Long-lasting analgesic effect of the psychedelic drug changa

A case report

Datos Bibliográficos

ID4686302
AutoresGenís Ona (0000-0003-2741-2876, Universitat Rovira i Virgili, autor de correspondencia), Sebastián Peña Troncoso (0000-0002-5438-0868, Universitat Rovira i Virgili), Sebastián Troncoso
Año2019
Volumen3
Número1
Páginas7-13
Fecha de publicación2019-03-01
Peer ReviewedSí
Open AccessSí
TipoARTICLE
RevistaJournal of Psychedelic Studies (JOURNAL)
Identificadores de la revistaISSN: 2559-9283 • E-ISSN: 2559-9283
EditorialAkademiai Kiado Zrt (PUBLISHER)
DOI10.1556/2054.2019.001
OpenAlexW2914689341
IdiomaEN
Citas recibidas1
Referencias citadas66

Background and aims: Pain is the most prevalent symptom of a health condition, and it is inappropriately treated in many cases. Here, we present a case report in which we observe a long-lasting analgesic effect produced by changa, a psychedelic drug that contains the psychoactive N,N-dimethyltryptamine and ground seeds of Peganum harmala, which are rich in -carbolines. Methods: We describe the case and offer a brief review of supportive findings. Results: A long-lasting analgesic effect after the use of changa was reported. Possible analgesic mechanisms are discussed. We suggest that both pharmacological and non-pharmacological factors could be involved. Conclusion: These findings offer preliminary evidence of the analgesic effect of changa, but due to its complex pharmacological actions, involving many neurotransmitter systems, further research is needed in order to establish the specific mechanisms at work

Analgesic · Dopamine · Drug · Neurotransmitter systems · Cannabis and Cannabinoid Research · Chemical synthesis and alkaloids · Medicine · Psychedelics and Drug Studies · Internal Medicine · Pharmacology