DYS19 and DYS199 loci in a Chilean population of mixed ancestry

Datos Bibliográficos

ID8318993
AutoresL Cifuentes (0000-0001-7552-0279, University of Chile, autor de correspondencia), Rodrigo Morales (0000-0002-9237-8670, Ministry of Health), D Sepúlveda, H Jorquera (Ministry of Health), M Acuña (0000-0002-4100-1873, University of Chile)
Año2004
Volumen125
Número1
Páginas85-89
Fecha de publicación2004-09-01
Peer ReviewedSí
Open AccessSí
TipoARTICLE
RevistaAmerican Journal of Physical Anthropology (JOURNAL)
Identificadores de la revistaISSN: 0002-9483 • E-ISSN: 1096-8644
EditorialWiley (PUBLISHER • GB)
DOI10.1002/ajpa.10380
PMID15293334
OpenAlexW2121407098
IdiomaEN
Citas recibidas5
Referencias citadas21

The current Chilean population originated from admixture between aboriginal populations (Amerindians) and Spanish conquerors of European origin. Consequently, the unions that gave rise to the Chilean population were chiefly between Spanish males and aboriginal females, and not the converse. To test the hypothesis that the Y chromosome of the Chilean population is mainly of Spanish origin, while the other chromosomes are from mixed (European and aboriginal) origin, we studied the DYS19 and DYS199 loci in two samples. One sample was obtained from a high socioeconomic stratum, while a second sample was from a low stratum. We studied male blood donors (N = 187) from Santiago, the capital of the country. Subjects were typed for the autosomal ABO and Rh (locus D) blood groups, and for the Y‐linked DYS19 and the DYS199 loci, reported as Y‐chromosome haplotypes. The aboriginal admixture was estimated for each genetic marker. The percentage of aboriginal admixture was 38.17% for the ABO system and 31.28% for the Rh system in the low socioeconomic stratum and 19.22% and 22.5%, respectively, in the high stratum. Y‐chromosome haplotype frequencies constructed from the DYS19 and DYS199 loci demonstrated that the main haplotypes were DYS19*14/DYS199 C, as is often the case with many European populations, and DYS19*13/DYS199 C. The aboriginal admixture from Y‐haplotype frequencies was estimated to be 15.83% in the low socioeconomic stratum and 6.91% in the high stratum. These values are lower than the values found using autosomal genetic markers, and are consistent with the historical background of the population studied. This study highlights the population genetic consequences of the asymmetric pattern of genome admixture between two ancestral populations (European and Amerindian). Am J Phys Anthropol, 2004. © 2004 Wiley‐Liss, Inc

ABO blood group system · Allele · Biology · Gene · Genotype · Haplotype · Locus (genetics) · Microsatellite · Population · Socioeconomic status · Sociology · Y chromosome · Demography · Forensic and Genetic Research · Genetic Associations and Epidemiology · Genetics · Race, Genetics, and Society