Tianmei Si
Biographic Data
| ID | 10382085 |
|---|---|
| NAME | Tianmei Si |
| GIVEN NAMES | Tianmei |
| FAMILY NAME | Si |
| SIGNATURE | SI T |
| AFFILIATIONS | Peking University Sixth Hospital, Peking University Institute of Mental Health, National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), NHC Key Laboratory of Mental Health (Peking University) |
| VERIFIED | No |
| TOTAL WORKS | 7 |
| TOTAL CITATIONS | 0 |
| WORKS AS AUTHOR | 7 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 2019 |
| LATEST PUBLICATION YEAR | 2026 |
| H-INDEX | 0 |
Organ-system–based psychiatry education in undergraduate medicine
BACKGROUND: Uptake into psychiatry remains modest in many medical education systems, potentially related to limited curricular integration. We implemented an organ-system–based psychiatry module to improve relevance and engagement, evaluating medical students’ satisfaction and subsequent specialty choice. METHODS: This study was conducted in Peking University’s 8-year clinical medicine program, in which students enter directly after high school, …
Proteome-wide Mendelian randomization and colocalization analyses identify potential biomarkers for schizophrenia
This large-scale MR study provides robust evidence supporting causal roles for specific plasma proteins in SCZ pathogenesis, highlighting promising candidates for mechanistic studies and therapeutic development
Hedonic capacity in a Chinese community population sample
The Chinese version of the DARS is an effective tool for assessing hedonic capacity, i.e. screening for depression in community-dwelling populations. The observed gender differences in hedonic capacity imply that future mental health services could be more effective if adapted based on gender
Effects of aripiprazole on prolactin levels and differences in effectiveness in patients with schizophrenia
In this real-world study, for patients with acute schizophrenia, aripiprazole was effective in lowering the proportion of patients with abnormal prolactin levels, while it had no significant effect on patients with normal baseline prolactin. After adjusting for factors such as sex, age, prior antipsychotic drugs use history and disease severity, effectiveness and safety of aripiprazole in patients with normal baseline prolactin was significantly …
Dose Adjustment Model of Paliperidone in Patients With Acute Schizophrenia
This study aimed to investigate the factors that influenced the clinicians to adjust the paliperidone dose in the acute phase of schizophrenia. This was a post hoc study of an 8-week, open-label, single-arm multicenter trial which evaluated the efficacy, safety, and tolerability of flexible doses of paliperidone ER (3-12 mg/day) in patients with acutely exacerbated schizophrenia. Patients were divided into groups according to the dose at week 8 (…
Identification of Key Genes and the Pathophysiology Associated With Major Depressive Disorder Patients Based on Integrated Bioinformatics Analysis
Background: At present, laboratory blood tests to support major depressive disorder (MDD) diagnosis are not available. This study aimed to screen potential mRNAs for peripheral blood biomarkers and novel pathophysiology of MDD. Methods: The present study utilized public data from two mRNA microarray datasets to analyze the hub genes changes related to MDD. Gene Ontology (GO) analysis and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway anal…
Striatal Functional Connectivity Alterations After Two-Week Antidepressant Treatment Associated to Enduring Clinical Improvement in Major Depressive Disorder
Background: Only less than 40% of patients with Major depressive disorder (MDD) can achieve remission after several weeks of initial antidepressant treatment. Predicting whether the prescribed treatment is effective in the following course may help clinicians modify the treatment regimen in time, and reduce the staggering burden for patients and society. However, there are not yet reliable markers based on neurobiological change after a treatment…
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Striatal Functional Connectivity Alterations After Two-Week Antidepressant Treatment Associated to Enduring Clinical Improvement in Major Depressive Disorder
Background: Only less than 40% of patients with Major depressive disorder (MDD) can achieve remission after several weeks of initial antidepressant treatment. Predicting whether the prescribed treatment is effective in the following course may help clinicians modify the treatment regimen in time, and reduce the staggering burden for patients and society. However, there are not yet reliable markers based on neurobiological change after a treatment…
Identification of Key Genes and the Pathophysiology Associated With Major Depressive Disorder Patients Based on Integrated Bioinformatics Analysis
Background: At present, laboratory blood tests to support major depressive disorder (MDD) diagnosis are not available. This study aimed to screen potential mRNAs for peripheral blood biomarkers and novel pathophysiology of MDD. Methods: The present study utilized public data from two mRNA microarray datasets to analyze the hub genes changes related to MDD. Gene Ontology (GO) analysis and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway anal…
Dose Adjustment Model of Paliperidone in Patients With Acute Schizophrenia
This study aimed to investigate the factors that influenced the clinicians to adjust the paliperidone dose in the acute phase of schizophrenia. This was a post hoc study of an 8-week, open-label, single-arm multicenter trial which evaluated the efficacy, safety, and tolerability of flexible doses of paliperidone ER (3-12 mg/day) in patients with acutely exacerbated schizophrenia. Patients were divided into groups according to the dose at week 8 (…
Effects of aripiprazole on prolactin levels and differences in effectiveness in patients with schizophrenia
In this real-world study, for patients with acute schizophrenia, aripiprazole was effective in lowering the proportion of patients with abnormal prolactin levels, while it had no significant effect on patients with normal baseline prolactin. After adjusting for factors such as sex, age, prior antipsychotic drugs use history and disease severity, effectiveness and safety of aripiprazole in patients with normal baseline prolactin was significantly …
Hedonic capacity in a Chinese community population sample
The Chinese version of the DARS is an effective tool for assessing hedonic capacity, i.e. screening for depression in community-dwelling populations. The observed gender differences in hedonic capacity imply that future mental health services could be more effective if adapted based on gender
Organ-system–based psychiatry education in undergraduate medicine
BACKGROUND: Uptake into psychiatry remains modest in many medical education systems, potentially related to limited curricular integration. We implemented an organ-system–based psychiatry module to improve relevance and engagement, evaluating medical students’ satisfaction and subsequent specialty choice. METHODS: This study was conducted in Peking University’s 8-year clinical medicine program, in which students enter directly after high school, …
Proteome-wide Mendelian randomization and colocalization analyses identify potential biomarkers for schizophrenia
This large-scale MR study provides robust evidence supporting causal roles for specific plasma proteins in SCZ pathogenesis, highlighting promising candidates for mechanistic studies and therapeutic development
Internal Medicine (3 works) · Medicine (3 works) · Psychiatry (3 works) · Psychology (3 works) · Schizophrenia (object-oriented programming (3 works) · Schizophrenia research and treatment (3 works) · Genetic Associations and Epidemiology (2 works) · Mental Health Research Topics (2 works) · Post-hoc analysis (2 works) · Treatment of Major Depression (2 works)