Jennifer A Doudna

Biographic Data

ID10720517
NAMEJennifer A Doudna
GIVEN NAMESJennifer A
FAMILY NAMEDoudna
SIGNATUREDOUDNA J A
AFFILIATIONSHoward Hughes Medical Institute, Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA.
ORCID0000-0001-9161-999X
VERIFIEDNo
TOTAL WORKS3
TOTAL CITATIONS0
WORKS AS AUTHOR3
WORKS AS EDITOR0
FIRST PUBLICATION YEAR2012
LATEST PUBLICATION YEAR2015
H-INDEX0

  • A prudent path forward for genomic engineering and germline gene modification

    Open AccessDavid Baltimore, Paul Berg et al.ARTICLEScience2015

    A framework for open discourse on the use of CRISPR-Cas9 technology to manipulate the human genome is urgently needed

  • The new frontier of genome engineering with CRISPR-Cas9

    Open AccessJennifer A Doudna, Emmanuelle CharpentierARTICLEScience2014

    The advent of facile genome engineering using the bacterial RNA-guided CRISPR-Cas9 system in animals and plants is transforming biology. We review the history of CRISPR (clustered regularly interspaced palindromic repeat) biology from its initial discovery through the elucidation of the CRISPR-Cas9 enzyme mechanism, which has set the stage for remarkable developments using this technology to modify, regulate, or mark genomic loci in a wide variet…

  • A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity

    Open AccessMartin Jinek, Krzysztof Chylinski et al.ARTICLEScience2012

    Ditching Invading DNA Bacteria and archaea protect themselves from invasive foreign nucleic acids through an RNA-mediated adaptive immune system called CRISPR (clustered regularly interspaced short palindromic repeats)/CRISPR-associated (Cas). Jinek et al. (p. 816 , published online 28 June; see the Perspective by Brouns ) found that for the type II CRISPR/Cas system, the CRISPR RNA (crRNA) as well as the trans-activating crRNA—which is known to …