Adolescent Obesity and Risk for Subsequent Major Depressive Disorder and Anxiety Disorder

Prospective Evidence

Datos Bibliográficos

ID19306338
AutoresSarah Anderson (0000-0002-8581-1544, Health and Human Development (2HD) Research Network, autor de correspondencia), Sarah E Anderson (0000-0002-7522-2340), Patricia Cohen (Columbia University), Elena N Naumova (0000-0002-9562-4734, National Institute of Diabetes and Digestive and Kidney Diseases), Paul F Jacques (0000-0001-5567-3147, Tufts University), Aviva Must (0000-0002-6456-3174, Health and Human Development (2HD) Research Network)
Año2007
Volumen69
Número8
Páginas740-747
Fecha de publicación2007-10-01
Peer ReviewedSí
Open AccessNo
TipoARTICLE
RevistaPsychosomatic Medicine (JOURNAL)
Identificadores de la revistaISSN: 0033-3174 • E-ISSN: 1534-7796
EditorialOvid Technologies (Wolters Kluwer Health) (PUBLISHER)
DOI10.1097/psy.0b013e31815580b4
PMID17942847
OpenAlexW2036285824
IdiomaEN
Citas recibidas25
Referencias citadas41

Objective: To assess whether adolescent obesity is associated with risk for development of major depressive disorder (MDD) or anxiety disorder. Obesity has been linked to psychosocial difficulties among youth. Methods: Analysis of a prospective community-based cohort originally from upstate New York, assessed four times over 20 years. Participants (n = 776) were 9 to 18 years old in 1983; subsequent assessments took place in 1985 to 1986 (n = 775), 1991 to 1994 (n = 776), and 2001 to 2003 (n = 661). Using Cox proportional hazards analysis, we evaluated the association of adolescent (age range, 12–17.99 years) weight status with risk for subsequent MDD or anxiety disorder (assessed at each wave by structured diagnostic interviews) in males and females. A total of 701 participants were not missing data on adolescent weight status and had ≥1 subsequent assessments. MDD and anxiety disorder analyses included 674 and 559 participants (free of current or previous MDD or anxiety disorder), respectively. Adolescent obesity was defined as body mass index above the age- and gender-specific 95th percentile of the Centers for Disease Control and Prevention growth reference. Results: Adolescent obesity in females predicted an increased risk for subsequent MDD (adjusted hazard ratio (HR) = 3.9; 95% confidence interval (CI) = 1.3, 11.8) and for anxiety disorder (HR = 3.8; CI = 1.3, 11.3). Adolescent obesity in males was not statistically significantly associated with risk for MDD (HR = 1.5; CI = 0.5, 3.5) or anxiety disorder (HR = 0.7; CI = 0.2, 2.9). Conclusion: Females obese as adolescents may be at increased risk for development of depression or anxiety disorders. BMI = body mass index; CDC = Centers for Disease Control and Prevention; CI = confidence interval; CIC = Children in the Community Study; DSM = Diagnostic and Statistical Manual of Mental Disorders; DISC = Diagnostic Interview Schedule for Children; HR = hazard ratio; SCID-IV = Structured Clinical Interview for DSM-IV Disorders; SD = standard deviation; SES = socioeconomic status

Anxiety · Anxiety disorder · Body mass index · Cohort · Confidence interval · Generalized anxiety disorder · Hazard ratio · Major depressive disorder · Mood · Obesity · Proportional hazards model · Prospective cohort study · Psychiatry · Psychosocial · Child and Adolescent Psychosocial and Emotional Development · Eating Disorders and Behaviors · Internal Medicine · Medicine · Obesity, Physical Activity, Diet · Psychology