L Christie Rockwell
Biographic Data
| ID | 108040 |
|---|---|
| NAME | L Christie Rockwell |
| GIVEN NAMES | L Christie |
| FAMILY NAME | Rockwell |
| SIGNATURE | ROCKWELL L C |
| AFFILIATIONS | Temple University |
| VERIFIED | No |
| TOTAL WORKS | 6 |
| TOTAL CITATIONS | 11 |
| AUTHOR COUNT | 6 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2003 |
| LATEST PUBLICATION YEAR | 2015 |
| H-INDEX | 1 |
CYP17 genotype modifies the impact of anthropometric variation on salivary estradiol in healthy women
Several studies demonstrate that human ovarian function is responsive to the energetic environment, which has led to the development of theoretical models that explain this phenomenon. Although many genes are involved in ovarian hormone production, the possibility that genetic polymorphism may affect ovarian response to energetic conditions has not been considered. Cytochrome P450c17α is an enzyme that produces androgen precursors used to make es…
Gene x environment interactions impact endometrial function and the menstrual cycle
OBJECTIVES: We assessed the impact of a high frequency, functionally significant allelic variant of the progesterone receptor gene (PROGINS) on endometrial function and menstrual cycle characteristics. Further we asked whether PROGINS moderates the impact of life history characteristics, anthropometric measures, and physical activity on endometrial function. METHODS: Fifty-two women were genotyped for the PROGINS variant, provided life history in…
Worldwide distribution of allelic variation at the progesterone receptor locus and the incidence of female reproductive cancers
OBJECTIVES: Global patterns of the incidence of cancer are often attributed to environmental and lifestyle differences between regions. Less attention has been given to global patterns of allelic variation of genes that may contribute to the risk of developing cancer. METHODS: We genotyped samples from 21 populations for four variants of the progesterone receptor (PR) gene. One is an Alu insertion in intron 7 which defines the PROGINS haplotype. …
Grandmotherhood
Grandmotherhood
Grandmotherhood: The Evolutionary Significance of the Second Half of Female Life. Eckart Voland, Athanasios Chasiotis, and Wulf Schiefenhövel, eds. New Brunswick: Rutgers University Press, 2005. 314 pp
Human physiological adaptation to pregnancy
Reproductive success requires successful maternal physiological adaptation to pregnancy. An interspecific perspective reveals that the human species has modified features of our haplorhine heritage affecting the uteroplacental circulation. We speculate that such modifications — including early implantation and deep, widespread invasion of fetal (trophoblast cells) into and resultant remodeling of maternal uterine vessels — are responses to or com…
Grandmotherhood
Grandmotherhood: The Evolutionary Significance of the Second Half of Female Life. Eckart Voland, Athanasios Chasiotis, and Wulf Schiefenhövel, eds. New Brunswick: Rutgers University Press, 2005. 314 pp
Grandmotherhood
Human physiological adaptation to pregnancy
Reproductive success requires successful maternal physiological adaptation to pregnancy. An interspecific perspective reveals that the human species has modified features of our haplorhine heritage affecting the uteroplacental circulation. We speculate that such modifications — including early implantation and deep, widespread invasion of fetal (trophoblast cells) into and resultant remodeling of maternal uterine vessels — are responses to or com…
Grandmotherhood
Grandmotherhood
Grandmotherhood: The Evolutionary Significance of the Second Half of Female Life. Eckart Voland, Athanasios Chasiotis, and Wulf Schiefenhövel, eds. New Brunswick: Rutgers University Press, 2005. 314 pp
Worldwide distribution of allelic variation at the progesterone receptor locus and the incidence of female reproductive cancers
OBJECTIVES: Global patterns of the incidence of cancer are often attributed to environmental and lifestyle differences between regions. Less attention has been given to global patterns of allelic variation of genes that may contribute to the risk of developing cancer. METHODS: We genotyped samples from 21 populations for four variants of the progesterone receptor (PR) gene. One is an Alu insertion in intron 7 which defines the PROGINS haplotype. …
Gene x environment interactions impact endometrial function and the menstrual cycle
OBJECTIVES: We assessed the impact of a high frequency, functionally significant allelic variant of the progesterone receptor gene (PROGINS) on endometrial function and menstrual cycle characteristics. Further we asked whether PROGINS moderates the impact of life history characteristics, anthropometric measures, and physical activity on endometrial function. METHODS: Fifty-two women were genotyped for the PROGINS variant, provided life history in…
CYP17 genotype modifies the impact of anthropometric variation on salivary estradiol in healthy women
Several studies demonstrate that human ovarian function is responsive to the energetic environment, which has led to the development of theoretical models that explain this phenomenon. Although many genes are involved in ovarian hormone production, the possibility that genetic polymorphism may affect ovarian response to energetic conditions has not been considered. Cytochrome P450c17α is an enzyme that produces androgen precursors used to make es…
Biology (4 works) · Medicine (4 works) · Demography (3 works) · Genetics (3 works) · Anthropometry (2 works) · Demography (2 works) · Endocrinology (2 works) · Estrogen and related hormone effects (2 works) · Gene (2 works) · Genetic variation (2 works)