Sleep Disturbance as a Mediator of Lung Cancer Stigma on Psychological Distress and Physical Symptom Burden

Datos Bibliográficos

ID19306348
AutoresTimothy J Williamson (0000-0002-3678-0657, Angeles University Foundation, autor de correspondencia), Edward B Garon (0000-0001-7077-8801, Angeles University Foundation), Michael R Irwin (0000-0002-1502-8431, Angeles University Foundation), Alyssa K Choi (0000-0002-2389-8533, Angeles University Foundation), Jonathan W Goldman (0000-0002-4925-8243, Angeles University Foundation), Annette L Stanton (0000-0001-9021-2549, Angeles University Foundation)
Año2024
Volumen86
Número4
Páginas334-341
Fecha de publicación2024-05-01
Peer ReviewedSí
Open AccessNo
TipoARTICLE
RevistaPsychosomatic Medicine (JOURNAL)
Identificadores de la revistaISSN: 0033-3174 • E-ISSN: 1534-7796
EditorialOvid Technologies (Wolters Kluwer Health) (PUBLISHER)
DOI10.1097/psy.0000000000001299
PMID38436657
OpenAlexW4392368943
IdiomaEN
Citas recibidas1
Referencias citadas66

OBJECTIVE: This study tested sleep disturbance as a mediator through which stigma and discrimination predict psychological distress and physical symptom burden in adults with lung cancer. METHODS: Lung cancer patients on active oncological treatment ( N = 108; 74.1% stage IV) completed questionnaires on lung cancer stigma, sleep, distress, and physical symptoms at study entry and at 6- and 12-week follow-up. Mediation analyses were conducted to investigate whether stigma and discrimination predicted distress and physical symptoms at study entry and across 12 weeks through disrupted sleep. RESULTS: Higher discrimination ( b = 5.52, 95% confidence interval [CI] = 2.10-8.94) and constrained disclosure ( b = 0.45, 95% CI = 0.05-0.85) were associated significantly with higher sleep disruption at study entry. Sleep disruption, in turn, was associated with higher distress ( b = 0.19, 95% CI = 0.09-0.29) and physical symptoms ( b = 0.28, 95% CI = 0.17-0.40) at study entry. Sleep disruption significantly mediated relationships between higher discrimination and the outcomes of distress (indirect effect = 1.04, 95% CI = 0.13-1.96) and physical symptoms (indirect effect = 1.58, 95% CI = 0.37-2.79) at study entry. Sleep disruption also mediated relationships between constrained disclosure and the outcomes of distress (indirect effect = 0.85, 95% CI = < 0.01-0.17) and physical symptoms (indirect effect = 0.13, 95% CI = 0.01-0.25). CONCLUSIONS: Lung cancer patients evidenced pronounced sleep disruption, which mediated relationships between indicators of lung cancer stigma and distress and physical symptoms at study entry. Research is needed to test additional mechanisms through which lung cancer stigma predicts these outcomes longitudinally

Anxiety · Distress · Human immunodeficiency virus (HIV) · Insomnia · Lung cancer · Mediator · Psychiatry · Psychological distress · Psychotherapist · Sleep (system call) · Sleep disorder · Social stigma · Stigma (botany) · Cancer survivorship and care · Clinical Psychology · Global Cancer Incidence and Screening · Internal Medicine · Medicine · Oncology · Psychology · Sleep and related disorders