Differentiated care for youth in Zimbabwe

Outcomes across the HIV care cascade

Datos Bibliográficos

ID19590657
AutoresChido Dziva Chikwari (0000-0003-1617-3603, London School of Hygiene & Tropical Medicine, autor de correspondencia), Katharina Kranzer (0000-0001-5691-7270, London School of Hygiene & Tropical Medicine, autor de correspondencia), Victoria Simms (0000-0001-5664-6810, London School of Hygiene & Tropical Medicine, autor de correspondencia), Amani Patel (0000-0003-0580-0288, London School of Hygiene & Tropical Medicine, autor de correspondencia), Mandikudza Tembo (0000-0002-4520-3317, London School of Hygiene & Tropical Medicine, autor de correspondencia), Owen Mugurungi (0000-0001-7779-5583, Ministry of Health and Child Welfare, autor de correspondencia), Edwin Sibanda (Mpilo Central Hospital, autor de correspondencia), Onismo Mufare (Biomedical Research and Training Institute, autor de correspondencia), Lilian Ndlovu (Biomedical Research and Training Institute, autor de correspondencia), Joice Muzangwa (Biomedical Research and Training Institute, autor de correspondencia), Rumbidzayi Vundla (Biomedical Research and Training Institute, autor de correspondencia), Abigail Chibaya (Biomedical Research and Training Institute, autor de correspondencia), Renée Hayes (0000-0002-1729-9892, London School of Hygiene & Tropical Medicine, autor de correspondencia), Constance R Smackworth-Young (0000-0002-9725-7931, London School of Hygiene & Tropical Medicine, autor de correspondencia), Constance Mackworth-Young, Bernay (0000-0001-7628-8408, The University of Sydney, autor de correspondencia), Constancia Vimbayi Mavodza (0000-0003-1651-5888, London School of Hygiene & Tropical Medicine, autor de correspondencia), Constancia Mavodza, Fadzanayi Hove (Biomedical Research and Training Institute, autor de correspondencia), Tsitsi Bandason (0000-0003-0066-8345, Biomedical Research and Training Institute, autor de correspondencia), Ethel Dauya (0000-0003-3241-2512, Biomedical Research and Training Institute, autor de correspondencia), Rashida A Ferrand (0000-0002-7660-9176, London School of Hygiene & Tropical Medicine, autor de correspondencia)
EditoresJohn M Francis (0000-0003-1902-2683)
Año2024
Volumen4
Número2
Páginase0002553
Fecha de publicación2024-02-21
Peer ReviewedSí
Open AccessSí
TipoARTICLE
RevistaPLOS Global Public Health (JOURNAL)
Identificadores de la revistaISSN: 2767-3375 • E-ISSN: 2767-3375
EditorialPublic Library of Science (PLoS) (PUBLISHER)
DOI10.1371/journal.pgph.0002553
PMID38381752
OpenAlexW4391993797
IdiomaEN
Referencias citadas26

Youth living with HIV are at higher risk than adults of disengaging from HIV care. Differentiated models of care such as community delivery of antiretroviral therapy (ART) may improve treatment outcomes. We investigated outcomes across the HIV cascade among youth accessing HIV services in a community-based setting. This study was nested in a cluster-randomised controlled trial (CHIEDZA: Clinicaltrials.gov, Registration Number: NCT03719521) conducted in three provinces in Zimbabwe and aimed to investigate the impact of a youth-friendly community-based package of HIV services, integrated with sexual and reproductive health services for youth (16–24 years), on population-level HIV viral load (VL). HIV services included HIV testing, ART initiation and continuous care, VL testing, and adherence support. Overall 377 clients were newly diagnosed with HIV at CHIEDZA, and linkage to HIV care was confirmed for 265 (70.7%, 234 accessed care at CHIEDZA and 31 with other providers); of these 250 (94.3%) started ART. Among those starting ART at CHIEDZA who did not transfer out and had enough follow up time (>6 months), 38% (68/177) were lost-to-follow-up within six months. Viral suppression (HIV Viral Load

Antiretroviral therapy · Environmental health · Family medicine · Health care · Population · Viral load · Adolescent Sexual and Reproductive Health · HIV, Drug Use, Sexual Risk · HIV/AIDS Research and Interventions · Medicine · Gerontology