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Naloxone Availability, Testing Drugs for Potency, and Solitary Use

Unpacking the Determinants of Overdose Prevention Behaviors

Datos Bibliográficos

ID21645819
AutoresCarl A Latkin (Department of Health, Behavior and Society, Johns Hopkins Bloomberg School of Public Health), Carl Latkin (0000-0002-7931-2116, Johns Hopkins University, autor de correspondencia), Lauren Dayton (0000-0002-1400-3670, Department of Health, Behavior and Society, Johns Hopkins Bloomberg School of Public Health), Haley Bonneau (Department of Health, Behavior and Society, Johns Hopkins Bloomberg School of Public Health), Melissa Davey-Rothwell (0000-0002-8483-9297, Johns Hopkins University), Melissa A Davey-Rothwell (Department of Health, Behavior and Society, Johns Hopkins Bloomberg School of Public Health), Leane Santos-Silva (Johns Hopkins University), Grace Yi (0000-0001-9560-3805, Department of Health, Behavior and Society, Johns Hopkins Bloomberg School of Public Health), Oluwaseun Falade‐Nwulia (0000-0003-2321-2295, Division of Infectious Diseases, Johns Hopkins School of Medicine), Oluwaseun Falade-Nwulia (Division of Infectious Diseases, Johns Hopkins School of Medicine)
Año2026
Volumen61
Número8
Páginas1185-1191
Fecha de publicación2026-07-03
Peer ReviewedSí
Open AccessSí
TipoARTICLE
RevistaSubstance Use & Misuse (JOURNAL)
Identificadores de la revistaISSN: 1082-6084 • E-ISSN: 1532-2491
EditorialInforma UK Limited (PUBLISHER • GB)
DOI10.1080/10826084.2025.2600637
PMID41404930
OpenAlexW4417429143
IdiomaEN
Referencias citadas26

BACKGROUND: Fatal and nonfatal opioid overdoses remain a pressing public health challenge. However, engagement in drug overdose prevention and response behaviors may vary across demographic and social contexts. OBJECTIVES: = 783). Ordered logistic regression models assessed factors associated with three key behaviors: testing-dosing to assess drug potency, naloxone availability while using with others, and solitary drug use. RESULTS: The three key overdose prevention behaviors were not strongly correlated with one another. Racial disparities emerged, with Black participants more likely to engage in test-dosing compared to White participants. Gender differences were also notable, with women less likely to use with others who have naloxone available when using drugs. Social network factors played a key role; having a "running buddy" was strongly protective against solitary drug use. CONCLUSIONS: These findings underscore the importance of tailored harm reduction interventions that address racial and gender disparities, enhance social networks, manage withdrawal, and enhance naloxone availability. Integrating harm reduction skill training into peer-driven naloxone distribution and overdose prevention programs, training non-drug-using network members, and addressing structural barriers may enhance overdose prevention strategies

Drug overdose · Harm · Harm reduction · Opioid overdose · Poison control · Psychological intervention · Unpacking · HIV, Drug Use, Sexual Risk · Opioid Use Disorder Treatment · Substance Abuse Treatment and Outcomes

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