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The Approach to a Child with Dysmorphic Features

What the Pediatrician Should Know

Datos Bibliográficos

ID15718596
AutoresSilvia Ciancia (0000-0003-0874-4648, University of Modena and Reggio Emilia), Simona Filomena Madeo (University of Modena and Reggio Emilia), Olga Calabrese (0000-0001-8947-5990, University of Modena and Reggio Emilia), Lorenzo Iughetti (0000-0003-0370-7872, University of Modena and Reggio Emilia, autor de correspondencia)
Año2024
Volumen11
Número5
Páginas578-578
Fecha de publicación2024-05-10
Peer ReviewedSí
Open AccessSí
TipoARTICLE
RevistaChildren (JOURNAL)
Identificadores de la revistaISSN: 2227-9067 • E-ISSN: 2227-9067
EditorialMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/children11050578
PMID38790573
OpenAlexW4396888486
IdiomaEN
Referencias citadas83

The advancement of genetic knowledge and the discovery of an increasing number of genetic disorders has made the role of the geneticist progressively more complex and fundamental. However, most genetic disorders present during childhood; thus, their early recognition is a challenge for the pediatrician, who will be also involved in the follow-up of these children, often establishing a close relationship with them and their families and becoming a referral figure. In this review, we aim to provide the pediatrician with a general knowledge of the approach to treating a child with a genetic syndrome associated with dysmorphic features. We will discuss the red flags, the most common manifestations, the analytic collection of the family and personal medical history, and the signs that should alert the pediatrician during the physical examination. We will offer an overview of the physical malformations most commonly associated with genetic defects and the way to describe dysmorphic facial features. We will provide hints about some tools that can support the pediatrician in clinical practice and that also represent a useful educational resource, either online or through apps downloaded on a smartphone. Eventually, we will offer an overview of genetic testing, the ethical considerations, the consequences of incidental findings, and the main indications and limitations of the principal technologies

Family medicine · Genetic counseling · Genetic testing · Geneticist · Psychiatry · Referral · Resource (disambiguation · Computer Science · Genomic variations and chromosomal abnormalities · Genomics and Rare Diseases · Medicine · Psychology · Tumors and Oncological Cases · Genetics · Pediatrics

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