David S Krantz
Biographic Data
| ID | 1358486 |
|---|---|
| NAME | David S Krantz |
| GIVEN NAMES | David S |
| FAMILY NAME | Krantz |
| SIGNATURE | KRANTZ D S |
| AFFILIATIONS | Uniformed Services University of the Health Sciences |
| ORCID | 0000-0002-1671-1355 |
| VERIFIED | Yes |
| TOTAL WORKS | 43 |
| TOTAL CITATIONS | 97 |
| WORKS AS AUTHOR | 43 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 1973 |
| LATEST PUBLICATION YEAR | 2014 |
| H-INDEX | 4 |
Current Perspective on Mental Stress–Induced Myocardial Ischemia
Psychological and Physiological Predictors of Angina During Exercise-Induced Ischemia in Patients With Coronary Artery Disease
OBJECTIVE: This study compares sensory-biological, cognitive-emotional, and cognitive-interpretational factors in predicting angina on an exercise treadmill test (ETT). METHODS: A total of 163 patients with ETT-induced ischemia and coronary artery disease in the National Heart, Lung, and Blood Institute Psychophysiological Investigations of Myocardial Ischemia study were given an ETT, during which 79 patients reported angina. We assessed the foll…
Combining Psychosocial Data to Improve Prediction of Cardiovascular Disease Risk Factors and Events
Background There is overlap among psychosocial predictors of cardiovascular disease (CVD). The usefulness of combining psychosocial variables as risk markers for CVD needs investigation. Methods Participants were 493 women in the NHLBI WISE study. Multivariate combination of Beck Depression Inventory (BDI), State-Trait Anxiety Inventory (STAI), Social Network Index (SNI), and Cook-Medley hostility subscales was evaluated, and principal components…
Self-Rated Versus Objective Health Indicators as Predictors of Major Cardiovascular Events
OBJECTIVE: To determine the association between self-rated health and major cardiovascular events in a sample of women with suspected myocardial ischemia. Previous studies showed that self-rated health is a predictor of objective health outcomes, such as mortality. METHOD: At baseline, 900 women rated their health on a 5-point scale ranging from poor to excellent as part of a protocol that included quantitative coronary angiography, cardiovascula…
Comorbid Depression and Anxiety Symptoms as Predictors of Cardiovascular Events
OBJECTIVE: To study the independent and interactive effects of depression and anxiety symptoms as predictors of cardiovascular disease (CVD) events in a sample of women with suspected myocardial ischemia. Symptoms of depression and anxiety overlap strongly and are independent predictors of CVD events. Although these symptoms commonly co-occur in medical patients, little is known about combined effects of depression and anxiety on CVD risk. METHOD…
Association Between Symptoms of Depression and Anxiety With Heart Rate Variability in Patients With Implantable Cardioverter Defibrillators
OBJECTIVE: This study investigated whether depression and anxiety symptoms are associated with measures of autonomic nervous system dysfunction in patients with implantable cardioverter defibrillators who are at high risk of cardiac rhythm disturbances. Depression and anxiety are associated with autonomic nervous system dysfunction, which may promote the risk of malignant cardiac arrhythmias. METHODS: Patients with an implantable cardioverter def…
Depression, the Metabolic Syndrome and Cardiovascular Risk
BACKGROUND: The relationship between depression and the metabolic syndrome is unclear, and whether metabolic syndrome explains the association between depression and cardiovascular disease (CVD) risk is unknown. METHODS: We studied 652 women who received coronary angiography as part of the Women's Ischemia Syndrome Evaluation (WISE) study and completed the Beck Depression Inventory (BDI). Women who had both elevated depressive symptoms (BDI > or …
Social Networks and Incident Stroke Among Women With Suspected Myocardial Ischemia
OBJECTIVE: To describe the prospective relationship between social networks and nonfatal stroke events in a sample of women with suspected myocardial ischemia. Social networks are an independent predictor of all-cause and cardiovascular mortality, but their relationship with stroke events in at-risk populations is largely unknown. METHOD: A total of 629 women (mean age = 59.6 +/- 11.6 years) were evaluated at baseline for cardiovascular disease r…
Mental Stress Hemodynamic Responses and Myocardial Ischemia
Objective: To assess if mental stress hemodynamic responses are impaired and related to mental stress (MS) ischemia in patients with left ventricular (LV) dysfunction. Background: Impaired LV function is an important coronary artery disease (CAD) risk factor and hemodynamic characteristics play an important role in clinical outcomes. Patients with severe LV dysfunction (SLVD) are frequently excluded from prior studies and the effects of LV dysfun…
Hostility Scores Are Associated With Increased Risk of Cardiovascular Events in Women Undergoing Coronary Angiography
OBJECTIVE: To evaluate hostility-related personality traits assessed by the Cook Medley Hostility Inventory and to relate these to the occurrence of adverse cardiac events in women with suspected myocardial ischemia. METHODS: The cohort included 506 women with suspected coronary artery disease from the National Heart, Lung, and Blood Institute-sponsored Women's Ischemia Syndrome Evaluation (WISE) study. We examined individual components of the Co…
Social Network and Coronary Artery Calcification in Asymptomatic Individuals
BACKGROUND: Psychosocial factors are associated with the development of coronary artery disease. However, studies examining psychosocial factors as risk indicators for coronary artery calcification (CAC) have been inconclusive. METHODS: Seven hundred eighty-three participants (mean age 57.4 +/- 9.3 years, 47% female) underwent CAC imaging using electron beam tomography. Psychosocial measures included social network (number of people in the househ…
Effects of Psychological and Social Factors on Organic Disease
An extensive research literature in the behavioral sciences and medicine suggests that psychological and social factors may play a direct role in organic coronary artery disease (CAD) pathology. However, many in the medical and scientific community regard this evidence with skepticism. This chapter critically examines research on the impact of psychological and psychosocial factors on the development and outcome of coronary heart disease, with pa…
Psychological Correlates of Mental Stress-induced Ischemia in the Laboratory
Participants consisted of 184 patients (160 males, 24 females) with positive angiograms or prior myocardial infarctions who displayed at least 1 mm of ST segment depression on a standardized treadmill test. Mean scores on the Reward Dependence subscale of the Tridimensional Personality Questionnaire were higher in patients displaying ischemia during mental stress. Patients who reported higher levels of irritability/anger in response to the Speech…
Physical Activity and the Diurnal Pattern of Myocardial Ischemia in Patients With Coronary Artery Disease
Quigley, J. F.; Suchday, S.; Gottdiener, J. S.; Bairey-Merz, C.; Krantz, D. S.; Kop, W. J.; Patterson, S. M. Author Information
Mental Stress Testing in Patients With Implantable Cardioverter Defibrillators
s of Papers for 1999 Annual Meeting: Symposium: Psychosocial Factors in Malignant Cardiac Arrhythmias and Their Treatment with Implanted Defibrillators
The Psychophysiological Investigations of Myocardial Ischemia (Pimi) Study
OBJECTIVE: This study evaluated physiological, neuroendocrine, and psychological status and functioning of patients with coronary artery disease in order to clarify their role in the expression of symptoms during myocardial ischemia (MI), and to establish repeatability of responses to mental stress. Design and methods of the study are presented. METHODS: One hundred ninety-six coronary artery disease patients were examined during physical and men…
Reproducibility of Mental Stress-Induced Myocardial Ischemia in the Psychophysiological Investigations of Myocardial Ischemia (Pimi)
OBJECTIVE: Many patients with coronary artery disease (CAD) develop myocardial ischemia in response to mental stress. This has been documented both in the natural environment and in the laboratory. However, the reproducibility of laboratory mental stress-induced ischemia has not been investigated. METHOD: Sixty patients with documented CAD and a positive exercise stress test discontinued cardiac medications and underwent two standardized mental s…
Prothrombotic Effects of Environmental Stress
Mental stress can affect a range of variables relevant to hemostasis and thrombosis. However, research has not clarified whether these effects occur as part of a generalized sympathoadrenal response or whether stress-induced increases in catecholamines and blood pressure have selective and independent effects on hematologic variables. This study assessed the effects of mental and cold pressor stress on platelet activation, hematocrit, and total p…
Hostility and myocardial ischemia in coronary artery disease patients
Two studies assess relationships of hostility to extent and severity of exercise-induced cardiac ischemia and daily life ischemia in patients with coronary artery disease (CAD). CAD patients (N = 80) who underwent exercise tomographic thallium testing to assess myocardial perfusion completed the Cook-Medley Hostility Inventory (Ho). A Composite Hostility (Chost) score obtained from the Ho scale was also used. Statistically controlling for the eff…
Effects of acute mental stress on serum lipids
The present study assessed the acute effects of mental stress (mental arithmetic) on serum cholesterol, triglycerides, high-density lipoprotein-cholesterol (HDL-C), and low-density lipoprotein-cholesterol (LDL-C), and the extent to which stress-induced changes are attributable to decreases in plasma volume. Total cholesterol, triglycerides, HDL-C, and LDL-C were assessed in 18 healthy men (35 +/- 7 years) during a resting baseline (30 minutes), c…
Cardiovascular reactivity and mental stress-induced myocardial ischemia in patients with coronary artery disease
This report evaluates the relationships of hemodynamic reactivity and determinants of myocardial oxygen demand to myocardial ischemia during mental stress in coronary artery disease patients. Thirty-nine patients and 12 controls were studied by radionuclide ventriculography during three mental tasks (arithmetic, Stroop task, and simulated public speaking). Patients were subdivided into three groups based on the severity of ischemic wall motion re…
Environmental Influences on Mental Health
Comparative effects of two beta-blockers on cardiovascular reactivity and type A behavior in hypertensives
This study compared the effects of beta-blockers differing in degree of central nervous system penetration on Type A behavior and cardiovascular reactivity to mental stress. Forty-six male hypertensives were assigned randomly to receive either highly lipophilic and nonselective propranolol, hydrophilic and cardioselective atenolol, the diuretic hydrochlorothiazide, or placebo. Subjects were administered parallel forms of the Structured Interview …
Environmental stress, reactivity and ischaemic heart disease
This article provides an overview of work in two areas of biobehavioural research: the effects of environmental stress and the role of psychophysiologic reactivity in the development of ischaemic heart disease. Attention is given first to evidence that low socio‐economic status, low social support, and occupational settings characterized by high demands and low levels of control over the job are associated with increased coronary risk. Also discu…
Effects of beta-adrenergic stimulation and blockade on cardiovascular reactivity, affect, and type A behavior
The present study examined the acute effects of drugs that stimulate or block sympathetic nervous system activity on components of Type A behavior, affect, and cardiovascular responses to mental stressors. Either propranolol (a beta-adrenergic blocker), isoproterenol (a beta-agonist), or placebo was infused intravenously at different times in 12 healthy males. In two sessions, placebo (saline) was administered first, followed by a structured inte…
Helplessness, stress level, and the coronary-prone behavior pattern
Assessment of preferences for self-treatment and information in health care
It has been assumed that it is beneficial for patients to become active and informed participants in health care. Previous research, however, suggests that individuals differ in their receptiveness to information and self-care in treatment stiuations. This article reports the development and validation of the Krantz Health Opinion Survey, a measure of preferences for different treatment approaches. This measure yields a total score and two relati…
Information, choice, and reactions to stress
Two experiments examined the effects of various operations of personal control on reactions to stress. The first study incorporated two features into the blood drawing procedure at a blood bank: providing donors with accurate information and allowing donors to choose the arm to be used. Measurement of nurses' actions to prevent donors from fainting and self-reports of discomfort revealed that the combination of choice and information was somewhat…
Unique and common variance in Structured Interview and Jenkins Activity Survey measures of Type A behavior pattern
The aim of the present study was to identify factors that account for similarities and discrepancies in classification of Type A and B behavior by the Structured Interview (SI) and by the Jenkins Activity Survey (JAS). Two diverse samples were administered the SI and the JAS. SI questions were coded for content of response and psychomotor behavior during the interview. Frequency of specific Type A speech characteristics and clinical judgments wer…
Environmental stress, reactivity and ischaemic heart disease
This article provides an overview of work in two areas of biobehavioural research: the effects of environmental stress and the role of psychophysiologic reactivity in the development of ischaemic heart disease. Attention is given first to evidence that low socio‐economic status, low social support, and occupational settings characterized by high demands and low levels of control over the job are associated with increased coronary risk. Also discu…
Aircraft noise and children
Assessed the impact of noise on attentional strategies, learned helplessness, performance on cognitive tasks, and blood pressure. Third and 4th graders were tested on the same measures twice, with a 1-yr interval between sessions. Longitudinal data were used to determine whether Ss adapted to aircraft noise over the 1-yr period and to assess the effectiveness of noise abatement interventions introduced in a number of noise-impacted classrooms. Ad…
Perceived control of aversive stimulation and the reduction of stress responses 1
Helplessness, stress level, and the coronary-prone behavior pattern
Resemblances of Twins and Their Parents in Pattern A Behavior
A twin study was conducted to determine the relative contribution of genetic and environmental factors to the development of Pattern A behavior. Thirty-five sets of college-aged MZ twins and 21 sets of DZ twins completed the lenkins Activity Survey for Health Prediction. This self-administering questionnaire yields scales measuring Pattern A behavior and its related traits of Speed and Impatience, Job Involvement, and Hard-driving Competitiveness…
Locus of control and the effects of success and failure in young and community-residing aged women1
A study was conducted to examine reactions to success and failure in young and elderly subjects. Young and aged women, previously classified as internals or externals according to scores on a version of Rotter's (1966) Locus of Control Scale, were asked to work on cognitive problems while listening to bursts of noise. Two experimental conditions were created. One group (perceived success) was led to believe they were successfully avoiding bursts …
Psychological Correlates of Progression of Atherosclerosis in Men
Patients who underwent repetitive repetitive coronary angiograms at an average interval of 17 months completed the Jenkins Activity Survey (n = 66) and were given the Rosenman diagnostic interview to measure Type A behavior (n = 45). Significant progression of coronary artery disease was judged to be an increase in occlusion of 25% or more, or progression to total occlusion in any vessel. At subsequent study, 30% of the patients showed evidence o…
A Naturalistic Study of Social Influences on Meal Size among Moderately Obese and Nonobese Subjects
The present study examined the amount of food chosen by moderately obese and nonobese customers in a university cafeteria as a function of whether they were about to eat alone or were explicitly accompanied by others during lunch. It was hypothesized that many overweight individuals are self-conscious about eating due to perceived social pressures, and that obese people would therefore choose less food (i.e., suppress intake) when eating with oth…
Information, choice, and reactions to stress
Two experiments examined the effects of various operations of personal control on reactions to stress. The first study incorporated two features into the blood drawing procedure at a blood bank: providing donors with accurate information and allowing donors to choose the arm to be used. Measurement of nurses' actions to prevent donors from fainting and self-reports of discomfort revealed that the combination of choice and information was somewhat…
Physiological, motivational, and cognitive effects of aircraft noise on children
Studied the effects of aircraft noise on 3rd- and 4th-grade students as evidence for the effects of community noise on behavior and as an example of a study that examines the generality of laboratory effects in a naturalistic setting. The impact of noise on attentional strategies, feelings of personal control, and physiological processes related to health was measured. Results are consistent with laboratory work on physiological response to noise…
Assessment of preferences for self-treatment and information in health care
It has been assumed that it is beneficial for patients to become active and informed participants in health care. Previous research, however, suggests that individuals differ in their receptiveness to information and self-care in treatment stiuations. This article reports the development and validation of the Krantz Health Opinion Survey, a measure of preferences for different treatment approaches. This measure yields a total score and two relati…
Aircraft noise and children
Assessed the impact of noise on attentional strategies, learned helplessness, performance on cognitive tasks, and blood pressure. Third and 4th graders were tested on the same measures twice, with a 1-yr interval between sessions. Longitudinal data were used to determine whether Ss adapted to aircraft noise over the 1-yr period and to assess the effectiveness of noise abatement interventions introduced in a number of noise-impacted classrooms. Ad…
Type A Behavior and Coronary Artery Bypass Surgery
Previous research has suggested that Type A, compared to Type B patients undergoing coronary artery bypass surgery evidence greater intraoperative increases over hospital admission systolic blood pressure, even though patients are under general anesthesia. The present study sought to examine whether such blood pressure increases are accounted for by elevations occurring entirely during surgery (with conscious mediation minimized), or by increases…
Perspectives on the interface between psychology and public health
Perspectives on the interface between psychology and public health
Unique and common variance in Structured Interview and Jenkins Activity Survey measures of Type A behavior pattern
The aim of the present study was to identify factors that account for similarities and discrepancies in classification of Type A and B behavior by the Structured Interview (SI) and by the Jenkins Activity Survey (JAS). Two diverse samples were administered the SI and the JAS. SI questions were coded for content of response and psychomotor behavior during the interview. Frequency of specific Type A speech characteristics and clinical judgments wer…
Behavioral Correlates of Angiography
Acute psychophysiologic reactivity and risk of cardiovascular disease
Acute psychophysiologic reactivity and risk of cardiovascular disease
Effects of beta-adrenergic stimulation and blockade on cardiovascular reactivity, affect, and type A behavior
The present study examined the acute effects of drugs that stimulate or block sympathetic nervous system activity on components of Type A behavior, affect, and cardiovascular responses to mental stressors. Either propranolol (a beta-adrenergic blocker), isoproterenol (a beta-agonist), or placebo was infused intravenously at different times in 12 healthy males. In two sessions, placebo (saline) was administered first, followed by a structured inte…
Some Cautions for Research on Personality and Health
This article comments on three conceptualizations of the relationship between personality and disease as they relate to the papers in this issue Despite the sophistication and promise of recent research in this area, conceptual and methodological difficulties present in earlier psychosomatic research have persisted In this area, robust and convincing associations between traits and disease remain largely elusive, and stable, valid measures of psy…
Comparative effects of two beta-blockers on cardiovascular reactivity and type A behavior in hypertensives
This study compared the effects of beta-blockers differing in degree of central nervous system penetration on Type A behavior and cardiovascular reactivity to mental stress. Forty-six male hypertensives were assigned randomly to receive either highly lipophilic and nonselective propranolol, hydrophilic and cardioselective atenolol, the diuretic hydrochlorothiazide, or placebo. Subjects were administered parallel forms of the Structured Interview …
Environmental stress, reactivity and ischaemic heart disease
This article provides an overview of work in two areas of biobehavioural research: the effects of environmental stress and the role of psychophysiologic reactivity in the development of ischaemic heart disease. Attention is given first to evidence that low socio‐economic status, low social support, and occupational settings characterized by high demands and low levels of control over the job are associated with increased coronary risk. Also discu…
Environmental Influences on Mental Health
Cardiovascular reactivity and mental stress-induced myocardial ischemia in patients with coronary artery disease
This report evaluates the relationships of hemodynamic reactivity and determinants of myocardial oxygen demand to myocardial ischemia during mental stress in coronary artery disease patients. Thirty-nine patients and 12 controls were studied by radionuclide ventriculography during three mental tasks (arithmetic, Stroop task, and simulated public speaking). Patients were subdivided into three groups based on the severity of ischemic wall motion re…
Hostility and myocardial ischemia in coronary artery disease patients
Two studies assess relationships of hostility to extent and severity of exercise-induced cardiac ischemia and daily life ischemia in patients with coronary artery disease (CAD). CAD patients (N = 80) who underwent exercise tomographic thallium testing to assess myocardial perfusion completed the Cook-Medley Hostility Inventory (Ho). A Composite Hostility (Chost) score obtained from the Ho scale was also used. Statistically controlling for the eff…
Effects of acute mental stress on serum lipids
The present study assessed the acute effects of mental stress (mental arithmetic) on serum cholesterol, triglycerides, high-density lipoprotein-cholesterol (HDL-C), and low-density lipoprotein-cholesterol (LDL-C), and the extent to which stress-induced changes are attributable to decreases in plasma volume. Total cholesterol, triglycerides, HDL-C, and LDL-C were assessed in 18 healthy men (35 +/- 7 years) during a resting baseline (30 minutes), c…
Medicine (36 works) · Internal Medicine (27 works) · Internal Medicine (26 works) · Psychology (26 works) · Cardiac Health and Mental Health (20 works) · Cardiology (17 works) · Psychiatry (15 works) · Coronary artery disease (12 works) · Social Psychology (10 works) · Clinical Psychology (9 works)