General and abdominal obesity and incident hypertension among people living with HIV on antiretroviral therapy

Datos Bibliográficos

ID19444366
AutoresXiaohui Xu (0000-0002-6604-268X, Fudan University), Xiaoxiao Chen (0009-0009-8655-4920, Taizhou City Center for Disease Control and Prevention, Taizhou City, People’s Republic of China), Haijiang Lin (0000-0002-4550-0258, Taizhou City Center for Disease Control and Prevention, Taizhou City, People’s Republic of China), Bowen Zhu (0009-0004-1791-1107, Fudan University), Weiwei Shen (0000-0002-6893-5158, Taizhou City Center for Disease Control and Prevention, Taizhou City, People’s Republic of China), Ruizi Shi (0000-0002-0546-9348, Fudan University), Xiaoyi Xu (0000-0001-8432-6291, Fudan University), Na He (0000-0003-4347-7899, Fudan University), Yingying Ding (0000-0001-6533-8035, Fudan University, autor de correspondencia)
Año2021
Volumen33
Número12
Páginas1616-1620
Fecha de publicación2021-12-02
Peer ReviewedSí
Open AccessNo
TipoARTICLE
RevistaAIDS Care (JOURNAL)
Identificadores de la revistaISSN: 0954-0121 • E-ISSN: 1360-0451
EditorialInforma UK Limited (PUBLISHER • GB)
DOI10.1080/09540121.2020.1852158
PMID33269606
OpenAlexW3106896658
IdiomaEN
Referencias citadas21

Hypertension is highly prevalent among people living with HIV (PLWH). We sought to characterize the hypertension incidence among PLWH on antiretroviral therapy, focusing on the effect of change in general and abdominal obesity on hypertension during follow-up. This was a prospective analysis of 229 treated PLWH aged over 40 years without hypertension at baseline. Overall a median follow-up of 2.9 years, 26.2% PLWH developed hypertension. In multivariable models, compared to those without obesity measures at both baseline and follow-up visit, PLWH with general obesity at both occasions (adjusted odds ratio [aOR] = 3.83, P = 0.006) or at baseline only (aOR = 5.45, P = 0.003), abdominal obesity (measured as waist circumference) at both occasions (aOR = 3.87, P = 0.001) or at follow-up only (aOR = 2.27; 9P = 0.060), abdominal obesity (measured as waist-to-hip ratio) at both occasions (aOR = 2.27, P = 0.077) were at increased risk of incident hypertension. Our data show that both general and abdominal obesity especially in the persistent status increase the hypertension risk in treated PLWH

Abdominal obesity · Antiretroviral therapy · Body mass index · Obesity · Odds ratio · Prospective cohort study · Viral load · Waist · HIV-related health complications and treatments · HIV/AIDS drug development and treatment · HIV/AIDS Research and Interventions · Medicine · Internal Medicine