Eduardo Tarazona‐santo
Biographic Data
| ID | 150045 |
|---|---|
| NAME | Eduardo Tarazona‐santo |
| GIVEN NAMES | Eduardo |
| FAMILY NAME | Tarazona‐santo |
| SIGNATURE | SANTO E T |
| AFFILIATIONS | Universidade Federal de Minas Gerais |
| ORCID | 0000-0003-3508-3160 |
| VERIFIED | Yes |
| TOTAL WORKS | 12 |
| TOTAL CITATIONS | 18 |
| AUTHOR COUNT | 12 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2000 |
| LATEST PUBLICATION YEAR | 2018 |
| H-INDEX | 2 |
Biogeographical ancestry is associated with socioenvironmental conditions and infections in a Latin American urban population
Racial inequalities are observed for different diseases and are mainly caused by differences in socioeconomic status between ethnoracial groups. Genetic factors have also been implicated, and recently, several studies have investigated the association between biogeographical ancestry (BGA) and complex diseases. However, the role of BGA as a proxy for non-genetic health determinants has been little investigated. Similarly, studies comparing the as…
A tale of agriculturalists and hunter‐gatherers: Exploring the thrifty genotype hypothesis in native South Americans
OBJECTIVES: To determine genetic differences between agriculturalist and hunter-gatherer southern Native American populations for selected metabolism-related markers and to test whether Neel's thrifty genotype hypothesis (TGH) could explain the genetic patterns observed in these populations. MATERIALS AND METHODS: 375 Native South American individuals from 17 populations were genotyped using six markers (APOE rs429358 and rs7412; APOA2 rs5082; CD…
Brief communication: 5‐HTTLPR genetic diversity and mode of subsistence in Native Americans
The relationship between the “individualism‐collectivism” and the serotonin transporter functional polymorphism (5‐HTTLPR), suggested in the previous reports, was tested in Native South Amerindian populations. A total of 170 individuals from 21 populations were genotyped for the 5‐HTTLPR alleles. For comparative purposes, these populations were classified as individualistic (recent history of hunter–gathering) or collectivistic (agriculturalists)…
The population genetics of quechuas, the largest native south american group: Autosomal sequences, SNPs, and microsatellites evidence high level of diversity
Elucidating the pattern of genetic diversity for non‐European populations is necessary to make the benefits of human genetics research available to individuals from these groups. In the era of large human genomic initiatives, Native American populations have been neglected, in particular, the Quechua, the largest South Amerindian group settled along the Andes. We characterized the genetic diversity of a Quechua population in a global setting, usi…
Autosome STRs in native South America-Testing models of association with geography and language
Information on one Ecuadorian and three Peruvian Amerindian populations for 11 autosomal short tandem repeat (STR) loci is presented and incorporated in analyses that includes 26 other Native groups spread all over South America. Although in comparison with other studies we used a reduced number of markers, the number of populations included in our analyses is currently unmatched by any genome-wide dataset. The genetic polymorphisms indicate a cl…
Genetic Differentiation in South Amerindians Is Related to Environmental and Cultural Diversity: Evidence from the Y Chromosome
Body size, composition, and blood pressure of high‐altitude Quechua from the Peruvian Central Andes (Huancavelica, 3,680 m)
Although much information is available about the effects of high altitude on physiological characteristics, less is know about its effect on body composition. In the present study, anthropometric and body composition variables were investigated in a sample of 77 adult Quechua males from the Peruvian Central Andes (Huancavelica, 3,680 m). The subjects are shorter in relation to body weight than other ethnic groups, whereas body proportions are mac…
Hematological and pulmonary responses to high altitude in Quechuas: A multivariate approach
This study investigates the relationships among hematological variables, pulmonary function, and age in a sample of high-altitude natives. The following anthropometric and physiological variables were examined in 77 adult Quechua males from the Peruvian Central Andes (Huancavelica, 3,680 m): height, weight, sitting height, chest diameters, chest and abdominal circumferences, forced vital capacity (FVC), forced expiratory volume at 1 sec (FEV1), p…
Hematological and pulmonary responses to high altitude in Quechuas: A multivariate approach
Lung volume, chest size, and hematological variation in low-, medium-, and high-altitude Central Asian populations
To evaluate adaptive responses to high-altitude environment, we examined three groups of healthy adult males from Central Asia: 94 high-altitude (HA) Kirghiz subjects (3,200 m above sea level); 114 middle-altitude (MA) Kazakh subjects (2,100 m), and 90 low-altitude (LA) Kirghiz subjects (900 m). Data on chest size (chest perimeter and chest diameter), lung volume (forced expiratory volume (FEV) and forced expiratory volume in 1 sec (FEV1)), and h…
Lung volume, chest size, and hematological variation in low‐, medium‐, and high‐altitude Central Asian populations
Genetic structure of Quechua-speakers of the Central Andes and geographic patterns of gene frequencies in South Amerindian populations
A sample of 141 Quechua-speaking individuals of the population of Tayacaja, in the Peruvian Central Andes, was typed for the following 16 genetic systems: ABO, Rh, MNSs, P, Duffy, AcP1, EsD, GLOI, PGM1, AK, 6-PGD, Hp, Gc, Pi, C3, and Bf. The genetic structure of the population was analyzed in relation to the allele frequencies available for other South Amerindian populations, using a combination of multivariate and multivariable techniques. Spati…
Autosome STRs in native South America-Testing models of association with geography and language
Information on one Ecuadorian and three Peruvian Amerindian populations for 11 autosomal short tandem repeat (STR) loci is presented and incorporated in analyses that includes 26 other Native groups spread all over South America. Although in comparison with other studies we used a reduced number of markers, the number of populations included in our analyses is currently unmatched by any genome-wide dataset. The genetic polymorphisms indicate a cl…
The population genetics of quechuas, the largest native south american group: Autosomal sequences, SNPs, and microsatellites evidence high level of diversity
Elucidating the pattern of genetic diversity for non‐European populations is necessary to make the benefits of human genetics research available to individuals from these groups. In the era of large human genomic initiatives, Native American populations have been neglected, in particular, the Quechua, the largest South Amerindian group settled along the Andes. We characterized the genetic diversity of a Quechua population in a global setting, usi…
A tale of agriculturalists and hunter‐gatherers: Exploring the thrifty genotype hypothesis in native South Americans
OBJECTIVES: To determine genetic differences between agriculturalist and hunter-gatherer southern Native American populations for selected metabolism-related markers and to test whether Neel's thrifty genotype hypothesis (TGH) could explain the genetic patterns observed in these populations. MATERIALS AND METHODS: 375 Native South American individuals from 17 populations were genotyped using six markers (APOE rs429358 and rs7412; APOA2 rs5082; CD…
Brief communication: 5‐HTTLPR genetic diversity and mode of subsistence in Native Americans
The relationship between the “individualism‐collectivism” and the serotonin transporter functional polymorphism (5‐HTTLPR), suggested in the previous reports, was tested in Native South Amerindian populations. A total of 170 individuals from 21 populations were genotyped for the 5‐HTTLPR alleles. For comparative purposes, these populations were classified as individualistic (recent history of hunter–gathering) or collectivistic (agriculturalists)…
Hematological and pulmonary responses to high altitude in Quechuas: A multivariate approach
This study investigates the relationships among hematological variables, pulmonary function, and age in a sample of high-altitude natives. The following anthropometric and physiological variables were examined in 77 adult Quechua males from the Peruvian Central Andes (Huancavelica, 3,680 m): height, weight, sitting height, chest diameters, chest and abdominal circumferences, forced vital capacity (FVC), forced expiratory volume at 1 sec (FEV1), p…
Hematological and pulmonary responses to high altitude in Quechuas: A multivariate approach
Lung volume, chest size, and hematological variation in low-, medium-, and high-altitude Central Asian populations
To evaluate adaptive responses to high-altitude environment, we examined three groups of healthy adult males from Central Asia: 94 high-altitude (HA) Kirghiz subjects (3,200 m above sea level); 114 middle-altitude (MA) Kazakh subjects (2,100 m), and 90 low-altitude (LA) Kirghiz subjects (900 m). Data on chest size (chest perimeter and chest diameter), lung volume (forced expiratory volume (FEV) and forced expiratory volume in 1 sec (FEV1)), and h…
Lung volume, chest size, and hematological variation in low‐, medium‐, and high‐altitude Central Asian populations
Genetic structure of Quechua-speakers of the Central Andes and geographic patterns of gene frequencies in South Amerindian populations
A sample of 141 Quechua-speaking individuals of the population of Tayacaja, in the Peruvian Central Andes, was typed for the following 16 genetic systems: ABO, Rh, MNSs, P, Duffy, AcP1, EsD, GLOI, PGM1, AK, 6-PGD, Hp, Gc, Pi, C3, and Bf. The genetic structure of the population was analyzed in relation to the allele frequencies available for other South Amerindian populations, using a combination of multivariate and multivariable techniques. Spati…
Genetic Differentiation in South Amerindians Is Related to Environmental and Cultural Diversity: Evidence from the Y Chromosome
Body size, composition, and blood pressure of high‐altitude Quechua from the Peruvian Central Andes (Huancavelica, 3,680 m)
Although much information is available about the effects of high altitude on physiological characteristics, less is know about its effect on body composition. In the present study, anthropometric and body composition variables were investigated in a sample of 77 adult Quechua males from the Peruvian Central Andes (Huancavelica, 3,680 m). The subjects are shorter in relation to body weight than other ethnic groups, whereas body proportions are mac…
Autosome STRs in native South America-Testing models of association with geography and language
Information on one Ecuadorian and three Peruvian Amerindian populations for 11 autosomal short tandem repeat (STR) loci is presented and incorporated in analyses that includes 26 other Native groups spread all over South America. Although in comparison with other studies we used a reduced number of markers, the number of populations included in our analyses is currently unmatched by any genome-wide dataset. The genetic polymorphisms indicate a cl…
The population genetics of quechuas, the largest native south american group: Autosomal sequences, SNPs, and microsatellites evidence high level of diversity
Elucidating the pattern of genetic diversity for non‐European populations is necessary to make the benefits of human genetics research available to individuals from these groups. In the era of large human genomic initiatives, Native American populations have been neglected, in particular, the Quechua, the largest South Amerindian group settled along the Andes. We characterized the genetic diversity of a Quechua population in a global setting, usi…
Brief communication: 5‐HTTLPR genetic diversity and mode of subsistence in Native Americans
The relationship between the “individualism‐collectivism” and the serotonin transporter functional polymorphism (5‐HTTLPR), suggested in the previous reports, was tested in Native South Amerindian populations. A total of 170 individuals from 21 populations were genotyped for the 5‐HTTLPR alleles. For comparative purposes, these populations were classified as individualistic (recent history of hunter–gathering) or collectivistic (agriculturalists)…
A tale of agriculturalists and hunter‐gatherers: Exploring the thrifty genotype hypothesis in native South Americans
OBJECTIVES: To determine genetic differences between agriculturalist and hunter-gatherer southern Native American populations for selected metabolism-related markers and to test whether Neel's thrifty genotype hypothesis (TGH) could explain the genetic patterns observed in these populations. MATERIALS AND METHODS: 375 Native South American individuals from 17 populations were genotyped using six markers (APOE rs429358 and rs7412; APOA2 rs5082; CD…
Biogeographical ancestry is associated with socioenvironmental conditions and infections in a Latin American urban population
Racial inequalities are observed for different diseases and are mainly caused by differences in socioeconomic status between ethnoracial groups. Genetic factors have also been implicated, and recently, several studies have investigated the association between biogeographical ancestry (BGA) and complex diseases. However, the role of BGA as a proxy for non-genetic health determinants has been little investigated. Similarly, studies comparing the as…
Biology (7 works) · Demography (7 works) · Medicine (7 works) · Population (7 works) · Allele (5 works) · Gene (5 works) · Genetics (5 works) · High Altitude and Hypoxia (5 works) · Altitude (triangle) (4 works) · Evolutionary biology (4 works)