Valentina Dorea Lima
Dados Biográficos
| ID | 1201408 |
|---|---|
| NOME | Valentina Dorea Lima |
| PRENOMES | Valentina Dorea |
| SOBRENOME | Lima |
| ASSINATURA | LIMA V D |
| AFILIAÇÕES | University of British Columbia |
| ORCID | 0000-0003-4943-091X |
| VERIFICADO | Sim |
| TOTAL DE OBRAS | 34 |
| TOTAL DE CITAÇÕES | 11 |
| TOTAL COMO AUTOR | 34 |
| TOTAL COMO EDITOR | 0 |
| PRIMEIRO ANO DE PUBLICAÇÃO | 2005 |
| ANO MAIS RECENTE DE PUBLICAÇÃO | 2025 |
| ÍNDICE H | 2 |
Identifying Syndemic Factors and Their Effect on HIV Sexual Risk Behavior Among Gay, Bisexual and Other Men Who Have Sex with Men in Vancouver, Montreal and Toronto
We set out to identify syndemic factors associated with HIV sexual risk behavior among HIV-negative gay, bisexual and other men who have sex with men (GBM), and examine associations between syndemic factors and HIV sexual risk behaviors using models of co-occurring epidemics. We used baseline data from 1571 sexually active GBM from the Engage Cohort study, recruited using respondent-driven sampling in Montreal, Toronto, and Vancouver. We explored…
Dynamics of overdose and non-overdose mortality among people living with HIV amidst the illicit drug toxicity crisis in British Columbia
We sought to characterize overdose and non-overdose mortality among PLWH amidst the illicit drug toxicity crisis in British Columbia, Canada. A population-based analysis of PLWH (age ≥19) in British Columbia accessing healthcare from April 1996 to March 2017 was conducted using data from the Seek and Treat for Optimal Prevention of HIV/AIDS (STOP HIV/AIDS) cohort linkage. Underlying causes of deaths were stratified into overdose and non-overdose …
Impact of Substance Use and Mood/Anxiety Disorders on the HIV Continuum of Care in British Columbia, Canada, from 2001 to 2019
The impact of the Covid-19 pandemic on HIV treatment gap lengths and viremia among people living with HIV British Columbia, Canada, during the Covid-19 pandemic
The SARS-CoV-2 (COVID-19) pandemic has impacted the care of people living with HIV (PLWH). This study aims to characterize the impact of the pandemic on the length of HIV treatment gap lengths and viral loads among people living with HIV (PLWH) in British Columbia (BC), Canada, with a focus on Downtown Eastside (DTES), which is one of the most impoverished neighbourhoods in Canada. We analyzed data from the HIV/AIDS Drug Treatment Program from Ja…
Infecções Nosocomiais Por Pseudomonas Aeruginosa
Introdução: Infecções hospitalares provocadas pela bactéria Pseudomonas aeruginosa (PA) são causa de óbito a nível mundial. Suas propriedades favorecem a persistência em ambiente hospitalar, em decorrência, principalmente, dos mecanismos de resistência . Os locais hospitalares com maior incidência de PA são torneiras, chuveiros, equipamentos médicos para procedimentos do trato respiratório, endoscópios e bolsas coletoras de urina. Os fatores de r…
Disability-adjusted life years associated with chronic comorbidities among people living with and without HIV
Life span of people living with HIV (PLWH) has increased dramatically with the advent of modern antiretroviral therapy. As a result, comorbidities have emerged as a significant concern in this population. To describe the burden of chronic comorbidities among PLWH and HIV-negative individuals in British Columbia (BC), Canada, we estimated disability-adjusted life years (DALYs) related to these comorbidities. Based on a population-based cohort in B…
Household food insecurity, sense of community belonging, and access to a regular medical doctor as mediators in the relationship between mood and/or anxiety disorders and self-rated general health in …
Correlates of social isolation among people living with HIV in British Columbia, Canada
Our study aims to define and identify correlates of social isolation among people living with HIV (PLHIV). The Longitudinal Investigation into Supportive and Ancillary health services (LISA) study provided a cross-sectional analytic sample of 996 PLHIV in British Columbia, Canada (sampled between 2007 and 2010). Individuals marginalized by socio-structural inequities were oversampled; sampling bias was addressed through inverse probability of par…
Overdose mortality is reducing the gains in life expectancy of antiretroviral-treated people living with HIV in British Columbia, Canada
Help-Seeking to Cope With Experiences of Violence Among Women Living With HIV in Canada
Using baseline data from a community-collaborative cohort of women living with HIV in Canada, we assessed the prevalence and correlates of help-seeking among 1,057 women who reported experiencing violence in adulthood (≥16 years). After violence, 447 (42%) sought help, while 610 (58%) did not. Frequently accessed supports included health care providers ( n = 313, 70%), family/friends ( n = 244, 55%), and non-HIV community organizations ( n = 235,…
Disparities in multimorbidity and mortality among people living with and without HIV across British Columbia’s health regions
Social Isolation and Mortality Among People Living with HIV in British Columbia, Canada
The syndemic effect of HIV/HCV co-infection and mental health disorders on acute care hospitalization rate among people living with HIV/Aids
Assessing the relationship between physician availability and viral load suppression in British Columbia
Key Messages Individuals residing in areas where there are substantially fewer physicians available to provide HIV treatment have a higher chance of not achieving viral suppression. Individuals residing in rural areas have poorer health outcomes when compared to those residing in urban areas. Discrepancies in HIV treatment outcomes exist despite the fact that HIV treatment costs are borne directly by government
Is there a rural/urban gap in the quality of HIV care for treatment-naïve HIV-positive individuals initiating antiretroviral therapy in British Columbia
Rurally located people living with HIV (PLWH) face unique challenges associated with remoteness that may negatively affect their HIV care outcomes. The Programmatic Compliance Score (PCS) has been used previously as a quality of care metric, and is predictive of mortality for treatment-naïve individuals initiating combination antiretroviral therapy (cART). This study looked at whether the rurality of PLWH impacted their PCS. PCS was calculated fo…
Envisioning Women-Centered HIV Care
Expansion of Haart Coverage Is Associated with Sustained Decreases in HIV/Aids Morbidity, Mortality and HIV Transmission
BACKGROUND: There has been renewed call for the global expansion of highly active antiretroviral therapy (HAART) under the framework of HIV treatment as prevention (TasP). However, population-level sustainability of this strategy has not been characterized. METHODS: We used population-level longitudinal data from province-wide registries including plasma viral load, CD4 count, drug resistance, HAART use, HIV diagnoses, AIDS incidence, and HIV-rel…
The effect of history of injection drug use and alcoholism on HIV disease progression
The effectiveness of highly active antiretroviral therapy (HAART) in preventing disease progression can be negatively influenced by the high prevalence of substance use among patients. Here, we quantify the effect of history of injection drug use and alcoholism on virologic and immunologic response to HAART. Clinical and survey data, collected at the start of HAART and at the interview date, were based on the study Longitudinal Investigations int…
Antiretroviral Drug Costs and Prescription Patterns in British Columbia, Canada
INTRODUCTION: Treatment options and therapeutic guidelines have evolved substantially since highly active antiretroviral treatment (HAART) became the standard of HIV care in 1996. We conducted the present population-based analysis to characterize the determinants of direct costs of HAART over time in British Columbia, Canada. METHODS: We considered individuals ever receiving HAART in British Columbia from 1996 to 2011. Linear mixed-effects regres…
Tuberculosis in HIV-infected persons in British Columbia during the Haart era
Hepatitis C virus treatment for prevention among people who inject drugs
UNLABELLED: Substantial reductions in hepatitis C virus (HCV) prevalence among people who inject drugs (PWID) cannot be achieved by harm reduction interventions such as needle exchange and opiate substitution therapy (OST) alone. Current HCV treatment is arduous and uptake is low, but new highly effective and tolerable interferon-free direct-acting antiviral (DAA) treatments could facilitate increased uptake. We projected the potential impact of …
Validating a Shortened Depression Scale (10 Item CES-D) among HIV-Positive People in British Columbia, Canada
OBJECTIVE: To establish the reliability and validity of a shortened (10-item) depression scale used among HIV-positive patients enrolled in the Drug Treatment Program in British Columbia, Canada. METHODS: The 10-item CES-D (Center for Epidemiologic Studies Depression Scale) was examined among 563 participants who initiated antiretroviral therapy (ART) between August 1, 1996 and June 30, 2002. Internal consistency of the scale was measured by Cron…
Suboptimal use of HIV drug resistance testing in a universal health-care setting
HIV drug resistance testing is recommended as routine part of clinical practice in HIV/AIDS treatment and care. Our objective is to assess the determinants of accessing HIV drug resistance testing and examine the factors associated with resistance testing prior to or after starting highly active antiretroviral therapy (HAART) in a setting where access to HIV care is free and universal. The Longitudinal Investigation into Supportive and Ancillary …
“The way I see it”
With significant reductions in AIDS-related morbidity and mortality, HIV is increasingly viewed as a chronic condition. However, people on antiretroviral therapy (ART) are experiencing new challenges such as metabolic and morphological body changes, which may affect self-perceived body image. The concept of body image is complex and encompasses an individual's perception of their existential self, physical self and social interpretation of their …
Association of highly active antiretroviral therapy coverage, population viral load, and yearly new HIV diagnoses in British Columbia, Canada
Quantifying the effect of health status on health care utilization using a preference-based health measure
Migration adversely affects antiretroviral adherence in a population-based cohort of HIV/Aids patients
The impact of the Covid-19 pandemic on HIV treatment gap lengths and viremia among people living with HIV British Columbia, Canada, during the Covid-19 pandemic
The SARS-CoV-2 (COVID-19) pandemic has impacted the care of people living with HIV (PLWH). This study aims to characterize the impact of the pandemic on the length of HIV treatment gap lengths and viral loads among people living with HIV (PLWH) in British Columbia (BC), Canada, with a focus on Downtown Eastside (DTES), which is one of the most impoverished neighbourhoods in Canada. We analyzed data from the HIV/AIDS Drug Treatment Program from Ja…
Household food insecurity, sense of community belonging, and access to a regular medical doctor as mediators in the relationship between mood and/or anxiety disorders and self-rated general health in …
Regional and Temporal Changes in HIV-related Mortality in British Columbia, 1987–2006
Quantifying the effect of health status on health care utilization using a preference-based health measure
The effect of adherence on the association between depressive symptoms and mortality among HIV-infected individuals first initiating Haart
OBJECTIVE: To determine the impact of depressive symptoms on mortality among HIV/AIDS patients first initiating HAART and the potential role of patient adherence as a confounder and effect modifier in this association. METHODS: The study comprised HIV-positive individuals who were first prescribed HAART between August 1996 and June 2002. Depressive symptoms were assessed using the Center for Epidemiologic Studies Depression Scale. Cox proportiona…
The Association Between Food Insecurity and Mortality Among HIV-Infected Individuals on Haart
BACKGROUND: Food insecurity is increasingly recognized as a barrier to optimal treatment outcomes, but there is little data on this issue. We assessed associations between food insecurity and mortality among HIV-infected antiretroviral therapy-treated individuals in Vancouver, British Columbia, and whether body max index (BMI) modified associations. METHODS: Individuals were recruited from the British Columbia HIV/AIDS drug treatment program in 1…
The WHOMEN’s Scale (Women’s Haart Optimism Monitoring and EvaluatioN Scale v.1) and the Association with Fertility Intentions and Sexual Behaviours Among HIV-Positive Women in Uganda
Association Between HIV-1 RNA Level and CD4 Cell Count Among Untreated HIV-Infected Individuals
Objectives. We examined the significance of plasma HIV-1 RNA levels (or viral load alone) in predicting CD4 cell decline in untreated HIV-infected individuals. Methods. Data were obtained from the British Columbia Centre for Excellence in HIV/AIDS. Participants included all residents who ever had a viral load determination in the province and who had never taken antiretroviral drugs (N = 890). We analyzed a total of 2074 viral load measurements a…
Migration adversely affects antiretroviral adherence in a population-based cohort of HIV/Aids patients
Association of highly active antiretroviral therapy coverage, population viral load, and yearly new HIV diagnoses in British Columbia, Canada
Factors behind HIV testing practices among Canadian Aboriginal peoples living off-reserve
The objective of this study was to examine factors associated with HIV testing among Aboriginal peoples in Canada who live off-reserve. Data were drawn for individuals aged 15-44 from the Aboriginal Peoples Survey (2001), which represents a weighed sample of 520,493 Aboriginal men and women living off-reserve. Bivariable analysis and logistic regression were used to identify factors associated with individuals who had received an HIV test within …
Regional and Temporal Changes in HIV-related Mortality in British Columbia, 1987–2006
Regional and Temporal Trends in Migration among People Living with HIV/Aids in British Columbia, 1993-2005
Suboptimal use of HIV drug resistance testing in a universal health-care setting
HIV drug resistance testing is recommended as routine part of clinical practice in HIV/AIDS treatment and care. Our objective is to assess the determinants of accessing HIV drug resistance testing and examine the factors associated with resistance testing prior to or after starting highly active antiretroviral therapy (HAART) in a setting where access to HIV care is free and universal. The Longitudinal Investigation into Supportive and Ancillary …
“The way I see it”
With significant reductions in AIDS-related morbidity and mortality, HIV is increasingly viewed as a chronic condition. However, people on antiretroviral therapy (ART) are experiencing new challenges such as metabolic and morphological body changes, which may affect self-perceived body image. The concept of body image is complex and encompasses an individual's perception of their existential self, physical self and social interpretation of their …
Validating a Shortened Depression Scale (10 Item CES-D) among HIV-Positive People in British Columbia, Canada
OBJECTIVE: To establish the reliability and validity of a shortened (10-item) depression scale used among HIV-positive patients enrolled in the Drug Treatment Program in British Columbia, Canada. METHODS: The 10-item CES-D (Center for Epidemiologic Studies Depression Scale) was examined among 563 participants who initiated antiretroviral therapy (ART) between August 1, 1996 and June 30, 2002. Internal consistency of the scale was measured by Cron…
Hepatitis C virus treatment for prevention among people who inject drugs
UNLABELLED: Substantial reductions in hepatitis C virus (HCV) prevalence among people who inject drugs (PWID) cannot be achieved by harm reduction interventions such as needle exchange and opiate substitution therapy (OST) alone. Current HCV treatment is arduous and uptake is low, but new highly effective and tolerable interferon-free direct-acting antiviral (DAA) treatments could facilitate increased uptake. We projected the potential impact of …
Expansion of Haart Coverage Is Associated with Sustained Decreases in HIV/Aids Morbidity, Mortality and HIV Transmission
BACKGROUND: There has been renewed call for the global expansion of highly active antiretroviral therapy (HAART) under the framework of HIV treatment as prevention (TasP). However, population-level sustainability of this strategy has not been characterized. METHODS: We used population-level longitudinal data from province-wide registries including plasma viral load, CD4 count, drug resistance, HAART use, HIV diagnoses, AIDS incidence, and HIV-rel…
The effect of history of injection drug use and alcoholism on HIV disease progression
The effectiveness of highly active antiretroviral therapy (HAART) in preventing disease progression can be negatively influenced by the high prevalence of substance use among patients. Here, we quantify the effect of history of injection drug use and alcoholism on virologic and immunologic response to HAART. Clinical and survey data, collected at the start of HAART and at the interview date, were based on the study Longitudinal Investigations int…
Antiretroviral Drug Costs and Prescription Patterns in British Columbia, Canada
INTRODUCTION: Treatment options and therapeutic guidelines have evolved substantially since highly active antiretroviral treatment (HAART) became the standard of HIV care in 1996. We conducted the present population-based analysis to characterize the determinants of direct costs of HAART over time in British Columbia, Canada. METHODS: We considered individuals ever receiving HAART in British Columbia from 1996 to 2011. Linear mixed-effects regres…
Tuberculosis in HIV-infected persons in British Columbia during the Haart era
Is there a rural/urban gap in the quality of HIV care for treatment-naïve HIV-positive individuals initiating antiretroviral therapy in British Columbia
Rurally located people living with HIV (PLWH) face unique challenges associated with remoteness that may negatively affect their HIV care outcomes. The Programmatic Compliance Score (PCS) has been used previously as a quality of care metric, and is predictive of mortality for treatment-naïve individuals initiating combination antiretroviral therapy (cART). This study looked at whether the rurality of PLWH impacted their PCS. PCS was calculated fo…
Envisioning Women-Centered HIV Care
Assessing the relationship between physician availability and viral load suppression in British Columbia
Key Messages Individuals residing in areas where there are substantially fewer physicians available to provide HIV treatment have a higher chance of not achieving viral suppression. Individuals residing in rural areas have poorer health outcomes when compared to those residing in urban areas. Discrepancies in HIV treatment outcomes exist despite the fact that HIV treatment costs are borne directly by government
The syndemic effect of HIV/HCV co-infection and mental health disorders on acute care hospitalization rate among people living with HIV/Aids
Social Isolation and Mortality Among People Living with HIV in British Columbia, Canada
Correlates of social isolation among people living with HIV in British Columbia, Canada
Our study aims to define and identify correlates of social isolation among people living with HIV (PLHIV). The Longitudinal Investigation into Supportive and Ancillary health services (LISA) study provided a cross-sectional analytic sample of 996 PLHIV in British Columbia, Canada (sampled between 2007 and 2010). Individuals marginalized by socio-structural inequities were oversampled; sampling bias was addressed through inverse probability of par…
Overdose mortality is reducing the gains in life expectancy of antiretroviral-treated people living with HIV in British Columbia, Canada
Medicine (34 obras) · HIV/AIDS Research and Interventions (28 obras) · Demography (19 obras) · HIV, Drug Use, Sexual Risk (17 obras) · Environmental health (16 obras) · Gerontology (14 obras) · Internal Medicine (14 obras) · Population (13 obras) · HIV-related health complications and treatments (11 obras) · Human immunodeficiency virus (HIV (11 obras)