JC virus genotype profile in the Mamanwa, a Philippine Negrito tribe, and implications for its population history

Datos Bibliográficos

ID6135562
AutoresJasmin Jiji Miranda (National Institute of Molecular Biology and Biotechnology, University of the Philippines), Tomokazu Takasaka (The University of Tokyo), Huai-Ying Zheng (The University of Tokyo), Tadaichi Kitamura (0000-0002-3009-2546, The University of Tokyo), Yoshiaki Yogo (The University of Tokyo)
Año2004
Volumen112
Número2
Páginas173-178
Fecha de publicación2004-01-01
Peer ReviewedSí
Open AccessSí
TipoARTICLE
RevistaAnthropological Science (JOURNAL)
Identificadores de la revistaISSN: 0918-7960 • E-ISSN: 1348-8570
EditorialAnthropological Society of Nippon (PUBLISHER • JP)
DOI10.1537/ase.03115
OpenAlexW2046983854
IdiomaEN
Citas recibidas5
Referencias citadas33

JC virus (JCV) is ubiquitous in the human population, usually being transmitted from parents to children during cohabitation. JCV genotyping is a useful means of elucidating the origins of various ethnic groups in the world. We used this method to gain insights into the origin of the Mamanwa, a Philippine Negrito tribe in Northeast Mindanao. We found that the Mamanwa carried two major JCV genotypes, B3-b/2E and SC-f/7A. This was in contrast with the JCV genotype profile of modern Filipinos who carry up to five genotypes, with B3-b/2E showing only a low frequency. B3-b/2E is spread throughout Oceania but rare on the Asian continent. In contrast, SC-f/7A is spread throughout Southeast Asia (including neighboring Oceanic islands) but rare in Remote Oceania. The present findings thus suggest that the Mamanwa tribe was formed by early colonization by people carrying B3-b/2E followed by an admixture of more recent immigrants carrying SC-f/7A. As the indigenous tribe (the Chamorro) in the Mariana Islands has essentially the same JCV genotype profile as the Mamanwa, other indigenous tribes in Southeast Asian and Oceanic islands may have a population history analogous to that suggested for the Mamanwa

Biology · Ethnic group · Ethnology · Gene · Genotype · Genotyping · Geography · Indigenous · JC virus · Population · Sociology · Tribe · Virus · Anthropology · Demography · History · Plant Virus Research Studies · Polyomavirus and related diseases · Viral Infections and Outbreaks Research · Ecology · Genetics · Virology