Peopling of Japan as Revealed by Genotyping of Urinary JC Virus DNA
Datos Bibliográficos
It has been shown that the typing of urinary JC polyomavirus (JCV) DNA offers a novel means of tracing human migrations. We used this approach to elucidate the colonization of the Japanese Archipelago. Approximately 1, 000 JCV DNA-positive urine samples were collected throughout the Japanese Archipelago, and used to amplify a 610-base-pair JCV DNA region (IG region). We determined about 100 IG sequences, from which a phylogenetic tree was constructed to classify them into distinct genotypes. The rest of the amplified fragments were classified into genotypes on the basis of the results of a restriction fragment length polymorphism analysis. Two major (CY and MY) and three minor JCV genotypes (SC, B1-a, and EU) were identified. There was marked variation in the frequency of these JCV genotypes among the sites of sample collection. For example, MY was more frequently detected in northeastern areas and CY was predominant in southwestern areas. The possibility that the detection of EU in Japan is a result of recent Caucasian immigration was excluded by a phylogenetic comparison of Japanese and European EU isolates. These findings suggest that not only two major groups carrying CY or MY but also three minor groups carrying SC, B1-a or EU migrated to the Japanese Archipelago and that all contributed to founding modern Japan
Archipelago · Biology · Gene · Genotype · Genotyping · JC virus · Phylogenetic tree · Progressive multifocal leukoencephalopathy · Restriction fragment length polymorphism · Typing · Virus · Parvovirus B19 Infection Studies · Plant Virus Research Studies · Polyomavirus and related diseases · Genetics · Virology
Dispersal of southeastern Asians based on a global phylogenetic analysis of JC polyomavirus isolates of genotype SC
Strains of JC virus in Amerind‐speakers of North America (Salish) and South America (Guaraní), Na‐Dene‐speakers of New Mexico (Navajo), and modern Japanese suggest links through an ancestral Asian population
Genetic diversity of JC virus in the Saami and the Finns
JC Virus Genotypes in the Western Pacific Suggest Asian Mainland Relationships and Virus Association with Early Population Movements
Two distinct genotypes (MY-x and MX) of JC virus previously identified in Hokkaido Ainu
JC Virus Genotypes in Northwestern China
Phylogenetic Analysis of JC Virus DNAs Detected in Ainus
Confidence Limits on Phylogenies
Confidence Limits on Phylogenies
Mitochondrial DNA and human evolution
Clustal W
A simple method for estimating evolutionary rates of base substitutions through comparative studies of nucleotide sequences
Population history of Japan as viewed from cranial nonmetric variation
Genetic origins of the Japanese
Genetic origins of the Japanese
| Obras citantes distintas | 7 |
|---|---|
| Citas por año | 0,28 |
| Intervalo de citas | 2001 - 2006 (6) |
| Velocidad de citación | historical |
| Altamente citado | No |
| Tipos de cita | Neutras: 7 |