Guanglu Che
Biographic Data
| ID | 10028696 |
|---|---|
| NAME | Guanglu Che |
| GIVEN NAMES | Guanglu |
| FAMILY NAME | Che |
| SIGNATURE | CHE G |
| AFFILIATIONS | Sichuan University |
| ORCID | 0000-0002-4051-583X |
| VERIFIED | Yes |
| TOTAL WORKS | 4 |
| TOTAL CITATIONS | 0 |
| WORKS AS AUTHOR | 4 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 2023 |
| LATEST PUBLICATION YEAR | 2026 |
| H-INDEX | 0 |
Clinical and epidemiological characteristics of cat scratch disease in children from southwestern China
Background and aim Cat scratch disease (CSD) is a zoonotic infection predominantly caused by Bartonella henselae , typically featured by regional lymphadenopathy and febrile illness. Although these classic features characterize most cases, the clinical spectrum extends to severe systemic manifestations including meningitis and neuroretinitis, leading to poor prognosis. Given this potential for diverse clinical presentations, prompt microbiologica…
Comparative evaluation of two DNA methylation assays for triage of hrHPV E6/E7 mRNA–positive women
Background The low specificity of high-risk human papillomavirus (hrHPV) testing necessitates effective triage strategies to avoid unnecessary colposcopy. DNA methylation testing shows promise, but its performance specifically in hrHPV E6/E7 mRNA-positive women, a population with active oncogenic activity, requires further evaluation. Methods This study evaluated the clinical performance of two commercial methylation-specific PCR assays, GynTect …
MNGS helped diagnose scrub typhus-associated HLH in children
Background Scrub typhus, caused by the Orientia tsutsugamushi (Ot) , is a widespread vector-borne disease transmitted by chigger mites. Hemophagocytic lymphohistiocytosis (HLH) is considered to be one of the potentially severe complications. The diagnosis of scrub typhus-associated HLH may be overlooked due to the non-specific clinical characteristics and the absence of pathognomonic eschar. Case presentation We obtained clinical data from two pa…
Leishmania donovani visceral leishmaniasis diagnosed by metagenomics next-generation sequencing in an infant with acute lymphoblastic leukemia
Background Visceral leishmaniasis (VL) is a neglected vector-borne tropical disease caused by Leishmania donovani ( L. donovani ) and Leishmania infantum ( L. infantum ). Due to the very small dimensions of the protozoa impounded within blood cells and reticuloendothelial structure, diagnosing VL remains challenging. Case presentation Herein, we reported a case of VL in a 17-month-old boy with acute lymphoblastic leukemia (ALL). The patient was a…
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Leishmania donovani visceral leishmaniasis diagnosed by metagenomics next-generation sequencing in an infant with acute lymphoblastic leukemia
Background Visceral leishmaniasis (VL) is a neglected vector-borne tropical disease caused by Leishmania donovani ( L. donovani ) and Leishmania infantum ( L. infantum ). Due to the very small dimensions of the protozoa impounded within blood cells and reticuloendothelial structure, diagnosing VL remains challenging. Case presentation Herein, we reported a case of VL in a 17-month-old boy with acute lymphoblastic leukemia (ALL). The patient was a…
MNGS helped diagnose scrub typhus-associated HLH in children
Background Scrub typhus, caused by the Orientia tsutsugamushi (Ot) , is a widespread vector-borne disease transmitted by chigger mites. Hemophagocytic lymphohistiocytosis (HLH) is considered to be one of the potentially severe complications. The diagnosis of scrub typhus-associated HLH may be overlooked due to the non-specific clinical characteristics and the absence of pathognomonic eschar. Case presentation We obtained clinical data from two pa…
Comparative evaluation of two DNA methylation assays for triage of hrHPV E6/E7 mRNA–positive women
Background The low specificity of high-risk human papillomavirus (hrHPV) testing necessitates effective triage strategies to avoid unnecessary colposcopy. DNA methylation testing shows promise, but its performance specifically in hrHPV E6/E7 mRNA-positive women, a population with active oncogenic activity, requires further evaluation. Methods This study evaluated the clinical performance of two commercial methylation-specific PCR assays, GynTect …
Clinical and epidemiological characteristics of cat scratch disease in children from southwestern China
Background and aim Cat scratch disease (CSD) is a zoonotic infection predominantly caused by Bartonella henselae , typically featured by regional lymphadenopathy and febrile illness. Although these classic features characterize most cases, the clinical spectrum extends to severe systemic manifestations including meningitis and neuroretinitis, leading to poor prognosis. Given this potential for diverse clinical presentations, prompt microbiologica…
Disease (3 works) · Immunology (2 works) · Internal Medicine (2 works) · Medicine (2 works) · MEDLINE (2 works) · Research on Leishmaniasis Studies (2 works) · Amphotericin B (1 work) · Antibiotics (1 work) · Autoimmune and Inflammatory Disorders Research (1 work) · Bartonella species infections research (1 work)