René S Kahn
Datos Biográficos
| ID | 151559 |
|---|---|
| NOMBRE | René S Kahn |
| NOMBRES | René S |
| APELLIDO | Kahn |
| FIRMA | KAHN R S |
| AFILIACIONES | University Medical Center Utrecht |
| ORCID | 0000-0001-5909-8004 |
| VERIFICADO | Sí |
| TOTAL DE OBRAS | 13 |
| TOTAL DE CITAS | 3 |
| TOTAL COMO AUTOR | 13 |
| TOTAL COMO EDITOR | 0 |
| PRIMER AÑO DE PUBLICACIÓN | 2010 |
| AÑO MÁS RECIENTE DE PUBLICACIÓN | 2023 |
| ÍNDICE H | 1 |
Revealing the impact of psychiatric comorbidities on treatment outcome in early psychosis using counterfactual model explanation
These results highlight the importance of identifying and including relevant comorbidities in prediction models, providing valuable insights for improving the treatment and prognosis of patients with psychotic disorders. Furthermore, they open avenues for further research into the efficacy of treating these comorbidities to enhance overall patient outcomes
Mapping genomic loci implicates genes and synaptic biology in schizophrenia
Accelerated Global and Local Brain Aging Differentiate Cognitively Impaired From Cognitively Spared Patients With Schizophrenia
Accelerated aging in schizophrenia can be detected at the early disease stages and appears more closely associated with cognitive dysfunction rather than clinical symptoms. Future studies replicating our findings in multi-site cohorts with larger numbers of participants are warranted
The Association Between Emotion Recognition, Affective Empathy, and Structural Connectivity in Schizophrenia Patients
In patients with poor emotion recognition, the negative association between anterior thalamic radiation AD and affective empathy was stronger than in patients with normal emotion recognition capacity. Possibly, axonal damage in fronto-thalamic structural connections, as part of a larger frontotemporal network, underlies the association between poor emotion recognition and higher levels of affective empathy in schizophrenia patients
L'alsacien dans la sphère économique
L'affaire semble entendue : les langues régionales et leurs locuteurs comme tous les acteurs et toutes les ressources mobilisables sont placés sous l'emprise de la rationalité, des pratiques et des finalités économiques et ils en souffrent. D'autant que le modèle dominant de la concurrence généralisée et de la mondialisation s'impose sans partage et sans autre langage que celui du calcul économique. Dans ce contexte, les usages économiques de l'a…
Extensions of Multiple-Group Item Response Theory Alignment
Large-scale studies spanning diverse project sites, populations, languages, and measurements are increasingly important to relate psychological to biological variables. National and international consortia already are collecting and executing mega-analyses on aggregated data from individuals, with different measures on each person. In this research, we show that Asparouhov and Muthén's alignment method can be adapted to align data from disparate …
Shared vulnerability for connectome alterations across psychiatric and neurological brain disorders
Intelligence and Brain Efficiency
Intelligence is a measure of general cognitive functioning capturing a wide variety of different cognitive functions. It has been hypothesized that the brain works to minimize the resources allocated toward higher cognitive functioning. Thus, for the intelligent brain, it may be that not simply more is better, but rather, more efficient is better. Energy metabolism supports both inhibitory and excitatory neurotransmission processes. Indeed, in gl…
Detecting Neuroimaging Biomarkers for Psychiatric Disorders
In a recent review, it was suggested that much larger cohorts are needed to prove the diagnostic value of neuroimaging biomarkers in psychiatry. While within a sample, an increase of diagnostic accuracy of schizophrenia (SZ) with number of subjects (N) has been shown, the relationship between N and accuracy is completely different between studies. Using data from a recent meta-analysis of machine learning (ML) in imaging SZ, we found that while l…
Effects of a culturally sensitive assessment on symptom profiles in native Dutch and Moroccan patients with a first psychosis referral
Previous studies have reported a higher incidence of psychosis in Moroccan immigrants in the Netherlands than among native-born residents. However, this disparity was substantially attenuated when cultural differences in symptom presentation were taken into account. To better understand the impact of different diagnostic procedures on incidence rates, we examined the effects of the use of a culturally sensitive diagnostic interview, compared to a…
Structural MRI Differences between Patients with and without First Rank Symptoms
Brain volume differences between patients with and without FRS are, when present, subtle, and not consistent between three independent samples. Brain abnormalities related to FRS may be too subtle to become visible through structural brain imaging
Cannabis Use is a Better Indicator of Poor Mental Health in Women Than in Men
La dimension culturelle du développement territorial
La prise en compte des aspects culturels du développement correspond à une évolution de la réalité économique mais aussi à une évolution épistémologique en économie spatiale et régionale. Après avoir identifié les différentes acceptions de la notion de territoire dans la littérature, nous privilégions celle qui le définit comme une construction d’acteurs partageant une même culture du développement. La dimension culturelle qui est désormais parti…
Cannabis Use is a Better Indicator of Poor Mental Health in Women Than in Men
Effects of a culturally sensitive assessment on symptom profiles in native Dutch and Moroccan patients with a first psychosis referral
Previous studies have reported a higher incidence of psychosis in Moroccan immigrants in the Netherlands than among native-born residents. However, this disparity was substantially attenuated when cultural differences in symptom presentation were taken into account. To better understand the impact of different diagnostic procedures on incidence rates, we examined the effects of the use of a culturally sensitive diagnostic interview, compared to a…
La dimension culturelle du développement territorial
La prise en compte des aspects culturels du développement correspond à une évolution de la réalité économique mais aussi à une évolution épistémologique en économie spatiale et régionale. Après avoir identifié les différentes acceptions de la notion de territoire dans la littérature, nous privilégions celle qui le définit comme une construction d’acteurs partageant une même culture du développement. La dimension culturelle qui est désormais parti…
Cannabis Use is a Better Indicator of Poor Mental Health in Women Than in Men
Structural MRI Differences between Patients with and without First Rank Symptoms
Brain volume differences between patients with and without FRS are, when present, subtle, and not consistent between three independent samples. Brain abnormalities related to FRS may be too subtle to become visible through structural brain imaging
Detecting Neuroimaging Biomarkers for Psychiatric Disorders
In a recent review, it was suggested that much larger cohorts are needed to prove the diagnostic value of neuroimaging biomarkers in psychiatry. While within a sample, an increase of diagnostic accuracy of schizophrenia (SZ) with number of subjects (N) has been shown, the relationship between N and accuracy is completely different between studies. Using data from a recent meta-analysis of machine learning (ML) in imaging SZ, we found that while l…
Effects of a culturally sensitive assessment on symptom profiles in native Dutch and Moroccan patients with a first psychosis referral
Previous studies have reported a higher incidence of psychosis in Moroccan immigrants in the Netherlands than among native-born residents. However, this disparity was substantially attenuated when cultural differences in symptom presentation were taken into account. To better understand the impact of different diagnostic procedures on incidence rates, we examined the effects of the use of a culturally sensitive diagnostic interview, compared to a…
Intelligence and Brain Efficiency
Intelligence is a measure of general cognitive functioning capturing a wide variety of different cognitive functions. It has been hypothesized that the brain works to minimize the resources allocated toward higher cognitive functioning. Thus, for the intelligent brain, it may be that not simply more is better, but rather, more efficient is better. Energy metabolism supports both inhibitory and excitatory neurotransmission processes. Indeed, in gl…
Shared vulnerability for connectome alterations across psychiatric and neurological brain disorders
Extensions of Multiple-Group Item Response Theory Alignment
Large-scale studies spanning diverse project sites, populations, languages, and measurements are increasingly important to relate psychological to biological variables. National and international consortia already are collecting and executing mega-analyses on aggregated data from individuals, with different measures on each person. In this research, we show that Asparouhov and Muthén's alignment method can be adapted to align data from disparate …
Mapping genomic loci implicates genes and synaptic biology in schizophrenia
Accelerated Global and Local Brain Aging Differentiate Cognitively Impaired From Cognitively Spared Patients With Schizophrenia
Accelerated aging in schizophrenia can be detected at the early disease stages and appears more closely associated with cognitive dysfunction rather than clinical symptoms. Future studies replicating our findings in multi-site cohorts with larger numbers of participants are warranted
The Association Between Emotion Recognition, Affective Empathy, and Structural Connectivity in Schizophrenia Patients
In patients with poor emotion recognition, the negative association between anterior thalamic radiation AD and affective empathy was stronger than in patients with normal emotion recognition capacity. Possibly, axonal damage in fronto-thalamic structural connections, as part of a larger frontotemporal network, underlies the association between poor emotion recognition and higher levels of affective empathy in schizophrenia patients
L'alsacien dans la sphère économique
L'affaire semble entendue : les langues régionales et leurs locuteurs comme tous les acteurs et toutes les ressources mobilisables sont placés sous l'emprise de la rationalité, des pratiques et des finalités économiques et ils en souffrent. D'autant que le modèle dominant de la concurrence généralisée et de la mondialisation s'impose sans partage et sans autre langage que celui du calcul économique. Dans ce contexte, les usages économiques de l'a…
Revealing the impact of psychiatric comorbidities on treatment outcome in early psychosis using counterfactual model explanation
These results highlight the importance of identifying and including relevant comorbidities in prediction models, providing valuable insights for improving the treatment and prognosis of patients with psychotic disorders. Furthermore, they open avenues for further research into the efficacy of treating these comorbidities to enhance overall patient outcomes
Psychology (10 obras) · Psychiatry (9 obras) · Medicine (8 obras) · Neuroscience (5 obras) · Schizophrenia (object-oriented programming (5 obras) · Clinical Psychology (4 obras) · Functional Brain Connectivity Studies (4 obras) · Cognitive psychology (3 obras) · Mental Health Research Topics (3 obras) · Mental Health Treatment and Access (3 obras)