E-Prescribing and Adverse Drug Events

An Observational Study of the Medicare Part D Population With Diabetes

Datos Bibliográficos

ID9101792
AutoresMeghan Hufstader Gabriel (0000-0003-3331-2169, University of Central Florida, autor de correspondencia), Christopher Powers (0000-0002-5131-9711, Centers for Medicare and Medicaid Services, Office of Enterprise Data and Analytics, Baltimore, MD), Christopher A Powers (Centers for Medicare and Medicaid Services), William Encinosa (0000-0002-1970-5620, Agency for Healthcare Research and Quality), Jefferson Bynum (0000-0003-1481-4462, Dartmouth Institute for Health Policy and Clinical Practice), Julie P W Bynum (The Dartmouth Institute for Health Policy and Clinical Practice, Geisel School of Medicine at Dartmouth, Lebanon, NH)
Año2017
Volumen55
Número5
Páginas456-462
Fecha de publicación2017-05-01
Peer ReviewedSí
Open AccessNo
TipoARTICLE
RevistaMedical Care (JOURNAL)
Identificadores de la revistaISSN: 0025-7079 • E-ISSN: 1537-1948
EditorialOvid Technologies (Wolters Kluwer Health) (PUBLISHER)
DOI10.1097/mlr.0000000000000684
PMID28060051
OpenAlexW2570760438
IdiomaEN
Citas recibidas1
Referencias citadas19

BACKGROUND: Although the adoption of e-prescriptions among physicians has increased substantially under the Medicare Improvements for Patients and Providers Act and Meaningful Use programs, little is known of its impact on patient outcomes. OBJECTIVE: To examine the impact of e-prescribing on emergency visits or hospitalizations for diabetes-related adverse drug events (ADEs) including hypoglycemia. DESIGN: This is a prospective, observational cohort study with patient fixed effects. SETTING: 2011-2013 fee for service Medicare. PATIENTS: In total, 3.1 million Medicare fee for service, Part D enrolled beneficiaries over age 66 with diabetes mellitus and at least 90 days of antidiabetic medications. MEASUREMENTS: E-prescribing was measured as the percentage of all prescriptions a person received transmitted to the pharmacy electronically. The outcome measure was the occurrence of an emergency department (ED) visit or hospitalization for hypoglycemia or diabetes-related ADE. RESULTS: Unadjusted results show that there were 21 ADEs per 1000 beneficiaries that had ≥75% of their medications e-prescribed. Beneficiaries with lower e-prescribing levels had significantly higher numbers of ADEs. We found a robust association between the greater use of electronic prescriptions in the outpatient setting and the lower risk of an inpatient or ED visit for an ADE event among Medicare beneficiaries with diabetes in our adjusted analysis. At the e-prescribing threshold of 75% and above, significant reductions in ADE risk can be seen. LIMITATIONS: As an observational study, the results show an association but do not prove causation. CONCLUSIONS: Use of e-prescribing is associated with lower risk of an ED visit or hospitalization for diabetes-related ADE

Adverse effect · Drug · MEDLINE · Political science · Electronic Health Records Systems · Medication Adherence and Compliance · Medicine · Pharmaceutical Practices and Patient Outcomes · Pharmacology