The "AMA-Brazil" cooperative project

A nation-wide assessment of the clinical and epidemiological profile of Aids-related deaths in Brazil in the antiretroviral treatment era

Datos Bibliográficos

ID5226071
AutoresMaria Amelia Veras (0000-0002-1159-5762, Santa Casa de São Paulo, Brasil), Maria Amelia De Sousa Mascena Veras (Santa Casa de São Paulo, Brasil), Manoel C A Ribeiro (0000-0003-2124-1463, Santa Casa de São Paulo, Brasil), Leda Fátima Jamal (Secretaria de Estado da Saúde de São Paulo, Brasil), Willi Mcfarland (0000-0002-4148-5660, University of California, USA), Francisco I Bastos (0000-0001-5970-8896, Fundação Oswaldo Cruz), Kiune Bezerra Ribeiro (0000-0002-8095-5979, Santa Casa de São Paulo, Brasil), Karina Braga Ribeiro (Santa Casa de São Paulo, Brasil), Rita Barradas Barata (0000-0002-7215-9788, Santa Casa de São Paulo, Brasil), José Cássio De Moraes (0000-0003-4512-662X, Santa Casa de São Paulo, Brasil), Arthur Reingold (University of California, Berkeley), Arthur L Reingold (University of California, USA)
Año2011
Volumen27
Númerosuppl 1
Páginass104-s113
Fecha de publicación2011-01-01
Peer ReviewedSí
Open AccessSí
TipoARTICLE
RevistaCadernos de Saude Publica (JOURNAL)
Identificadores de la revistaISSN: 0102-311X • E-ISSN: 1678-4464
EditorialFapUNIFESP (SciELO) (PUBLISHER)
DOI10.1590/s0102-311x2011001300011
PMID21503518
OpenAlexW2153867007
SCIELO_PIDS0102-311X2011001300011
IdiomaEN
Citas recibidas4
Referencias citadas9

The objective of this study was to assess the profile of AIDS-related deaths in the post antiretroviral therapy (ART) scale up period in Brazil. A case-control study was conducted including a nationally probabilistic sample of AIDS deaths and living controls. Data were abstracted from medical records and nation-wide databases of AIDS cases, mortality, ART care, and laboratory testing. Interrupted (adjusted odds ratio - AOR 4.35, 95%CI: 3.15-6.00) or no use of ART (AOR 2.39, 95%CI: 1.57-3.65) was the strongest predictor of death, followed by late diagnosis (AOR 3.95, 95%CI: 2.68-5.82). Criterion other than CD4 < 350 had a higher likelihood of death (AOR 1.65, 95%CI: 1.14-2.40). Not receiving recommended vaccines (AOR, 1.76, 95%CI: 1.21-2.56), presenting AIDS-related diseases (AOR 2.19, 95%CI: 1.22-3.93) and tuberculosis (AOR 1.50, 95%CI: 1.14-1.97) had higher odds of death. Being an injecting drug user (IDU) had a borderline association with higher odds of death, while homo/bisexual exposure showed a protective effect. Despite remarkable successes, Brazilians continue to die of AIDS in the post-ART scale up period. Many factors contributing to continued mortality are preventable

Logistic regression · Odds · Odds ratio · Tuberculosis · Demography · Epidemiology · HIV Research and Treatment · HIV, Drug Use, Sexual Risk · HIV/AIDS Research and Interventions · Internal Medicine · Medicine