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A 12-month projection to September 2022 of the Covid-19 epidemic in the UK using a dynamic causal model

Datos Bibliográficos

ID22085529
AutoresCameron Bowie (0000-0002-6956-3691, Axminster Hospital, autor de correspondencia), Cam Bowie, Karl J Friston (0000-0001-7984-8909, Wellcome Centre for Human Neuroimaging), Karl Friston
Año2022
Volumen10
Páginas999210-999210
Fecha de publicación2022-11-15
Peer ReviewedSí
Open AccessSí
TipoARTICLE
RevistaFrontiers in Public Health (JOURNAL)
Identificadores de la revistaISSN: 2296-2565 • E-ISSN: 2296-2565
EditorialFrontiers Media SA (PUBLISHER • CH)
DOI10.3389/fpubh.2022.999210
PMID36457320
OpenAlexW4309113879
IdiomaEN
Citas recibidas3
Referencias citadas18

Objectives: Predicting the future UK COVID-19 epidemic allows other countries to compare their epidemic with one unfolding without public health measures except a vaccine program. Methods: A Dynamic Causal Model was used to estimate key model parameters of the UK epidemic, such as vaccine effectiveness and increased transmissibility of Alpha and Delta variants, the effectiveness of the vaccine program roll-out and changes in contact rates. The model predicts the future trends in infections, long-COVID, hospital admissions and deaths. Results: Two-dose vaccination given to 66% of the UK population prevents transmission following infection by 44%, serious illness by 86% and death by 93%. Despite this, with no other public health measures used, cases will increase from 37 million to 61 million, hospital admissions from 536,000 to 684,000 and deaths from 136,000 to 142,000 over 12 months. A retrospective analysis (conducted after the original submission of this report) allowed a comparison of these predictions of morbidity and mortality with actual outcomes. Conclusion: Vaccination alone will not control the epidemic. Relaxation of mitigating public health measures carries several risks, which include overwhelming the health services, the creation of vaccine resistant variants and the economic cost of huge numbers of acute and chronic cases

Disease · Environmental health · Epidemic control · Epidemic model · Population · Public health · Vaccination · COVID-19 epidemiological studies · Demography · Medicine · SARS-CoV-2 and COVID-19 Research · Vaccine Coverage and Hesitancy · Pediatrics · Virology

  • Dynamic causal models in infectious disease epidemiology—an assessment of their predictive validity based on the Covid-19 epidemic in the UK 2020 to 2024

    Open Access•Cameron Bowie, Cam Bowie et al.•Frontiers in Public Health•2025

  • A follow up report validating long term predictions of the Covid-19 epidemic in the UK using a dynamic causal model

    Open Access•Cameron Bowie, Cam Bowie et al.•Frontiers in Public Health•2024

  • Using a Dynamic Causal Model to validate previous predictions and offer a 12-month forecast of the long-term effects of the Covid-19 epidemic in the UK

    Open Access•Cameron Bowie, Cam Bowie et al.•Frontiers in Public Health•2023

  • Effectiveness of Covid-19 Vaccines against the B.1.617.2 (Delta) Variant

    Jamie Lopez Bernal, Nick Andrews et al.•New England Journal of Medicine•2021

  • Bayesian model averaging

    Jennifer A Hoeting, David Madigan et al.•Statistical Science•1999

  • Modeling Early Phases of Covid-19 Pandemic in Northern Italy and Its Implication for Outbreak Diffusion

    Open Access•Daniela Gandolfi, Giuseppe Pagnoni et al.•Frontiers in Public Health•2021

Obras citantes distintas3
Citas por año1
Intervalo de citas2023 - 2025 (3)
Velocidad de citaciónrecent
Altamente citadoNo
Tipos de citaNeutras: 3
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