Mitochondrial DNA structure in North Africa reveals a genetic discontinuity in the Nile Valley
Datos Bibliográficos
| ID | 8314599 |
|---|---|
| Autores | Karima Fadhlaoui‐zid (0000-0002-8980-9716, Tunis University), Laura Rodríguez‐Botigué, Laura R Botigué (0000-0001-7114-5168, Universitat Pompeu Fabra), Nejib Naoui, Amel Benammar-Elgaaied (0000-0002-3008-0297, Tunis University), Amel Benammar‐Elgaaied, Francesc Calafell (0000-0002-1083-9438, Universitat Pompeu Fabra), Domingo Comas (0000-0002-5075-0956, Universitat Pompeu Fabra, autor de correspondencia), David Comas |
| Año | 2011 |
| Volumen | 145 |
| Número | 1 |
| Páginas | 107-117 |
| Fecha de publicación | 2011-05-01 |
| Peer Reviewed | Sí |
| Open Access | Sí |
| Tipo | ARTICLE |
| Revista | American Journal of Physical Anthropology (JOURNAL) |
| Identificadores de la revista | ISSN: 0002-9483 • E-ISSN: 1096-8644 |
| Editorial | Wiley (PUBLISHER • GB) |
| DOI | 10.1002/ajpa.21472 |
| PMID | 21312180 |
| OpenAlex | W2149688157 |
| Idioma | EN |
| Citas recibidas | 11 |
| Referencias citadas | 72 |
Human population movements in North Africa have been mostly restricted to an east‐west direction due to the geographical barriers imposed by the Sahara Desert and the Mediterranean Sea. Although these barriers have not completely impeded human migrations, genetic studies have shown that an east‐west genetic gradient exists. However, the lack of genetic information of certain geographical areas and the focus of some studies in parts of the North African landscape have limited the global view of the genetic pool of North African populations. To provide a global view of the North African genetic landscape and population structure, we have analyzed ∼2,300 North African mitochondrial DNA lineages (including 269 new sequences from Libya, in the first mtDNA study of the general Libyan population). Our results show a clinal distribution of certain haplogroups, some of them more frequent in Western (H, HV0, L1b, L3b, U6) or Eastern populations (L0a, R0a, N1b, I, J) that might be the result of human migrations from the Middle East, sub‐Saharan Africa, and Europe. Despite this clinal pattern, a genetic discontinuity is found in the Libyan/Egyptian border, suggesting a differential gene flow in the Nile River Valley. Finally, frequency of the post‐LGM subclades H1 and H3 is predominant in Libya within the H sequences, highlighting the magnitude of the LGM expansion in North Africa. Am J Phys Anthropol, 2011. © 2011 Wiley‐Liss, Inc
Allele · Biology · Gene · Gene flow · Gene pool · Genetic diversity · Genetic structure · Genetic variation · Geography · Haplogroup · Haplotype · Human migration · Mitochondrial DNA · Population · Demography · Ecology · Forensic and Genetic Research · Forensic Anthropology and Bioarchaeology Studies · Genetic diversity and population structure · Genetics
Ethnic composition and genetic differentiation of the Libyan population
Linking between genetic structure and geographical distance
Allele frequencies for 15 autosomal STR markers in the Libyan population
Mitochondrial DNA structure of an isolated Tunisian Berber population and its relationship with Mediterranean populations
The genetic landscape of Mediterranean North African populations through complete mtDNA sequences
Distinctive genetic signatures of Alu/STR compound systems revealed by analyses of Mediterranean and Middle East populations
Ancient and recent Middle Eastern maternal genetic contribution to North Africa as viewed by mtDNA diversity in Tunisian Arab populations
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Reanalysis and revision of the Cambridge reference sequence for human mitochondrial DNA
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Origin, Diffusion, and Differentiation of Y-Chromosome Haplogroups E and J
Atlas of world population history
Islands Inside an Island
Human mitochondrial DNA sequence variation in the Moroccan population of the Souss area
Post‐last glacial maximum expansion from Iberia to North Africa revealed by fine characterization of mtDNA H haplogroup in Tunisia
Genetic variation in North Africa and Eurasia
Female Gene Pools of Berber and Arab Neighboring Communities in Central Tunisia
Substructure of a Tunisian Berber Population as Inferred from 15 Autosomal Short Tandem Repeat Loci
Late Quaternary human settlement patterning in the Jebel Gharbi
Atlas of World Population History
| Obras citantes distintas | 11 |
|---|---|
| Citas por año | 0,73 |
| Intervalo de citas | 2011 - 2018 (8) |
| Velocidad de citación | historical |
| Altamente citado | No |
| Tipos de cita | Neutras: 11 |