Dorairaj Prabhakaran
Biographic Data
| ID | 112157 |
|---|---|
| NAME | Dorairaj Prabhakaran |
| GIVEN NAMES | Dorairaj |
| FAMILY NAME | Prabhakaran |
| SIGNATURE | PRABHAKARAN D |
| AFFILIATIONS | Centre for Chronic Disease Control |
| ORCID | 0000-0002-3172-834X |
| VERIFIED | Yes |
| TOTAL WORKS | 77 |
| TOTAL CITATIONS | 17 |
| AUTHOR COUNT | 77 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2002 |
| LATEST PUBLICATION YEAR | 2025 |
| H-INDEX | 2 |
Does home-based screening improve hypertension diagnosis, treatment and control? A regression discontinuity analysis in urban India
As part of India’s efforts to expand primary healthcare services, several state governments are implementing or considering home-based hypertension screening programmes to improve population-wide diagnosis and blood pressure (BP) control rates. However, there is limited evidence on the effectiveness of home-based screening programmes in India. Using six waves of population-representative cohort data (N=15574), we estimate the causal effect of a h…
Co-creating community engagement and involvement strategies
Living with multiple long-term conditions (MLTCs) presents significant healthcare and patient-level challenges, which are further compounded by fragmented and poorly coordinated healthcare systems, leading to difficulties in access, dissatisfaction with quality of services, non-engagement with treatment protocols and poor outcomes. Overcoming these barriers requires a strong and equitable primary healthcare system that prioritises people-centred …
Does health insurance coverage improve cardiometabolic risk factor levels? Quasi-experimental evidence from India
Background Chronic conditions cause notable health and economic burdens. While health insurance enables access to healthcare, its effects on chronic care outcomes remain under-explored.Objective To examine the association between health insurance coverage and cardiometabolic risk factors among people with chronic conditions in India.Methods Data from the Centre for Cardiometabolic Risk Reduction in South Asia (CARRS) and Solan studies, including …
The role of neighborhood and household level socio-economic status in determining air pollution exposure in two Indian cities
Although recent studies indicate that air pollution exposure affects lower socioeconomic groups more, there is limited evidence regarding the relative influence of household and neighborhood socioeconomic status (SES) on air pollution exposure in lower- and middle-income country settings. We evaluated the associations between neighborhood- and household-level SES metrics and exposure to ambient particulate matter (PM 2.5 ) in two populous Indian …
The maternal and newborn health eCohort to track longitudinal care quality
The MNH eCohort was developed to fill gaps in maternal and newborn health (MNH) care quality measurement. In this paper, we describe the survey development process, recruitment strategy, data collection procedures, survey content and plans for analysis of the data generated by the study. We also compare the survey content to that of existing multi-country tools on MNH care quality. The eCohort is a longitudinal mixed-mode (in-person and phone) su…
Methods and participant characteristics in the Cancer Risk in Vegetarians Consortium
Food intakes and lifestyle factors of both non-vegetarians and vegetarians varied markedly across the individual cohorts, which may be due to differences in both culture and socioeconomic status, as well as differences in questionnaire design. Therefore, care is needed in the interpretation of the impacts of vegetarian diets on cancer risk
Doubling Farmers’ Incomes in India by 2022
In 2016–2017, Indian government set a policy target of doubling farmers’ incomes by 2022. This article investigates farmers’ perspectives on this contentious policy. Results suggest that only 18% of farmers were aware of this policy. Most farmers blamed the government’s support, high cost of cultivation and low MSP for their inability to increase their farm profitability. While synthesizing farmers’ perspectives, past trends, and the debate among…
Evaluating bias with loss to follow-up in a community-based cohort
BACKGROUND: Retention of participants is a challenge in community-based longitudinal cohort studies. We aim to evaluate the factors associated with loss to follow-up and estimate attrition bias. METHODS: Data are from an ongoing cohort study, Center for cArdiometabolic Risk Reduction in South Asia (CARRS) in India (Delhi and Chennai). Multinomial logistic regression analysis was used to identify sociodemographic factors associated with partial (a…
Epidemiological pattern of Covid-19 and its association with periodontal health in an urban Indian cohort
Background Studies have highlighted a possible influence of gingival and periodontal disease (PD) on COVID-19 risk and severity. However, the evidence is based on hospital-based studies and community-level data are sparse. Objectives We described the epidemiological pattern of SARS-CoV-2 infection in Delhi and evaluated the associations of gingival and PD with incident COVID-19 disease in a regionally representative urban Indian population. Metho…
Couple concordance in diabetes, hypertension and dyslipidaemia in urban India and Pakistan and associated socioeconomic and household characteristics and modifiable risk factors
BACKGROUND: Concordance in chronic disease status has been observed within couples. In urban India and Pakistan, little is known about couple concordance in diabetes, hypertension, and dyslipidaemia and associated socioeconomic characteristics and modifiable risk factors. METHODS: We analysed cross-sectional data from 2548 couples from the Centre for cArdio-metabolic Risk Reduction in South Asia cohort in Chennai, Delhi and Karachi. We estimated …
Patterns of multimorbidity in India
There is a dearth of evidence on the epidemiology of multimorbidity in low- and middle-income countries. This study aimed to determine the prevalence of multimorbidity in India and its variation among states and population groups. We analyzed data from a nationally representative household survey conducted in 2015–2016 among individuals aged 15 to 49 years. Multimorbidity was defined as having two or more conditions out of five common chronic mor…
Effect modification by sex for associations of fine particulate matter (PM 2.5 ) with cardiovascular mortality, hospitalization, and emergency room visits
Particulate matter with aerodynamic diameter no larger than 2.5 μm (PM 2.5 ) has been linked to cardiovascular diseases (CVDs) but evidence for vulnerability by sex remains unclear. We performed systematic review and meta-analysis to synthesize the state of scientific evidence on whether cardiovascular risks from PM 2.5 differ for men compared to women. The databases Pubmed, Scopus, Embase, and GreenFILE were searched for studies published Jan. 1…
Anxiety and depression among adult tobacco users during the Covid-19 restrictions in India
During COVID-19 lockdown, mental health of tobacco users (primarily women) was associated with food, housing and financial insecurity. The Indian Government rightly initiated several health, social and economic measures to shield the most vulnerable from COVID-19, including a ban on the sale of tobacco products. It is also necessary to prioritize universal health coverage, expanded social security net, tobacco cessation and mental health services…
Feasibility Trial of Yoga Programme for Type 2 Diabetes Prevention (Yoga-DP) among High-Risk People in India
Yoga-based interventions can be effective in preventing type 2 diabetes mellitus (T2DM). We developed a Yoga programme for T2DM prevention (YOGA-DP) and conducted a feasibility randomised controlled trial (RCT) among high-risk people in India. This qualitative study's objective was to identify and explore participants' trial- and intervention-related barriers and facilitators. The feasibility trial was conducted at two Yoga centres in New Delhi a…
Infant Young Child Feeding Practices in an Indian Maternal–Child Birth Cohort in Belagavi, Karnataka
Poor infant young child feeding (IYCF) practices result in malnutrition, poor psychosocial development, poor school performance and less productivity in later life, thereby perpetuating a vicious cycle. The current study aims to characterize the IYCF practices during the first year of life in a maternal-child birth cohort (DHANI) in Belagavi, Karnataka, India. We collected data from the dyad at birth, 6 and 12 months postpartum. We examined dieta…
Burden, patterns, and impact of multimorbidity in North India
The burden of multimorbidity was high in this young rural population, which portends significant adverse effects on their health and quality of life. The Indian health system should be reconfigured to address this emerging health priority holistically, by adopting a more integrated and sustainable model of care
The role of dairy in healthy and sustainable food systems
Moderate milk-producing states such as Andhra Pradesh will continue to develop their dairy industry through policy actions. Including communities in policy discussions through innovative methods like Photovoice can help to maximise the positive and minimise the negative role of dairy in evolving local food systems
Health and economic impact of air pollution in the states of India
BACKGROUND: The association of air pollution with multiple adverse health outcomes is becoming well established, but its negative economic impact is less well appreciated. It is important to elucidate this impact for the states of India. METHODS: We estimated exposure to ambient particulate matter pollution, household air pollution, and ambient ozone pollution, and their attributable deaths and disability-adjusted life-years in every state of Ind…
Yoga Program for Type 2 Diabetes Prevention (Yoga-DP) Among High-Risk People
Background: Yoga-based interventions can be effective in preventing type 2 diabetes mellitus (T2DM). We developed a Yoga program for T2DM prevention (YOGA-DP) among high-risk people and conducted a feasibility randomized controlled trial (RCT) in India. The objective of this study was to identify and explore why potential participants declined to participate in the feasibility RCT. Methods: An exploratory qualitative study, using semi-structured …
Health, psychosocial, and economic impacts of the Covid-19 pandemic on people with chronic conditions in India
People with chronic conditions, particularly among poor, rural, and marginalized populations, have experienced difficulties in accessing healthcare and been severely affected both socially and financially by the COVID-19 pandemic
A Photovoice Study to Reveal Community Perceptions of Highly Processed Packaged Foods in India
India is experiencing a nutrition transition, with sales of packaged and processed foods rapidly increasing in recent years. This study sought to understand the views and experiences of self-help groups about highly processed, packaged food in Visakhapatnam, India, using the Photovoice method. Participants were able to record, reflect on and critique their environments through participatory analysis, identifying key themes, and offering a critica…
International Society of Hypertension Global Hypertension Practice Guidelines
Context and Purpose of This Guideline \nStatement of Remit \nTo align with its mission to reduce the global burden of raised \nblood pressure (BP), the International Society of Hypertension \n(ISH) has developed worldwide practice guidelines for the \nmanagement of hypertension in adults, aged 18 years and \nolder. \nThe ISH Guidelines Committee extracted evidence-based \ncontent presented in recently published extensively reviewed \nguidelines a…
Development of a Yoga Program for Type-2 Diabetes Prevention (Yoga-DP) Among High-Risk People in India
Introduction Many Indians are at high-risk of type-2 diabetes mellitus (T2DM). Yoga is an ancient Indian mind-body discipline, that has been associated with improved glucose levels and can help to prevent T2DM. The study aimed to systematically develop a Yoga programme for T2DM prevention (YOGA-DP) among high-risk people in India using a complex intervention development approach. Materials and methods As part of the intervention, we developed a b…
Potentially Heterogeneous Cross-Sectional Associations of Seafood Consumption with Diabetes and Glycemia in Urban South Asia
Aims : In this study, we aimed to estimate cross-sectional associations of fish or shellfish consumption with diabetes and glycemia in three South Asian mega-cities. Methods : We analyzed baseline data from 2010-2011 of a cohort ( n = 16,287) representing the population ≥20 years old that was neither pregnant nor on bedrest from Karachi (unweighted n = 4017), Delhi (unweighted n = 5364), and Chennai (unweighted n = 6906). Diabetes was defined as …
The impact of air pollution on deaths, disease burden, and life expectancy across the states of India
Background Air pollution is a major planetary health risk, with India estimated to have some of the worst levels globally. To inform action at subnational levels in India, we estimated the exposure to air pollution and its impact on deaths, disease burden, and life expectancy in every state of India in 2017. Methods We estimated exposure to air pollution, including ambient particulate matter pollution, defined as the annual average gridded concen…
Stress and diabetes in socioeconomic context
Park availability and major depression in individuals with chronic conditions
Green space exposure has been positively correlated with better mental-health indicators in several high income countries, but has not been examined in low- and middle-income countries undergoing rapid urbanization. Building on a study of mental health in adults with a pre-existing chronic condition, we examined the association between park availability and major depression among 1208 adults surveyed in Delhi, India. Major depression was measured…
Couple concordance in diabetes, hypertension and dyslipidaemia in urban India and Pakistan and associated socioeconomic and household characteristics and modifiable risk factors
BACKGROUND: Concordance in chronic disease status has been observed within couples. In urban India and Pakistan, little is known about couple concordance in diabetes, hypertension, and dyslipidaemia and associated socioeconomic characteristics and modifiable risk factors. METHODS: We analysed cross-sectional data from 2548 couples from the Centre for cArdio-metabolic Risk Reduction in South Asia cohort in Chennai, Delhi and Karachi. We estimated …
Designing programs to improve diets for maternal and child health
Improving maternal and child nutrition in resource-poor settings requires effective use of limited resources, but priority-setting is constrained by limited information about program costs and impacts, especially for interventions designed to improve diet quality. This study utilized a mixed methods approach to identify, describe and estimate the potential costs and impacts on child dietary intake of 12 nutrition-sensitive programs in Ethiopia, N…
Tobacco and Alcohol Use Outcomes of a School-based Intervention in New Delhi
The project had a significant impact on tobacco use
Bidi and cigarette smoking and risk of acute myocardial infarction among males in urban India
Death from myocardial infarction (MI) in India is exacerbated by smoking of bidis or cigarettes. Smoking among 309 men with incident MI was compared to 618 age matched controls; 56% of the individuals with MI and 26% of controls were current smokers. Current smokers had a relative risk of 4.7 (95% confidence interval (CI) 3.2 to 6.9) compared to never smokers. Relative risks for smoking more than 10 cigarettes or 10 bidis daily were 9.1 (95% CI 4…
The Effect of Rural-to-Urban Migration on Obesity and Diabetes in India
BACKGROUND: Migration from rural areas of India contributes to urbanisation and may increase the risk of obesity and diabetes. We tested the hypotheses that rural-to-urban migrants have a higher prevalence of obesity and diabetes than rural nonmigrants, that migrants would have an intermediate prevalence of obesity and diabetes compared with life-long urban and rural dwellers, and that longer time since migration would be associated with a higher…
Assessment of physical activity using accelerometry, an activity diary, the heart rate method and the Indian Migration Study questionnaire in South Indian adults
Objective To validate questionnaire-based physical activity level (PAL) against accelerometry and a 24 h physical activity diary (24 h AD) as reference methods (Protocol 2), after validating these reference methods against the heart rate–oxygen consumption (HRVO 2 ) method (Protocol 1). Design Cross-sectional study. Setting Two villages in Andhra Pradesh state and Bangalore city, South India. Subjects Ninety-four participants (fifty males, forty-…
Effects of migration on food consumption patterns in a sample of Indian factory workers and their families
Objectives To study the impact of migration on food consumption among Indian factory workers and their siblings and spouses. Design A cross-sectional study was conducted to assess diet using an interviewer-administered semi-quantitative FFQ from which intake of 184 commonly consumed food items was obtained. Settings Participants recruited from factory sites in Bangalore, Lucknow, Nagpur and Hyderabad. Subjects The sample comprised 7049 participan…
Multi-center feasibility study evaluating recruitment, variability in risk factors and biomarkers for a diet and cancer cohort in India
A high percentage of participants complied with study procedures including biological sample collection. Epidemiologic expertise and sufficient infrastructure exists at these three sites in India to successfully carry out a modest sized population-based study; however, we identified some potential problems in conducting a cohort study, such as limited number of facilities to handle biological samples
P2-128 Distribution of 10-year and lifetime predicted risk for cardiovascular disease in the Indian sentinel surveillance study population
Introduction Cardiovascular disease (CVD) prevention guidelines recommend lifetime risk stratification for primary prevention of CVD, but no such risk stratification has been performed in India to date. Methods We estimated short-term and lifetime predicted CVD risk among 10 054 disease free, adult Indians in the age group of 20-69 years who participated in a nationwide risk factor surveillance study. The study population was then stratified into…
P2-295 Socio-demographic patterns of physical activity in India
Introduction The existence of a socio-demographic patterns of cardiovascular disease (CVD) in India has been suggested, with a higher CVD risk in individuals: from urban areas, the south, higher socio-economic status (SES), and in the elderly. Whether this pattern is replicated in physical activity (PA) is unknown. We aimed to examine the socio-demographic pattern of PA in India using the Indian Migration Study (IMS); a cross-sectional sib-pair d…
O6-1.1 The global status of epidemiology
To take stock of the current status of epidemiology throughout the world, the International Epidemiological Association commissioned a series of eight reviews that are being published in the International Journal of Epidemiology, starting in February 2011. Each review addresses one region of the world, and starts by describing the burden of disease and the current status of epidemiology, covering human resources, training, academic and research i…
CARRS Surveillance study
This surveillance model will generate data on prevalence and trends; help study the complex life-course patterns of CMDs, and provide a platform for developing and testing interventions and tools for prevention and control of CMDs in South-Asia. It will also help understanding the challenges and opportunities in establishing a surveillance system across countries
Decision support system (DSS) for prevention of cardiovascular disease (CVD) among hypertensive (HTN) patients in Andhra Pradesh, India’ – a cluster randomised community intervention trial
CTRI/2012/03/002476, Clinical Trial Registry - India
Stress and diabetes in socioeconomic context
Chronic Diseases and Poverty—Linkages and Way Ahead for the Developing World
Fruit and Vegetable Purchasing Patterns and Preferences in South Delhi
This study examines associations between consumer characteristics, beliefs, and preferences and fruit and vegetable (FV) purchasing and intake in South Delhi, India. Home interviews were conducted with 245 households, using a structured questionnaire to assess FV consumption and purchasing frequency, spending, place of purchase, mode of travel, knowledge and attitudes toward organics, and beliefs about barriers to FV consumption. In-depth intervi…
Global, regional, and national levels of neonatal, infant, and under-5 mortality during 1990–2013
BACKGROUND: Remarkable financial and political efforts have been focused on the reduction of child mortality during the past few decades. Timely measurements of levels and trends in under-5 mortality are important to assess progress towards the Millennium Development Goal 4 (MDG 4) target of reduction of child mortality by two thirds from 1990 to 2015, and to identify models of success. METHODS: We generated updated estimates of child mortality i…
Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013
A cluster-randomized controlled trial to evaluate the effects of a simplified cardiovascular management program in Tibet, China and Haryana, India
The trial was registered in the clinicaltrials.gov database on 30 December, 2011 and the registration number is NCT01503814
Is vulnerability to cardiometabolic disease in Indians mediated by abdominal adiposity or higher body adiposity
No strong evidence supports that DXA measures or abdominal measures of adiposity are better at predicting the prevalence of cardiometabolic risk factors in comparison to BMI
Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks in 188 countries, 1990–2013
Global, regional, and national disability-adjusted life years (Dalys) for 306 diseases and injuries and healthy life expectancy (Hale) for 188 countries, 1990–2013
Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013
A cross-sectional study of the prevalence and correlates of tobacco Use in Chennai, Delhi, and Karachi
High prevalence of tobacco use in the South Asian region, particularly among men, highlights the urgency to address this serious public health problem. Our analyses suggest targeted prevention and cessation interventions focused on lower socioeconomic groups may be particularly important
Dietary patterns in India and their association with obesity and central obesity
Objective Obesity is a growing problem in India, the dietary determinants of which have been studied using an ‘individual food/nutrient’ approach. Examining dietary patterns may provide more coherent findings, but few studies in developing countries have adopted this approach. The present study aimed to identify dietary patterns in an Indian population and assess their relationship with anthropometric risk factors. Design FFQ data from the cross-…
Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015
BACKGROUND: Improving survival and extending the longevity of life for all populations requires timely, robust evidence on local mortality levels and trends. The Global Burden of Disease 2015 Study (GBD 2015) provides a comprehensive assessment of all-cause and cause-specific mortality for 249 causes in 195 countries and territories from 1980 to 2015. These results informed an in-depth investigation of observed and expected mortality patterns bas…
Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990–2015
BACKGROUND: Non-fatal outcomes of disease and injury increasingly detract from the ability of the world's population to live in full health, a trend largely attributable to an epidemiological transition in many countries from causes affecting children, to non-communicable diseases (NCDs) more common in adults. For the Global Burden of Diseases, Injuries, and Risk Factors Study 2015 (GBD 2015), we estimated the incidence, prevalence, and years liv…
Medicine (70 works) · Environmental health (55 works) · Demography (29 works) · Population (28 works) · Internal Medicine (19 works) · Global Public Health Policies and Epidemiology (16 works) · Geography (15 works) · Nursing (15 works) · Pathology (15 works) · Disease (14 works)