseem Khan (0000-0002-0484-0985, Qatar University, autor de correspondencia) |
| Año | 2024 |
| Volumen | 21 |
| Número | 1 |
| Páginas | e13727-e13727 |
| Fecha de publicación | 2024-09-24 |
| Peer Reviewed | Sí |
| Open Access | Sí |
| Tipo | ARTICLE |
| Revista | Maternal and Child Nutrition (JOURNAL) |
| Identificadores de la revista | ISSN: 1740-8695 • E-ISSN: 1740-8709 |
| Editorial | Wiley (PUBLISHER • GB) |
| DOI | 10.1111/mcn.13727 |
| PMID | 39318197 |
| OpenAlex | W4402843952 |
| Idioma | EN |
| Referencias citadas | 36 |
A community-based, cluster non-randomized controlled trial was conducted in Kurram district, Pakistan between January 2018 to December 2020. Age-appropriate lipid-based nutrient supplements and health education (sessions conducted in the households) were given to pregnant women and their born children (6-23 months) in the intervention arm (n = 40 clusters) versus health education only in the control arm (n = 40 clusters) to evaluate its effect on child development. The first and second developmental assessments were completed at ~24 months (n = 689) and ~32 months (n = 608), respectively, using the Caregiver-Reported Early Development Instrument Long form. The overall and domain-specific (motor, language, cognitive and socio-emotional) scores were computed with higher scores indicating better child development. Higher development scores, including overall (β = 0.40, 95% confidence interval [CI]: 0.14, 0.65; p = 0.002), cognitive (β = 0.27, 95% CI: 0.10, 0.45; p = 0.002), motor (β = 0.39, 95% CI: 0.22, 0.56; p < 0.001) and language (β = 0.33, 95% CI: 0.14, 0.51; p = 0.001) were reported for children who received the intervention compared to the control arm at first developmental assessment. However, the effect was not sustained after the discontinuation of the intervention. The LNS received by the mothers (during pregnancy and first 6 months after delivery) and by children during 6-23 months of age was beneficial for the children. The trial is registered in the International Standard Randomised Controlled Trial Number Registry (ID: ISRCTN94319790) on December 11, 2017
Child development · Cluster randomised controlled trial · Confidence interval · Discontinuation · Early childhood · Intervention (counseling · Pregnancy · Psychiatry · Randomized controlled trial · Birth, Development, and Health · Child Nutrition and Water Access · Infant Development and Preterm Care · Medicine · Internal Medicine · Pediatrics
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The social determinants of early child development
Consort 2010 statement
Nutrition and brain development in early life
Characteristics and effects of integrated nutrition and stimulation interventions to improve the nutritional status and development of children under 5 years of age
Validation of motor, cognitive, language, and socio-emotional subscales using the Caregiver Reported Early Development Instruments
Effects of lipid-based nutrient supplements v . micronutrient powders on nutritional and developmental outcomes among Peruvian infants
Small-quantity lipid-based nutrient supplements for children age 6–24 months
Measuring early childhood development at a global scale
| Velocidad de citación | historical |
|---|---|
| Altamente citado | No |