Cross-Cultural Considerations in the Recruitment of Latinos of Mexican Origin into HIV/Aids Clinical Trials in the U.S.-Mexico Border Region

Despite increasing prevalence of HIV among U.S. Latinos, participation in HIV clinical trials is low. Barriers to HIV clinical trial participation in U.S. Latinos are not well understood. Using in-depth, semistructured interviews with HIV care providers serving HIV-positive Latinos and focus groups with HIV-positive Mexican-origin Latinos, we assessed cross-cultural barriers (e.g., stigma and linguistic) to HIV clinical trials in San Diego, California, bordering Mexico. Cross-cultural barriers were explored using grounded theory analytical techniques. Patient-provider concordance on the nature of HIV-related stigma, linguistic barriers, the impact of U.S.-Mexico border on Latino patients and participation in clinical trials were found. Providers described care access challenges faced by patients of Mexican-origin, particularly in light of immigration and U.S. border policy. HIV-related stigma and communication barriers among Latinos remain important obstacles to clinical trials participation and care access in the United States

Clinical trial · Concordance · Family medicine · Focus group · Human immunodeficiency virus (HIV · Immigration · Political science · Psychiatry · Social stigma · Sociology · Stigma (botany · HIV, Drug Use, Sexual Risk · HIV/AIDS Research and Interventions · Medicine · Migration, Health and Trauma · Gerontology

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