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Interethnic variability in birth weight and genetic background

A study of placental alkaline phosphatase

Datos Bibliográficos

ID8317199
AutoresA Amante (University of Rome Tor Vergata), Paola Borgiani (0000-0003-0859-4328, University of Rome Tor Vergata), A Gimelfarb (University of Chicago), F Gloria-Bottini, F Gloria‐bottini (University of Rome Tor Vergata, autor de correspondencia)
Año1996
Volumen101
Número4
Páginas449-453
Fecha de publicación1996-12-01
Open AccessSí
TipoARTICLE
RevistaAmerican Journal of Physical Anthropology (JOURNAL)
Identificadores de la revistaISSN: 0002-9483 • E-ISSN: 1096-8644
EditorialWiley (PUBLISHER • GB)
DOI10.1002/(sici)1096-8644(199612)101:4<449::aid-ajpa1>3.0.co;2-r
PMID9016360
OpenAlexW2088028828
IdiomaEN
Citas recibidas2
Referencias citadas14

The relationship between human placental alkaline phosphatase (PLAP) genotype and birth weight is investigated in a sample of white, black and Puerto-Rican new-born infants from New Haven, Connecticut (total 710 subjects). Black and Puerto-Rican infants show a higher incidence of growth retardation and a higher frequency of ALPp*1/*1 genotype as compared to whites. The proportion of newborns with a low birth weight (below the 10th percentile) is lower in infants with ALPp*1/*1 genotype than in those with other PLAP genotypes, especially among non-whites. It is argued that the higher frequency of ALPp*1 allele among non-whites might be, at least in part, a consequence of their adaptation in the past to environmental conditions adverse to optimal intrauterine development.

Alkaline phosphatase · Biology · Enzyme · Obstetrics · Placental alkaline phosphatase · Alkaline Phosphatase Research Studies · Biochemistry · Birth, Development, and Health · Genetics · Medicine · Selenium in Biological Systems

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Citas por año0,09
Intervalo de citas2003 - 2025 (23)
Altamente citadoNo

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