Andrea Loettgers
Biographic Data
| ID | 1016533 |
|---|---|
| NAME | Andrea Loettgers |
| GIVEN NAMES | Andrea |
| FAMILY NAME | Loettgers |
| SIGNATURE | LOETTGERS A |
| AFFILIATIONS | California Institute of Technology |
| ORCID | 0000-0003-1870-2345 |
| VERIFIED | Yes |
| TOTAL WORKS | 8 |
| TOTAL CITATIONS | 41 |
| AUTHOR COUNT | 8 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2007 |
| LATEST PUBLICATION YEAR | 2023 |
| H-INDEX | 4 |
Model templates
The omnipresence of the same basic equations, function forms, algorithms, and quantitative methods is one of the most spectacular characteristics of contemporary modeling practice. Recently, the emergence of the discussion of templates and template transfer has addressed this striking cross-disciplinary reach of certain mathematical forms and computational algorithms. In this paper, we develop a notion of a model template, consisting of its mathe…
(Un)Easily Possible Synthetic Biology
Synthetic biology has a strong modal dimension that is part and parcel of its engineering agenda. In turning hypothetical biological designs into actual synthetic constructs, synthetic biologists reach toward potential biology instead of concentrating on naturally evolved organisms. We analyze synthetic biology’s goal of making biology easier to engineer through the combinatorial theory of possibility, which reduces possibility to (re)combination…
Modelling as Indirect Representation? The Lotka–Volterra Model Revisited
Is there something specific about modelling that distinguishes it from many other theoretical endeavours? We consider Michael Weisberg’s ([2007], [2013]) thesis that modelling is a form of indirect representation through a close examination of the historical roots of the Lotka–Volterra model. While Weisberg discusses only Volterra’s work, we also study Lotka’s very different design of the Lotka–Volterra model. We will argue that while there are e…
Varieties of noise
Basic science through engineering? Synthetic modeling and the idea of biology-inspired engineering
Synthetic Modeling and Mechanistic Account
Recently, Bechtel and Abrahamsen have argued that mathematical models study the dynamics of mechanisms by recomposing the components and their operations into an appropriately organized system. We will study this claim through the practice of combinational modeling in circadian clock research. In combinational modeling, experiments on model organisms and mathematical/computational models are combined with a new type of model—a synthetic model. We…
How Can History of Science Matter to Scientists
History of science has developed into a methodologically diverse discipline, adding greatly to our understanding of the interplay between science, society, and culture. Along the way, one original impetus for the then newly emerging discipline--what George Sarton called the perspective "from the point of view of the scientist"--dropped out of fashion. This essay shows, by means of several examples, that reclaiming this interaction between science…
Getting Abstract Mathematical Models in Touch with Nature
Argument This article focuses on the scientific practice of a specific class of models in neuroscience and biology that approach biological systems as computational or information processing systems. This specific approach to biological systems has a long tradition that started with the information discourse in the 1940s. Borrowing concepts, methods, and techniques from cybernetics, information theory, and physics, these models are situated at th…
Modelling as Indirect Representation? The Lotka–Volterra Model Revisited
Is there something specific about modelling that distinguishes it from many other theoretical endeavours? We consider Michael Weisberg’s ([2007], [2013]) thesis that modelling is a form of indirect representation through a close examination of the historical roots of the Lotka–Volterra model. While Weisberg discusses only Volterra’s work, we also study Lotka’s very different design of the Lotka–Volterra model. We will argue that while there are e…
Basic science through engineering? Synthetic modeling and the idea of biology-inspired engineering
Varieties of noise
(Un)Easily Possible Synthetic Biology
Synthetic biology has a strong modal dimension that is part and parcel of its engineering agenda. In turning hypothetical biological designs into actual synthetic constructs, synthetic biologists reach toward potential biology instead of concentrating on naturally evolved organisms. We analyze synthetic biology’s goal of making biology easier to engineer through the combinatorial theory of possibility, which reduces possibility to (re)combination…
Synthetic Modeling and Mechanistic Account
Recently, Bechtel and Abrahamsen have argued that mathematical models study the dynamics of mechanisms by recomposing the components and their operations into an appropriately organized system. We will study this claim through the practice of combinational modeling in circadian clock research. In combinational modeling, experiments on model organisms and mathematical/computational models are combined with a new type of model—a synthetic model. We…
How Can History of Science Matter to Scientists
History of science has developed into a methodologically diverse discipline, adding greatly to our understanding of the interplay between science, society, and culture. Along the way, one original impetus for the then newly emerging discipline--what George Sarton called the perspective "from the point of view of the scientist"--dropped out of fashion. This essay shows, by means of several examples, that reclaiming this interaction between science…
Getting Abstract Mathematical Models in Touch with Nature
Argument This article focuses on the scientific practice of a specific class of models in neuroscience and biology that approach biological systems as computational or information processing systems. This specific approach to biological systems has a long tradition that started with the information discourse in the 1940s. Borrowing concepts, methods, and techniques from cybernetics, information theory, and physics, these models are situated at th…
How Can History of Science Matter to Scientists
History of science has developed into a methodologically diverse discipline, adding greatly to our understanding of the interplay between science, society, and culture. Along the way, one original impetus for the then newly emerging discipline--what George Sarton called the perspective "from the point of view of the scientist"--dropped out of fashion. This essay shows, by means of several examples, that reclaiming this interaction between science…
Basic science through engineering? Synthetic modeling and the idea of biology-inspired engineering
Synthetic Modeling and Mechanistic Account
Recently, Bechtel and Abrahamsen have argued that mathematical models study the dynamics of mechanisms by recomposing the components and their operations into an appropriately organized system. We will study this claim through the practice of combinational modeling in circadian clock research. In combinational modeling, experiments on model organisms and mathematical/computational models are combined with a new type of model—a synthetic model. We…
Varieties of noise
Modelling as Indirect Representation? The Lotka–Volterra Model Revisited
Is there something specific about modelling that distinguishes it from many other theoretical endeavours? We consider Michael Weisberg’s ([2007], [2013]) thesis that modelling is a form of indirect representation through a close examination of the historical roots of the Lotka–Volterra model. While Weisberg discusses only Volterra’s work, we also study Lotka’s very different design of the Lotka–Volterra model. We will argue that while there are e…
(Un)Easily Possible Synthetic Biology
Synthetic biology has a strong modal dimension that is part and parcel of its engineering agenda. In turning hypothetical biological designs into actual synthetic constructs, synthetic biologists reach toward potential biology instead of concentrating on naturally evolved organisms. We analyze synthetic biology’s goal of making biology easier to engineer through the combinatorial theory of possibility, which reduces possibility to (re)combination…
Model templates
The omnipresence of the same basic equations, function forms, algorithms, and quantitative methods is one of the most spectacular characteristics of contemporary modeling practice. Recently, the emergence of the discussion of templates and template transfer has addressed this striking cross-disciplinary reach of certain mathematical forms and computational algorithms. In this paper, we develop a notion of a model template, consisting of its mathe…
Computer Science (7 works) · Gene Regulatory Network Analysis (5 works) · Mathematics (5 works) · Biology (4 works) · Cognitive science (4 works) · Epistemology (4 works) · Artificial Intelligence (3 works) · Computational biology (3 works) · Engineering (3 works) · Philosophy (3 works)