Factors influencing identification capability of adverse drug reactions in children aged 8–18 years based on social cognitive theory

Datos Bibliográficos

ID21284079
AutoresJing Zhang (0000-0002-6431-9286), Zhang J (Shandong Provincial Hospital), Xiaolin Xu (0000-0002-0689-4813, Capital Medical University), Xiao-Lin Xu, Ren-Chao Dong (Shandong Provincial Hospital), Yu Wang (0009-0005-4222-2626, Shandong Provincial Hospital), Zhong-Lan Wang (Shandong Provincial Hospital), Yi-chi Zhang (Shandong Provincial Hospital), Zhe Wang (0000-0002-3939-4452, Shandong Provincial Hospital), Xia Li (0000-0003-3050-8529, Guangdong Province Environmental Monitoring Center, autor de correspondencia), Li-Na Hao (Shandong Provincial Hospital, autor de correspondencia)
Año2026
Volumen266
Páginas106993
Fecha de publicación2026-06-01
Peer ReviewedSí
Open AccessSí
TipoARTICLE
RevistaActa Psychologica (JOURNAL)
Identificadores de la revistaISSN: 0001-6918 • E-ISSN: 1873-6297
EditorialElsevier BV (PUBLISHER)
DOI10.1016/j.actpsy.2026.106993
PMID42085972
OpenAlexW7160264827
IdiomaEN
Referencias citadas35

OBJECTIVE: To investigate the factors associated with Identification Capability of Adverse Drug Reactions in children aged 8-18 years. METHODS: A self-designed questionnaire based on Social Cognitive Theory was administered to children aged 8-18 years in China. The survey was conducted both online and offline. Structural equation modeling was applied to analyze the factors influencing the identification of Adverse Drug Reactions (ADRs) in children. RESULTS: A total of 5191 questionnaires were administered in this study, of which 4431 valid responses were included in the final analysis. All Pearson correlations among variables were statistically significant. All variables demonstrated high internal consistency (Cronbach's α > 0.7), and the data were suitable for factor analysis (KMO = 0.952 Bartlett's test, p 0.9). As indicated by the structural equation model, children's ability to identify adverse drug reactions was positively influenced by self-efficacy (β = 0.199, p < 0.05), media use (β = 0.163, p < 0.05), psychological well-being (β = 0.151, p < 0.05), medication literacy (β = 0.142, p < 0.05) and family environment (β = 0.141, p < 0.05). Additionally, the family environment exerted a significant positive effect on psychological well-being, which in turn significantly enhanced self-efficacy. CONCLUSION: Positive mental state, high medication literacy, and favorable growth environment are all contribute to an enhanced ability to self-identify adverse drug reactions. Targeted interventions are essential for promoting lifelong health management and ensuring medication safety in children

Adverse effect · Cognition · Confirmatory factor analysis · Drug · Identification (biology) · Psychological intervention · Social support · Structural equation modeling · Child and Animal Learning Development · Pharmaceutical studies and practices · Pharmacovigilance and Adverse Drug Reactions