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The Origin and Spread of Leprosy

Historical, Skeletal, and Molecular Data

Datos Bibliográficos

ID3384470
AutoresSamuel Mark (0000-0002-9173-5779, Texas A&M University at Galveston, autor de correspondencia)
Año2018
Volumen49
Número3
Páginas367-395
Fecha de publicación2018-11-01
Peer ReviewedSí
Open AccessNo
TipoARTICLE
RevistaThe Journal of Interdisciplinary History (JOURNAL)
Identificadores de la revistaISSN: 0022-1953 • E-ISSN: 1530-9169
EditorialMIT Press - Journals (PUBLISHER)
DOI10.1162/jinh_a_01301
OpenAlexW2901704624
IdiomaEN
Referencias citadas30

East Africa and India have recently been proposed as places of origin for leprosy, based primarily on the geographical mapping of sixteen single-nucleotide polymorphism subtypes (snps). When comparing these data with historical texts, however, obstacles become apparent for both interpretations. Large population movements, a lack of divergence date ranges for some snp subtypes, and the discovery of a second strain of leprosy further complicate the geography of the disease. Dated skeletons with snp subtypes and molecular data, along with the informed collaboration of historical evidence, are key to determining the place of origin for both leprosy species

Biology · Divergence (linguistics) · Evolutionary biology · Gene · Genealogy · Genotype · Geography · Leprosy · Linguistics · Population · Single-nucleotide polymorphism · SNP · Sociology · Demography · Genetics · History · Immunology · Infectious Diseases and Tuberculosis · Leprosy Research and Treatment · Tuberculosis Research and Epidemiology

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