Bertrand Lebouché
Datos Biográficos
| ID | 1265834 |
|---|---|
| NOMBRE | Bertrand Lebouché |
| NOMBRES | Bertrand |
| APELLIDO | Lebouché |
| FIRMA | LEBOUCHÉ B |
| AFILIACIONES | McGill University Health Centre |
| ORCID | 0000-0002-1273-9393 |
| VERIFICADO | Sí |
| TOTAL DE OBRAS | 28 |
| TOTAL DE CITAS | 1 |
| TOTAL COMO AUTOR | 28 |
| TOTAL COMO EDITOR | 0 |
| PRIMER AÑO DE PUBLICACIÓN | 2013 |
| AÑO MÁS RECIENTE DE PUBLICACIÓN | 2026 |
| ÍNDICE H | 1 |
A cost-effectiveness analysis of a multidisciplinary model of care on hepatitis C care among people released from provincial prison in Quebec, Canada
Our multidisciplinary model of care increased the proportion of HCV RNA+ people released from prison who subsequently achieved SVR, at an additional cost of C$25,653 per additional patient. This is only C$5,653 more than the estimated cost of direct-acting antivirals, providing an economic rationale for broader implementation
Studied factors and metrics of patient portal use among people with HIV
For people living with HIV (PLHIV), patient portals could facilitate access to personal health records while promoting self-management and retention in care. Given the apparent heterogeneity in the studied factors influencing portal use among PLHIV and the metrics used in research, we conducted a rapid scoping review to inventory them. Two databases were searched (Medline and Embase on the Ovid platform) from conception until 15 September 2023. T…
A pre-post study of the impact of a multidisciplinary model of care on linkage to hepatitis C care following release from prison
A multidisciplinary model of care increased linkage to HCV care among untreated individuals released from prison. Future interventions should support similar models, leveraging social support networks to maximize continuity of care
Relationship Breakup Impact on Mental Health and Safer Sex Among Men Who Have Sex with Men in the United Kingdom
This study investigated the impact of breakup recency and relationship status on mental health (anxiety, depression, suicidal ideation, possible alcohol dependence, sexual unhappiness, worry about drug use) and safer sex (sexual assertiveness and non-steady condomless partners) among men who have sex with men (MSM) in the United Kingdom (UK). We analyzed data from 11,763 UK-based MSM in the European MSM Internet Survey. ANOVAs were run to explore…
Interventions, Barriers, and Facilitators to Address the Sexual Problems of Gay, Bisexual and Other Men Who Have Sex with Men Living with HIV
Perceived patient navigator services and characteristics to address barriers to linkage to hepatitis C care among people released from provincial prison in Quebec, Canada
Interventions that seek to improve linkage to HCV care for people following release from prison should address many levels (individual, interpersonal, and policy) of the SEM. While people experience several competing priorities post-release, having an empathetic and consistent patient navigator, regardless of their lived experiences of HCV and/or incarceration, may improve linkage to HCV care post-release
Earlier First Anal Sex Predicts Engagement in Chemsex Among Men Who Have Sex with Men in the United Kingdom
Chemsex, a form of sexualized drug use, is prevalent among men who have sex with men (MSM) in the United Kingdom (UK), contributing to public health concerns like increased HIV transmission and overdose risk. This study explored the link between early first anal sex and chemsex engagement among MSM, a connection that has been underexplored in the UK. Analyzing data from 10,702 UK-based MSM from the European MSM Internet Survey (EMIS-2017), we use…
Disclosure of HIV-serodiscordant relationships and association with viral suppression
BACKGROUND: Little is known about the effects of disclosure of HIV-serodiscordant relationships on clinical outcomes. We aimed to evaluate the effect of relationship disclosure on HIV viral suppression, and hypothesized that disclosure by HIV-positive and HIV-negative partners would be associated with viral suppression in the HIV-positive partner. METHODS: We conducted a Canadian national online and telephone-administered survey of HIV-positive a…
Public health interventions, priority populations, and the impact of Covid-19 disruptions on hepatitis C elimination among people who have injected drugs in Montreal (Canada)
HCV treatment scale-up among all PWID will be required to eliminate HCV in high-incidence and prevalence settings. Achieving elimination by 2030 will entail concerted efforts to restore and enhance pre-pandemic levels of HCV prevention and care
Interventions to Improve Uptake of Direct-Acting Antivirals for Hepatitis C Virus in Priority Populations
Characterization of people living with HIV in a Montreal-based tertiary care center with Covid-19 during the first wave of the pandemic
[347, 726] and six had detectable plasma HIV viral loads. Median duration of HIV was 17 years [7, 22] and 30 individuals had been prescribed antiretroviral therapy. Five persons were asymptomatic. Of symptomatic persons, 21 (12%), 1 (4%) and 3 (12%) individuals had mild, moderate and severe disease, respectively. Three individuals died with COVID-19. In one case, the cause of death was due to COVID-19, whereas in the other two cases, the individu…
Social capital and HIV-serodiscordance
As people living with HIV are living longer lives, they have a correspondingly greater opportunity to enjoy long-term romantic and sexual partnerships, including with persons who do not live with HIV ("serodiscordant" relationships). In these dyads, asymmetries may emerge in access to social resources between partners. In this paper we examined how serodiscordant couples access informal (interpersonal, such as family and friends) and formal (prac…
A national recruitment strategy for HIV-serodiscordant partners living in Canada for the Positive Plus One study
Our findings provide important new information on and support the use of a multi-pronged approach to recruit HIV-positive and HIV-negative individuals involved in HIV-serodiscordant relationships in Canada. More creative strategies are needed to help index partners recruit their partner in relationships with lower satisfaction and shorter duration and further minimize the risk of "happy couple" bias
Implementation of Lost & Found, An Intervention to Reengage Patients Out of HIV Care
Being out of HIV care (OOC) is associated with increased morbidity and mortality. We assessed implementation of Lost & Found, a clinic-based intervention to reengage OOC patients. OOC patients were identified using a nurse-validated, real-time OOC list within the electronic medical records (EMR) system. Nurses called OOC patients. Implementation occurred at the McGill University Health Centre from April 2018 to 2019. Results from questionnaires t…
Dual pharmaceutical citizenship
Patient and provider perceived barriers and facilitators to direct acting antiviral hepatitis C treatment among priority populations in high income countries
BACKGROUND: Direct acting antivirals (DAAs) have increased cure rates for hepatitis C virus (HCV) infection; however, there are several obstacles to the uptake of DAAs in populations where substance use contributes to HCV risk. This synthesis aimed to identify the patient and provider perceived barriers and facilitators to DAA treatment initiation in key patient subgroups-people who inject drugs (PWID), men who have sex with men (MSM), and Indige…
The involvement of people living with HIV in the development of HIV-specific or inclusive health instruments
Given recent emphasis on patient engagement in the choice and development of health measures to ensure their relevance, we examined the involvement of people living with HIV (PLHIV) in the creation of health measurement instruments that are HIV-specific or inclusive. A mixed studies review was conducted describing: 1) the sampling, recruitment and characteristics of involved PLHIV; 2) the methods and extent of their involvement; and 3) study auth…
Evaluation of a project to engage patients in the development of a patient‐reported measure for HIV care (the I‐Score Study)
BACKGROUND: Patient engagement (PE), patients' meaningful involvement in research through partnerships and sensitivity to their expertise, is receiving attention. However, PE initiatives are poorly reported and little is known about patients' perspective on PE. OBJECTIVE: To document and evaluate the first phase (22 months) of a PE Project for the I-Score Study which is developing a patient-reported measure of HIV treatment adherence barriers, we…
Delayed linkage to HIV care among asylum seekers in Quebec, Canada
While the majority of newly diagnosed asylum seekers were late presenters, only 45% were linked to care within 30 days. Once linked, care and viral suppression were rapid. Delays in screening and linkage to care present increased risk for onward transmission, and in the context of 21% baseline resistance, consideration of point-of-care testing and immediate referral at IME screening should be made
Decision-making about motherhood among women living with HIV in Canada
Little research in Canada has examined the perspectives of women living with HIV on decision-making across the stages of motherhood. In 2004-2005, semi-structured interviews were conducted with 42 African, Caucasian and Haitian HIV-positive women recruited in Montreal. All were or wished to be biological mothers. Transcripts underwent thematic analysis organised by three culturally informed models of motherhood described by the participants, whic…
Patient profiles as organizing HIV clinicians’ ART adherence management
The effectiveness of antiretroviral therapy (ART) depends on optimal clinical management and patient adherence. Little is known about patient characteristics that clinicians consider in the management of ART adherence. Exploring this issue, five focus groups were conducted with 31 HIV-clinicians from across France. A qualitative typological analysis suggests that clinician management of patient adherence is based on characteristics that coalesce …
Barriers to antiretroviral therapy adherence in developed countries
Suboptimal adherence to antiretroviral therapy (ART) remains common. Patient-centered tools are needed to comprehensively assess adherence barriers in HIV clinical practice. Thus, we conducted a research synthesis to produce a conceptual framework for a new patient-reported outcome measure (PRO) for use in routine HIV care in Canada and France. A PRO's conceptual framework graphically represents the concepts to be measured and the potential relat…
Interventions to increase testing, linkage to care and treatment of hepatitis C virus (HCV) infection among people in prisons
Developing a patient-reported outcome measure for HIV care on perceived barriers to antiretroviral adherence
Explaining the appeal for immigrant men who have sex with men of a community-based rapid HIV-testing site in Montreal (Actuel sur Rue)
Immigrant men who have sex with men (MSM) are vulnerable to HIV. In the last decade, several rapid HIV-testing facilities targeting MSM have been established around the world and seem popular among immigrants. This study analyzes factors contributing to immigrant MSM's use of Actuel sur Rue (AsR), a community-based rapid HIV-testing site in Montreal's gay village, where 31% of clients are immigrants. From October 2013 to January 2014, AsR staff c…
Minimal interference
Given international interest in "treatment as prevention" (TasP) and the pertinence of optimizing antiretroviral treatment (ART) regimens for TasP, 19 French HIV experts were interviewed on their criteria for ART if used specifically for prevention with HIV-positive persons. Through content analysis of the interview material, nine criteria were identified. The most endorsed criteria, collectively, suggest a choice of treatment based on "minimal i…
Family quality of life in families affected by HIV
The HIV infection of a family member can impact family quality of life (FQoL). The objectives of this study are to (1) describe patterns of FQoL among mothers living with HIV (MLHIV) and (2) identify key factors associated with FQoL in families affected by HIV. Recruitment took place in HIV-specialized clinics and community organizations. A 100 MLHIV and 67 of their children participated in this study. Mothers were on average 40.8 years old and r…
Explaining the appeal for immigrant men who have sex with men of a community-based rapid HIV-testing site in Montreal (Actuel sur Rue)
Immigrant men who have sex with men (MSM) are vulnerable to HIV. In the last decade, several rapid HIV-testing facilities targeting MSM have been established around the world and seem popular among immigrants. This study analyzes factors contributing to immigrant MSM's use of Actuel sur Rue (AsR), a community-based rapid HIV-testing site in Montreal's gay village, where 31% of clients are immigrants. From October 2013 to January 2014, AsR staff c…
Barriers to health-care and psychological distress among mothers living with HIV in Quebec (Canada)
Health-care providers play a major role in providing good quality care and in preventing psychological distress among mothers living with HIV (MLHIV). The objectives of this study are to explore the impact of health-care services and satisfaction with care providers on psychological distress in MLHIV. One hundred MLHIV were recruited from community and clinical settings in the province of Quebec (Canada). Prevalence estimation of clinical psychol…
Developing a patient-reported outcome measure for HIV care on perceived barriers to antiretroviral adherence
Patient profiles as organizing HIV clinicians’ ART adherence management
The effectiveness of antiretroviral therapy (ART) depends on optimal clinical management and patient adherence. Little is known about patient characteristics that clinicians consider in the management of ART adherence. Exploring this issue, five focus groups were conducted with 31 HIV-clinicians from across France. A qualitative typological analysis suggests that clinician management of patient adherence is based on characteristics that coalesce …
Barriers to antiretroviral therapy adherence in developed countries
Suboptimal adherence to antiretroviral therapy (ART) remains common. Patient-centered tools are needed to comprehensively assess adherence barriers in HIV clinical practice. Thus, we conducted a research synthesis to produce a conceptual framework for a new patient-reported outcome measure (PRO) for use in routine HIV care in Canada and France. A PRO's conceptual framework graphically represents the concepts to be measured and the potential relat…
Interventions to increase testing, linkage to care and treatment of hepatitis C virus (HCV) infection among people in prisons
Evaluation of a project to engage patients in the development of a patient‐reported measure for HIV care (the I‐Score Study)
BACKGROUND: Patient engagement (PE), patients' meaningful involvement in research through partnerships and sensitivity to their expertise, is receiving attention. However, PE initiatives are poorly reported and little is known about patients' perspective on PE. OBJECTIVE: To document and evaluate the first phase (22 months) of a PE Project for the I-Score Study which is developing a patient-reported measure of HIV treatment adherence barriers, we…
Delayed linkage to HIV care among asylum seekers in Quebec, Canada
While the majority of newly diagnosed asylum seekers were late presenters, only 45% were linked to care within 30 days. Once linked, care and viral suppression were rapid. Delays in screening and linkage to care present increased risk for onward transmission, and in the context of 21% baseline resistance, consideration of point-of-care testing and immediate referral at IME screening should be made
Decision-making about motherhood among women living with HIV in Canada
Little research in Canada has examined the perspectives of women living with HIV on decision-making across the stages of motherhood. In 2004-2005, semi-structured interviews were conducted with 42 African, Caucasian and Haitian HIV-positive women recruited in Montreal. All were or wished to be biological mothers. Transcripts underwent thematic analysis organised by three culturally informed models of motherhood described by the participants, whic…
The involvement of people living with HIV in the development of HIV-specific or inclusive health instruments
Given recent emphasis on patient engagement in the choice and development of health measures to ensure their relevance, we examined the involvement of people living with HIV (PLHIV) in the creation of health measurement instruments that are HIV-specific or inclusive. A mixed studies review was conducted describing: 1) the sampling, recruitment and characteristics of involved PLHIV; 2) the methods and extent of their involvement; and 3) study auth…
Patient and provider perceived barriers and facilitators to direct acting antiviral hepatitis C treatment among priority populations in high income countries
BACKGROUND: Direct acting antivirals (DAAs) have increased cure rates for hepatitis C virus (HCV) infection; however, there are several obstacles to the uptake of DAAs in populations where substance use contributes to HCV risk. This synthesis aimed to identify the patient and provider perceived barriers and facilitators to DAA treatment initiation in key patient subgroups-people who inject drugs (PWID), men who have sex with men (MSM), and Indige…
Interventions to Improve Uptake of Direct-Acting Antivirals for Hepatitis C Virus in Priority Populations
Characterization of people living with HIV in a Montreal-based tertiary care center with Covid-19 during the first wave of the pandemic
[347, 726] and six had detectable plasma HIV viral loads. Median duration of HIV was 17 years [7, 22] and 30 individuals had been prescribed antiretroviral therapy. Five persons were asymptomatic. Of symptomatic persons, 21 (12%), 1 (4%) and 3 (12%) individuals had mild, moderate and severe disease, respectively. Three individuals died with COVID-19. In one case, the cause of death was due to COVID-19, whereas in the other two cases, the individu…
Social capital and HIV-serodiscordance
As people living with HIV are living longer lives, they have a correspondingly greater opportunity to enjoy long-term romantic and sexual partnerships, including with persons who do not live with HIV ("serodiscordant" relationships). In these dyads, asymmetries may emerge in access to social resources between partners. In this paper we examined how serodiscordant couples access informal (interpersonal, such as family and friends) and formal (prac…
A national recruitment strategy for HIV-serodiscordant partners living in Canada for the Positive Plus One study
Our findings provide important new information on and support the use of a multi-pronged approach to recruit HIV-positive and HIV-negative individuals involved in HIV-serodiscordant relationships in Canada. More creative strategies are needed to help index partners recruit their partner in relationships with lower satisfaction and shorter duration and further minimize the risk of "happy couple" bias
Implementation of Lost & Found, An Intervention to Reengage Patients Out of HIV Care
Being out of HIV care (OOC) is associated with increased morbidity and mortality. We assessed implementation of Lost & Found, a clinic-based intervention to reengage OOC patients. OOC patients were identified using a nurse-validated, real-time OOC list within the electronic medical records (EMR) system. Nurses called OOC patients. Implementation occurred at the McGill University Health Centre from April 2018 to 2019. Results from questionnaires t…
Dual pharmaceutical citizenship
Disclosure of HIV-serodiscordant relationships and association with viral suppression
BACKGROUND: Little is known about the effects of disclosure of HIV-serodiscordant relationships on clinical outcomes. We aimed to evaluate the effect of relationship disclosure on HIV viral suppression, and hypothesized that disclosure by HIV-positive and HIV-negative partners would be associated with viral suppression in the HIV-positive partner. METHODS: We conducted a Canadian national online and telephone-administered survey of HIV-positive a…
Public health interventions, priority populations, and the impact of Covid-19 disruptions on hepatitis C elimination among people who have injected drugs in Montreal (Canada)
HCV treatment scale-up among all PWID will be required to eliminate HCV in high-incidence and prevalence settings. Achieving elimination by 2030 will entail concerted efforts to restore and enhance pre-pandemic levels of HCV prevention and care
Interventions, Barriers, and Facilitators to Address the Sexual Problems of Gay, Bisexual and Other Men Who Have Sex with Men Living with HIV
Perceived patient navigator services and characteristics to address barriers to linkage to hepatitis C care among people released from provincial prison in Quebec, Canada
Interventions that seek to improve linkage to HCV care for people following release from prison should address many levels (individual, interpersonal, and policy) of the SEM. While people experience several competing priorities post-release, having an empathetic and consistent patient navigator, regardless of their lived experiences of HCV and/or incarceration, may improve linkage to HCV care post-release
Earlier First Anal Sex Predicts Engagement in Chemsex Among Men Who Have Sex with Men in the United Kingdom
Chemsex, a form of sexualized drug use, is prevalent among men who have sex with men (MSM) in the United Kingdom (UK), contributing to public health concerns like increased HIV transmission and overdose risk. This study explored the link between early first anal sex and chemsex engagement among MSM, a connection that has been underexplored in the UK. Analyzing data from 10,702 UK-based MSM from the European MSM Internet Survey (EMIS-2017), we use…
Studied factors and metrics of patient portal use among people with HIV
For people living with HIV (PLHIV), patient portals could facilitate access to personal health records while promoting self-management and retention in care. Given the apparent heterogeneity in the studied factors influencing portal use among PLHIV and the metrics used in research, we conducted a rapid scoping review to inventory them. Two databases were searched (Medline and Embase on the Ovid platform) from conception until 15 September 2023. T…
Medicine (25 obras) · HIV/AIDS Research and Interventions (22 obras) · Psychology (19 obras) · Family medicine (18 obras) · HIV, Drug Use, Sexual Risk (13 obras) · Sociology (11 obras) · Human immunodeficiency virus (HIV (10 obras) · Demography (8 obras) · Nursing (8 obras) · Qualitative research (8 obras)