Association Between Obesity and Psychiatric Disorders in the US Adult Population

Datos Bibliográficos

ID23359470
AutoresGREGORY E SIMON (0000-0003-2859-5467, Group Health Cooperative), MICHAEL VON KORFF (Group Health Cooperative), Kathleen Saunders (Group Health Cooperative), Diana L Miglioretti (0000-0002-5547-1833, Group Health Cooperative), Paul K Crane (0000-0003-4278-7465, University of Washington), Gerald van Belle (0000-0002-8552-158X, University of Washington), R C Kessler (0000-0003-4831-2305, Harvard University Press)
Año2006
Volumen63
Número7
Páginas824
Fecha de publicación2006-07-01
Peer ReviewedSí
Open AccessNo
TipoARTICLE
RevistaArchives of General Psychiatry (JOURNAL)
Identificadores de la revistaISSN: 0003-990X • E-ISSN: 1538-3636
EditorialAmerican Medical Association (AMA) (PUBLISHER)
DOI10.1001/archpsyc.63.7.824
PMID16818872
PMCIDPMC1913935
OpenAlexW2153393568
IdiomaEN
Citas recibidas92
Referencias citadas27

BACKGROUND: Epidemiologic data suggest an association between obesity and depression, but findings vary across studies and suggest a stronger relationship in women than men. OBJECTIVE: To evaluate the relationship between obesity and a range of mood, anxiety, and substance use disorders in the US general population. DESIGN: Cross-sectional epidemiologic survey. SETTING: Nationally representative sample of US adults. PARTICIPANTS: A total of 9125 respondents who provided complete data on psychiatric disorder, height, and weight. Response rate was 70.9%. MAIN OUTCOME MEASURES: Participants completed an in-person interview, including assessment of a range of mental disorders (assessed using the World Health Organization Composite International Diagnostic Interview) and height and weight (by self-report). RESULTS: Obesity (defined as body mass index [calculated as weight in kilograms divided by the square of height in meters] of > or =30) was associated with significant increases in lifetime diagnosis of major depression (odds ratio [OR], 1.21; 95% confidence interval [CI], 1.09-1.35), bipolar disorder (OR, 1.47; 95% CI, 1.12-1.93), and panic disorder or agoraphobia (OR, 1.27; 95% CI, 1.01-1.60). Obesity was associated with significantly lower lifetime risk of substance use disorder (OR, 0.78; 95% CI, 0.65-0.93). Subgroup analyses found no difference in these associations between men and women, but the association between obesity and mood disorder was strongest in non-Hispanic whites (OR, 1.38; 95% CI, 1.20-1.59) and college graduates (OR, 1.44; 95% CI, 1.14-1.81). CONCLUSIONS: Obesity is associated with an approximately 25% increase in odds of mood and anxiety disorders and an approximately 25% decrease in odds of substance use disorders. Variation across demographic groups suggests that social or cultural factors may moderate or mediate the association between obesity and mood disorder.

Agoraphobia · Anxiety · Body mass index · Confidence interval · Depression (economics) · Environmental health · Major depressive disorder · Mood · Mood disorders · Obesity · Odds ratio · Panic disorder · Population · Psychiatry · Bariatric Surgery and Outcomes · Demography · Eating Disorders and Behaviors · Internal Medicine · Medicine · Obesity and Health Practices · Psychology