Genetic studies of human apolipoproteins. XVII
Population genetics of apolipoprotein polymorphisms in American Samoa
Datos Bibliográficos
| ID | 9568258 |
|---|---|
| Autores | Douglas E Crews (0000-0002-3321-5898, Northwestern University, autor de correspondencia), M Ilyas Kamboh (0000-0002-3453-1438, University of Pittsburgh), James R Bindon (University of Alabama), Robert E Ferrell (University of Pittsburgh) |
| Año | 1991 |
| Volumen | 84 |
| Número | 2 |
| Páginas | 165-170 |
| Fecha de publicación | 1991-02-01 |
| Peer Reviewed | Sí |
| Open Access | Sí |
| Tipo | ARTICLE |
| Revista | American Journal of Physical Anthropology (JOURNAL) |
| Identificadores de la revista | ISSN: 0002-9483 • E-ISSN: 1096-8644 |
| Editorial | Wiley (PUBLISHER • GB) |
| DOI | 10.1002/ajpa.1330840206 |
| PMID | 2021192 |
| OpenAlex | W2033653713 |
| Idioma | EN |
| Citas recibidas | 8 |
| Referencias citadas | 16 |
Variation in human apolipoprotein genes is a major source of phenotypic differences in human lipid metabolism. Data regarding genetic variation at apolipoprotein loci in various populations are only beginning to accumulate, and they suggest that different populations vary widely in distribution of apolipoprotein alleles. Using isoelectric focusing‐immunoblotting techniques, we screened 67 serum samples from self‐identified Samoan residents of American Samoa to investigate structural variation at six apolipoprotein loci: A‐I, A‐II, A‐IV, C‐II, E, and H. The APO A‐I, A‐II, and C‐II loci were found to be monomorphic by isoelectrical focusing. In Samoans, the common three‐allele polymorphism was observed for APO E, with no striking differences in frequencies from Caucasian populations. The three common alleles of the APO H locus also were identified; however, frequencies of the less common alleles (APO H * I and APO H *3) were different from those observed elsewhere for Caucasians
Allele · Allele frequency · Apolipoprotein B · Apolipoprotein E · Biology · Cholesterol · Disease · Gene · Genetic variation · Locus (genetics · Population · Advanced Proteomics Techniques and Applications · Endocrinology · Genetic Associations and Epidemiology · Genetics · Internal Medicine · Medicine · Metabolomics and Mass Spectrometry Studies
Renin, ANP, ACE polymorphisms, blood pressure and age in American Samoans
Apolipoprotein polymorphisms and phenotypic variability in American Samoans
Health transition in the Pacific Islands
Ethnicity and human biology
Social status, social context, and arterial blood pressure
Using the Social-Ecological Model as a research and intervention framework to understand and mitigate obesogenic factors in Samoan populations
Apolipoprotein H Genetic Variability in the Population of Krk Island, Croatia
Population genetics of apolipoproteins A‐IV, E, and H, and the angiotensin converting enzyme (ACE)
| Obras citantes distintas | 8 |
|---|---|
| Citas por año | 0,24 |
| Intervalo de citas | 1993 - 2010 (18) |
| Velocidad de citación | historical |
| Altamente citado | No |
| Tipos de cita | Neutras: 8 |