Multi-omics integrated analyses indicated that non-polysaccharides of Sijunzi decoction ameliorated spleen deficiency syndrome via regulating microbiota-gut-metabolites axis and exerted synergistic compatibility
Datos Bibliográficos
| ID | 21095010 |
|---|---|
| Autores | Bangjian Dong (0009-0007-8027-3103, Shanghai Jiao Tong University), Ying Peng (0000-0002-8801-5711, Shanghai Jiao Tong University), Mengyue Wang (0000-0002-3839-758X, Shanghai Jiao Tong University), Chongsheng Peng (0009-0009-8031-6163, Shanghai Jiao Tong University), Xiaobo Li (0000-0002-2752-749X, Shanghai Jiao Tong University, autor de correspondencia) |
| Año | 2024 |
| Volumen | 331 |
| Páginas | 118276 |
| Fecha de publicación | 2024-09-01 |
| Peer Reviewed | Sí |
| Open Access | Sí |
| Tipo | ARTICLE |
| Revista | Journal of Ethnopharmacology (JOURNAL) |
| Identificadores de la revista | ISSN: 0378-8741 • E-ISSN: 1872-7573 |
| Editorial | Elsevier BV (PUBLISHER) |
| DOI | 10.1016/j.jep.2024.118276 |
| PMID | 38697408 |
| OpenAlex | W4396559902 |
| Idioma | EN |
| Citas recibidas | 6 |
| Referencias citadas | 71 |
Bioinformatics · Biology · Decoction · Gut flora · Metabolome · Metabolomics · Microbiome · Spleen · Traditional Chinese medicine · Traditional medicine · Chemistry · Dietary Effects on Health · Ginseng Biological Effects and Applications · Gut microbiota and health · Medicine · Biochemistry · Immunology · Pharmacology
Integrated metabolomics and proteomics revealed the comprehensive mechanism of Sijunzi decoction and its active components in improving multi-system dysfunction induced by spleen deficiency syndrome
The Central Qi theory in traditional Chinese medicine
Oligosaccharides and small molecule components of Sijunzi decoction modulate the gut microbiota-bile acid axis to synergistically alleviate spleen deficiency syndrome
Shen Ling Bai Zhu San promotes gut IgA+ plasma cells to alleviate chronic diarrhea in mice via increasing systematic glutamine
Rhizome of Atractylodes macrocephala alleviates spleen-deficiency constipation in rats by modulating gut microbiota and bile acid metabolism
Sijunzi Decoction treatment improved depression with qi deficiency/fatigue in the strain-dependent manner, involved in anti-inflammation in the hippocampus and muscles
Dissection of mechanisms of Chinese medicinal formula Realgar- Indigo naturalis as an effective treatment for promyelocytic leukemia
Drug-polysaccharide/herb interactions and compatibility rationality of Sijunzi decoction based on comprehensive pharmacokinetic screening for multi-components in rats with spleen deficiency syndrome
Effects of a homogeneous polysaccharide from Sijunzi decoction on human intestinal microbes and short chain fatty acids in vitro
The pharmacokinetic profiles of mogrosides in T2DM rats
Mechanisms of traditional Chinese medicine in modulating gut microbiota metabolites-mediated lipid metabolism
The compatibility rationality of Sijunzi decoction based on integrated analysis of tissue distribution and excretion characteristics in spleen deficiency syndrome rats
Recent pharmaceutical evidence on the compatibility rationality of traditional Chinese medicine
Integrating metabolomics and network pharmacology to reveal the mechanisms of Delphinium brunonianum extract against nonalcoholic steatohepatitis
A mechanism of Sijunzi decoction on improving intestinal injury with spleen deficiency syndrome and the rationality of its compatibility
The water extract of Radix scutellariae, its total flavonoids and baicalin inhibited CYP7A1 expression, improved bile acid, and glycolipid metabolism in T2DM mice
Effective substances and mechanism of red ginseng on rats with spleen-deficiency syndrome based on the substance and energy metabolism as well as the “brain-gut” axis
Deep-fried Atractylodes lancea rhizome alleviates spleen deficiency diarrhea–induced short-chain fatty acid metabolic disorder in mice by remodeling the intestinal flora
| Obras citantes distintas | 6 |
|---|---|
| Citas por año | 6 |
| Intervalo de citas | 2025 - 2027 (3) |
| Velocidad de citación | recent |
| Altamente citado | No |
| Tipos de cita | Neutras: 5 |