Thayse Gomes
Biographic Data
| ID | 110661 |
|---|---|
| NAME | Thayse Gomes |
| GIVEN NAMES | Thayse |
| FAMILY NAME | Gomes |
| SIGNATURE | GOMES T |
| AFFILIATIONS | St. Michael's Hospital |
| ORCID | 0000-0002-1468-1965 |
| VERIFIED | Yes |
| TOTAL WORKS | 30 |
| TOTAL CITATIONS | 4 |
| AUTHOR COUNT | 30 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2009 |
| LATEST PUBLICATION YEAR | 2026 |
| H-INDEX | 1 |
Effect of the Covid-19 pandemic on initiations of opioid agonist therapy in Ontario: A population-based interrupted time series analysis
BACKGROUND: Maintaining access to opioid agonist therapy (OAT) was a key concern at the COVID-19 pandemic onset. Consequently, Ontario introduced guidance for changes to OAT delivery, including relaxed take-home dosing and expanded virtual care. We examined how the pandemic influenced OAT initiation trends. METHODS: We conducted a population-based, retrospective interrupted time series analysis using linked administrative health data from March 2…
The short-term impacts of the decriminalization of personal possession of select illegal drugs on drug possession criminal incidents and criminal cases in British Columbia, Canada (2013 to 2023)
Safer opioid supply initiation among First Nations Peoples in Ontario, Canada, 2019 to 2023
Overall, the rate of First Nations Peoples accessing SOS in Ontario increased almost five-fold, demonstrating growing engagement with this harm reduction approach. Future research is needed to understand First Nations People's experiences with SOS, and the impacts of program closures across Canada
Trends in varying modes of drug use in opioid toxicity deaths in Ontario from 2017 to 2021
Changing trends in safer opioid supply uptake, dose and hydromorphone volume in Ontario: A population-based cross-sectional study
An accelerating number of safer opioid supply recipients over time, coupled with rising immediate-release hydromorphone doses likely reflects efforts to meet the needs of people who use drugs in the context of an increasingly potent unregulated opioid supply, particularly as this supply changed throughout the COVID-19 pandemic
Assessing the impact of the introduction of generic methadone to the Ontario public drug formulary
Our findings did not indicate broad treatment destabilization or increased opioid-related toxicity among methadone recipients in the months following the introduction of generic products. Early notification of formulary changes, phased implementation of the policy, as well as information resources developed for patients and clinicians may have played a role in mitigating potential disruptions for this population
Trends in the dispensing of opioids for pain and concurrent benzodiazepine use among First Nations People in Ontario, Canada, from 2013 to 2021
Opioid analgesic prescribing patterns for First Nations People living in Ontario indicate a decrease in both overall prescribing rates and concurrent benzodiazepine use
Complex decision-making of people's use of opioid agonist therapy during pregnancy: Troubling the concept of 'non-compliance
Clinical guidelines strongly recommend that pregnant people with opioid use disorder be offered Opioid Agonist Therapy (OAT); however, access to and retention in substance use services are influenced by a multitude of factors. We conducted 25 semi-structured qualitative interviews with pregnant and recently pregnant people who used opioids or OAT before their pregnancy. Participants were recruited from various health and social services, through …
The decriminalization of illicit drugs in British Columbia: A national evaluation protocol
This evaluation will draw on implementation science research practices to evaluate and understand the full impacts of this novel drug policy experiment. Results will be widely disseminated through manuscripts, reports, presentations, and infographics, which will be adapted and tailored for specific audiences. The protocol identifies several anticipated challenges and limitations. This evaluation's evidence-based findings will be poised to offer p…
Trends in opioid toxicities among people with and without opioid use disorder and the impact of the Covid-19 pandemic in Ontario, Canada: A population-based analysis
The rate of opioid toxicities accelerated across Ontario following the pandemic-related state of emergency, with the majority of this increase among people with OUD. The important differences observed among people with OUD compared with those without, highlights the critical need for improved access to harm reduction and treatment interventions among this population
Prescribed safer opioid supply: A scoping review of the evidence
BACKGROUND: Safer opioid supply programs provide prescription pharmaceutical opioids, often with supportive services, to people at high risk of experiencing harms related to substance use. However, questions regarding the effectiveness and safety of this practice remain. We conducted a scoping review of literature describing client outcomes from formal opioid supply programs providing prescriptions for pharmaceutical opioids, and the perceptions …
Effect of Free Medicine Distribution on Health Care Costs in Canada Over 3 Years: A Secondary Analysis of the CLEAN Meds Randomized Clinical Trial
ClinicalTrials.gov Identifier: NCT02744963
Adherence to antipsychotic laboratory monitoring guidelines in children and youth: A population-based study
Most children initiating antipsychotic therapy do not receive guideline-recommended metabolic laboratory monitoring. Further research is needed to understand reasons for poor guideline adherence and the role of clinician training and collaborative service models in promoting best monitoring practices
A Preliminary Assessment of Short-Term Social and Substance Use-Related Outcomes Among Clients of Integrated Safer Opioid Supply Pilot Programs in Toronto, Canada
The online version contains supplementary material available at 10.1007/s11469-023-01219-3
Accessing hepatitis C direct acting antivirals among people living with hepatitis C: A qualitative study
Despite the availability of curative therapies, access to such treatment for people who inject drugs is limited by stigma enacted in and structured within healthcare encounters. Developing novel, low-threshold delivery programs that remove power differentials and attend to the social and structural determinants of health and reinfection are needed to facilitate further scale up of DAAs and support the goal of eradicating hepatitis C as a public h…
Geographic variation and sociodemographic correlates of prescription psychotropic drug use among children and youth in Ontario, Canada: A population-based study
We found significant variation in psychotropic dispensing among young Ontarians. Targeted investment in regions with long wait times for publicly-funded non-pharmacological interventions and novel collaborative service models may minimize variability and promote best practices in using psychotropics among children and youth
Challenges of implementing safer supply programs in Canada during the Covid-19 pandemic: A qualitative analysis
Safer supply pilot programs in Canada face multiple inner and outer implementation challenges. Given the potential role of safer supply programs in addressing the drug toxicity crisis in Canada and the possibility of future scale-up, services should be well-supported during their implementation phases. Refining service provision within safer supply programs based on the feedback and experiences of clients and program administrators is warranted, …
Assessing the impact of the slow-release oral morphine drug shortages in Ontario, Canada: A population-based time series analysis
The epidemiology of benzodiazepine-related toxicity in Ontario, Canada: A population-based descriptive study
Benzodiazepine-related toxicity has declined in Ontario overall, but has increased among youth and young adults. Furthermore, there is growing co-involvement of opioids, stimulants, and alcohol, which may reflect the recent emergence of benzodiazepines in the unregulated drug supply. Multifaceted public health initiatives comprising harm reduction, mental health supports, and promotion of appropriate prescribing are needed to reduce benzodiazepin…
Impact of the Covid-19 pandemic on the provision of take-home doses of opioid agonist therapy in Ontario, Canada: A population-based time-series analysis
Evaluating interventions to facilitate opioid agonist treatment access among people who inject drugs in Toronto, Ontario during Covid-19 pandemic restrictions
Characterizing safer supply prescribing of immediate release hydromorphone for individuals with opioid use disorder across Ontario, Canada
A qualitative study of a publicly funded pharmacy-dispensed naloxone program
Despite increasing the availability of naloxone, participants characterized several social and environmental factors that could limit the accessibility of the drug from pharmacies. Strategies to address these factors could create enabling environments within pharmacies that optimize the reach and impact of pharmacy-dispensed naloxone
Trends in HIV pre-exposure prophylaxis uptake in Ontario, Canada, and impact of policy changes: A population-based analysis of projected pharmacy data (2015–2018)
PrEP use has risen in Ontario in association with favourable policy changes, but remains far below guideline recommendations
Like being put on an ice floe and shoved away”: A qualitative study of the impacts of opioid-related policy changes on people who take opioids
The introduction of opioid-related policies had unintended consequences for people who take opioids. Potential measures for mitigating these consequences include ensuring that people who take opioids are involved in all facets of policy development and implementation, integrating peer workers into the care of these individuals, and respecting patient agency when decisions about pain management and opioid use are made
Trends in HIV pre-exposure prophylaxis uptake in Ontario, Canada, and impact of policy changes: A population-based analysis of projected pharmacy data (2015–2018)
PrEP use has risen in Ontario in association with favourable policy changes, but remains far below guideline recommendations
Health status utilities and the impact of pressure ulcers in long-term care residents in Ontario
LTC residents with PU had slightly though statistically significantly lower HRQOL than those without PU. Comorbidity contributed substantially to the low HRQOL in these populations. Community-weighted MDS-HSI utilities for LTC residents are useful for cost-effectiveness analyses and help guide health policy development
Risk of overdose and death following codeine prescription among immigrants
BACKGROUND: Immigrants may be at a higher risk of adverse drug reactions, in that poor language proficiency reduces individuals understanding of drug label instructions. Additionally, there are reports of severe or fatal toxicity due to CYP2D6 ultrarapid hepatic metabolism of codeine to morphine among some ethnic groups, especially those from Eastern Africa. METHODS: Between 2002 and 2012 we conducted a population-based cohort study among residen…
The impact of policies to reduce blood glucose test strip utilization and costs in Canada
Modeling longitudinal changes in hypertensive and waist phenotype: The oporto growth, health, and performance study
OBJECTIVES: This study aimed to: (1) model changes in the hypertensive and waist phenotype (HWP) in youth, and (2) investigate the effects of sex, biological maturation, total physical activity (TPA), and physical fitness (PF) in HWP trajectories. METHODS: Data were obtained annually for 3 years from the Oporto Growth, Health, and Performance Study, and comprised 5,549 adolescents (2,732 girls) divided into four age cohorts (10, 12, 14, and 16 ye…
Like being put on an ice floe and shoved away”: A qualitative study of the impacts of opioid-related policy changes on people who take opioids
The introduction of opioid-related policies had unintended consequences for people who take opioids. Potential measures for mitigating these consequences include ensuring that people who take opioids are involved in all facets of policy development and implementation, integrating peer workers into the care of these individuals, and respecting patient agency when decisions about pain management and opioid use are made
Evaluation of the fentanyl patch-for-patch program in Ontario, Canada
Trends in HIV pre-exposure prophylaxis uptake in Ontario, Canada, and impact of policy changes: A population-based analysis of projected pharmacy data (2015–2018)
PrEP use has risen in Ontario in association with favourable policy changes, but remains far below guideline recommendations
A qualitative study of a publicly funded pharmacy-dispensed naloxone program
Despite increasing the availability of naloxone, participants characterized several social and environmental factors that could limit the accessibility of the drug from pharmacies. Strategies to address these factors could create enabling environments within pharmacies that optimize the reach and impact of pharmacy-dispensed naloxone
Impact of the Covid-19 pandemic on the provision of take-home doses of opioid agonist therapy in Ontario, Canada: A population-based time-series analysis
Evaluating interventions to facilitate opioid agonist treatment access among people who inject drugs in Toronto, Ontario during Covid-19 pandemic restrictions
Characterizing safer supply prescribing of immediate release hydromorphone for individuals with opioid use disorder across Ontario, Canada
Effect of Free Medicine Distribution on Health Care Costs in Canada Over 3 Years: A Secondary Analysis of the CLEAN Meds Randomized Clinical Trial
ClinicalTrials.gov Identifier: NCT02744963
Adherence to antipsychotic laboratory monitoring guidelines in children and youth: A population-based study
Most children initiating antipsychotic therapy do not receive guideline-recommended metabolic laboratory monitoring. Further research is needed to understand reasons for poor guideline adherence and the role of clinician training and collaborative service models in promoting best monitoring practices
A Preliminary Assessment of Short-Term Social and Substance Use-Related Outcomes Among Clients of Integrated Safer Opioid Supply Pilot Programs in Toronto, Canada
The online version contains supplementary material available at 10.1007/s11469-023-01219-3
Accessing hepatitis C direct acting antivirals among people living with hepatitis C: A qualitative study
Despite the availability of curative therapies, access to such treatment for people who inject drugs is limited by stigma enacted in and structured within healthcare encounters. Developing novel, low-threshold delivery programs that remove power differentials and attend to the social and structural determinants of health and reinfection are needed to facilitate further scale up of DAAs and support the goal of eradicating hepatitis C as a public h…
Geographic variation and sociodemographic correlates of prescription psychotropic drug use among children and youth in Ontario, Canada: A population-based study
We found significant variation in psychotropic dispensing among young Ontarians. Targeted investment in regions with long wait times for publicly-funded non-pharmacological interventions and novel collaborative service models may minimize variability and promote best practices in using psychotropics among children and youth
Challenges of implementing safer supply programs in Canada during the Covid-19 pandemic: A qualitative analysis
Safer supply pilot programs in Canada face multiple inner and outer implementation challenges. Given the potential role of safer supply programs in addressing the drug toxicity crisis in Canada and the possibility of future scale-up, services should be well-supported during their implementation phases. Refining service provision within safer supply programs based on the feedback and experiences of clients and program administrators is warranted, …
Assessing the impact of the slow-release oral morphine drug shortages in Ontario, Canada: A population-based time series analysis
The epidemiology of benzodiazepine-related toxicity in Ontario, Canada: A population-based descriptive study
Benzodiazepine-related toxicity has declined in Ontario overall, but has increased among youth and young adults. Furthermore, there is growing co-involvement of opioids, stimulants, and alcohol, which may reflect the recent emergence of benzodiazepines in the unregulated drug supply. Multifaceted public health initiatives comprising harm reduction, mental health supports, and promotion of appropriate prescribing are needed to reduce benzodiazepin…
The decriminalization of illicit drugs in British Columbia: A national evaluation protocol
This evaluation will draw on implementation science research practices to evaluate and understand the full impacts of this novel drug policy experiment. Results will be widely disseminated through manuscripts, reports, presentations, and infographics, which will be adapted and tailored for specific audiences. The protocol identifies several anticipated challenges and limitations. This evaluation's evidence-based findings will be poised to offer p…
Trends in opioid toxicities among people with and without opioid use disorder and the impact of the Covid-19 pandemic in Ontario, Canada: A population-based analysis
The rate of opioid toxicities accelerated across Ontario following the pandemic-related state of emergency, with the majority of this increase among people with OUD. The important differences observed among people with OUD compared with those without, highlights the critical need for improved access to harm reduction and treatment interventions among this population
Prescribed safer opioid supply: A scoping review of the evidence
BACKGROUND: Safer opioid supply programs provide prescription pharmaceutical opioids, often with supportive services, to people at high risk of experiencing harms related to substance use. However, questions regarding the effectiveness and safety of this practice remain. We conducted a scoping review of literature describing client outcomes from formal opioid supply programs providing prescriptions for pharmaceutical opioids, and the perceptions …
Trends in varying modes of drug use in opioid toxicity deaths in Ontario from 2017 to 2021
Changing trends in safer opioid supply uptake, dose and hydromorphone volume in Ontario: A population-based cross-sectional study
An accelerating number of safer opioid supply recipients over time, coupled with rising immediate-release hydromorphone doses likely reflects efforts to meet the needs of people who use drugs in the context of an increasingly potent unregulated opioid supply, particularly as this supply changed throughout the COVID-19 pandemic
Assessing the impact of the introduction of generic methadone to the Ontario public drug formulary
Our findings did not indicate broad treatment destabilization or increased opioid-related toxicity among methadone recipients in the months following the introduction of generic products. Early notification of formulary changes, phased implementation of the policy, as well as information resources developed for patients and clinicians may have played a role in mitigating potential disruptions for this population
Medicine (27 works) · Opioid Use Disorder Treatment (22 works) · Environmental health (18 works) · Opioid (16 works) · Internal Medicine (15 works) · Population (14 works) · HIV, Drug Use, Sexual Risk (13 works) · Psychiatry (13 works) · Nursing (9 works) · Emergency Medicine (7 works)