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Apple pomace extract

Photochemopreventive action against UVA radiation in a cell culture model

Datos Bibliográficos

ID16891069
AutoresRodrigo Molina Martins (0000-0001-7982-3429, autor de correspondencia), Silvia de Siqueira Martins, Gustavo Luis Ferreira Barbosa (0000-0003-0519-3844), Denilson Leal Rocha (0000-0003-4005-1497), Samantha Mayara de Sousa Silva, Thamara Rodrigues de Melo (0000-0001-6540-9585), Luis Alexandre Pedro de Freitas (0000-0002-6561-4711), Maria José Vieira Fonseca (0000-0002-7123-4838)
Año2024
Volumen16
Número5
Páginase4221
Fecha de publicación2024-05-17
Open AccessSí
TipoARTICLE
RevistaCuadernos de Educación y Desarrollo (JOURNAL)
Identificadores de la revistaISSN: 1989-4155 • E-ISSN: 1989-4155
EditorialBrazilian Journals (PUBLISHER)
DOI10.55905/cuadv16n5-064
OpenAlexW4397031959
IdiomaEN
Referencias citadas23

Apple pomace, a byproduct from juice industry, can be used as a valuable nutraceutical, hence its phenolic compounds, including rutin, are powerful antioxidants. This work evidence the extract enriched with apple polyphenols from apple pomace using ethanol: water as solvent and partitioned with ethyl acetate (1:1 w/w), where its lyophilized product was evaluated for its photochemopreventive action on MRC-5 fibroblasts against a harmful UVA radiation dose. The enriched apple pomace extract was able to promote photochemopreventive action against UVA radiation, decreasing cell death and the lipid peroxidation formation. Therefore, the optimized extraction process may make the apple pomace application viable as a source of bioactive extracts with photochemopreventive action against ultraviolet radiation to the use in dermal formulations

Physics · Pomace · Chemistry · Essential Oils and Antimicrobial Activity · Light effects on plants · Phytochemicals and Antioxidant Activities · Food Science

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