Bradley S Peterson
Biographic Data
| ID | 1660168 |
|---|---|
| NAME | Bradley S Peterson |
| GIVEN NAMES | Bradley S |
| FAMILY NAME | Peterson |
| SIGNATURE | PETERSON B S |
| AFFILIATIONS | Columbia University |
| ORCID | 0000-0001-5737-225X |
| VERIFIED | Yes |
| TOTAL WORKS | 15 |
| TOTAL CITATIONS | 8 |
| WORKS AS AUTHOR | 15 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 2002 |
| LATEST PUBLICATION YEAR | 2025 |
| H-INDEX | 2 |
Brain tissue microstructure in a prospective, longitudinal, population‐based cohort of preterm and term‐born young adults
BACKGROUND: Fifteen million infants annually are born prematurely, placing them at high risk for life-long adverse neurodevelopmental outcomes. Whether brain tissue abnormalities that accompany preterm birth persist into young adulthood and are associated with long-term cognitive or psychiatric outcomes is not known. METHODS: From infancy into young adulthood, we followed a population-based sample of consecutively identified preterm infants and t…
Advancing the treatment of anxiety disorders in transition‐age youth
BACKGROUND: The real-world effectiveness of exposure-based therapies for youth depends on the willingness and ability of young people to tolerate confronting their fears, which can be experienced as highly aversive and create problems with treatment engagement and acceptance. Recently, neuroscientific research on the nonconscious basis of fear has been translated into novel exposure interventions that bypass conscious processing of feared stimuli…
Association of 24‐Hour Ambulatory Blood Pressure During Pregnancy in Adolescents and Young Adults With Measures of Fetal Autonomic Nervous System Development
The autonomic nervous system regulates physiological processes, including cardiovascular functions. Changes in maternal systolic and diastolic blood pressure (SBP; DBP), as well as fetal heart rate and heart rate variability, can serve as indicators of possible risk for adverse perinatal and developmental outcomes. This study examined the association between maternal blood pressure during pregnancy and fetal autonomic nervous system heart rate in…
All we have to fear is fear itself”
438). We organize these findings within a neuroscientific framework and evaluate alternative mechanisms for unconscious exposure. The use of incommensurate outcome measures across exposure paradigms and nonreporting of relevant statistics limited meta-analyses. Despite steps taken to address publication bias, 25.6% of included studies came from a single laboratory. We propose potential clinical applications of these findings. Future research shou…
Causal effects of psychostimulants on neural connectivity
BACKGROUND: Psychostimulants are frequently used to treat attention-deficit/hyperactivity disorder (ADHD), but side effects are common leading to many patients discontinuing treatment. Identifying neural mechanisms by which psychostimulants attenuate symptoms may guide the development of more refined and tolerable therapeutics. METHODS: We conducted a 12-week, randomized, placebo-controlled trial (RCT) of a long-acting amphetamine, lisdexamfetami…
Prenatal exposure to air pollution is associated with altered brain structure, function, and metabolism in childhood
Background Prenatal exposure to air pollution disrupts cognitive, emotional, and behavioral development. The brain disturbances associated with prenatal air pollution are largely unknown. Methods In this prospective cohort study, we estimated prenatal exposures to fine particulate matter (PM 2.5 ) and polycyclic aromatic hydrocarbons (PAH), and then assessed their associations with measures of brain anatomy, tissue microstructure, neurometabolite…
Using tissue microstructure and multimodal MRI to parse the phenotypic heterogeneity and cellular basis of autism spectrum disorder
BACKGROUND: Identifying the brain bases for phenotypic heterogeneity in Autism Spectrum Disorder (ASD) will advance understanding of its pathogenesis and improve its clinical management. METHODS: We compared Diffusion Tensor Imaging (DTI) indices and connectome measures between 77 ASD and 88 Typically Developing (TD) control participants. We also assessed voxel-wise associations of DTI indices with measures of regional cerebral blood flow (rCBF) …
Prenatal exposure to polycyclic aromatic hydrocarbons modifies the effects of early life stress on attention and Thought Problems in late childhood
BACKGROUND: Risk for childhood psychopathology is complex and multifactorial, implicating direct and interacting effects of familial and environmental factors. The role of environmental neurotoxicants in psychiatric risk is of growing concern, including polycyclic aromatic hydrocarbons (PAH), common in air pollution. Prenatal PAH exposure is linked to adverse physical, behavioral, and cognitive outcomes as well as increasing psychiatric risk. It …
Profiles of infant communicative behavior
Prior studies of mother-infant interaction have generally used a variable-centered approach to associate face-to-face communication with psychosocial outcomes. Herein, we use a person-centered approach to identify clusters of infants who exhibit similar behavioral profiles during face-to-face communication with their mothers. Four infant communication channels were examined-gaze, facial affect, vocal affect, and head orientation-coded from videot…
Somatoform Pain
Somatoform pain is a highly prevalent, debilitating condition and a tremendous public health problem. Effective treatments for somatoform pain are urgently needed. The etiology of this condition is, however, still unknown. On the basis of a review of recent basic and clinical research, we propose one potential mechanism of symptom formation in somatoform pain and a developmental theory of its pathogenesis. Emerging evidence from animal and human …
Pediatric Trauma
Neural systems subserving valence and arousal during the experience of induced emotions
The circumplex model of affect construes all emotions as linear combinations of 2 independent neurophysiological dimensions, valence and arousal. We used functional magnetic resonance imaging to identify the neural networks subserving valence and arousal, and we assessed, in 10 participants, the associations of the BOLD (blood oxygen level-dependent) response, an indirect index of neural activity, with ratings of valence and arousal during the em…
Measuring Transference Phenomena With fMri
Transference has been a core concept of the psychoanalytic model of the mind ever since its introduction by Freud in 1895 (Laplanche and Pontalis 1967). Throughout the many controversies and vicissitudes of psychoanalytic theory over the past century, the emphasis on transference as a reliable psychological phenomenon and essential ingredient in psychoanalytic treatment has not weakened. Moreover, while many psychoanalytic concepts have either be…
Mapping cortical change across the human life span
Indeterminacy & compromise formation
The meanings of communications between analyst and analysand are replete with alternative interpretations and ambiguity. Interpersonal meaning is inherently indeterminate, and so too is intrapsychic meaning. Indeterminacy of meaning, in fact, is an intrinsic feature of all psychic experience. In the clinical domain, indeterminate meaning is the psychic basis for forming and sustaining neurotic patterns of behaviour. This recognition has important…
Measuring Transference Phenomena With fMri
Transference has been a core concept of the psychoanalytic model of the mind ever since its introduction by Freud in 1895 (Laplanche and Pontalis 1967). Throughout the many controversies and vicissitudes of psychoanalytic theory over the past century, the emphasis on transference as a reliable psychological phenomenon and essential ingredient in psychoanalytic treatment has not weakened. Moreover, while many psychoanalytic concepts have either be…
Indeterminacy & compromise formation
The meanings of communications between analyst and analysand are replete with alternative interpretations and ambiguity. Interpersonal meaning is inherently indeterminate, and so too is intrapsychic meaning. Indeterminacy of meaning, in fact, is an intrinsic feature of all psychic experience. In the clinical domain, indeterminate meaning is the psychic basis for forming and sustaining neurotic patterns of behaviour. This recognition has important…
Profiles of infant communicative behavior
Prior studies of mother-infant interaction have generally used a variable-centered approach to associate face-to-face communication with psychosocial outcomes. Herein, we use a person-centered approach to identify clusters of infants who exhibit similar behavioral profiles during face-to-face communication with their mothers. Four infant communication channels were examined-gaze, facial affect, vocal affect, and head orientation-coded from videot…
Indeterminacy & compromise formation
The meanings of communications between analyst and analysand are replete with alternative interpretations and ambiguity. Interpersonal meaning is inherently indeterminate, and so too is intrapsychic meaning. Indeterminacy of meaning, in fact, is an intrinsic feature of all psychic experience. In the clinical domain, indeterminate meaning is the psychic basis for forming and sustaining neurotic patterns of behaviour. This recognition has important…
Mapping cortical change across the human life span
Measuring Transference Phenomena With fMri
Transference has been a core concept of the psychoanalytic model of the mind ever since its introduction by Freud in 1895 (Laplanche and Pontalis 1967). Throughout the many controversies and vicissitudes of psychoanalytic theory over the past century, the emphasis on transference as a reliable psychological phenomenon and essential ingredient in psychoanalytic treatment has not weakened. Moreover, while many psychoanalytic concepts have either be…
Neural systems subserving valence and arousal during the experience of induced emotions
The circumplex model of affect construes all emotions as linear combinations of 2 independent neurophysiological dimensions, valence and arousal. We used functional magnetic resonance imaging to identify the neural networks subserving valence and arousal, and we assessed, in 10 participants, the associations of the BOLD (blood oxygen level-dependent) response, an indirect index of neural activity, with ratings of valence and arousal during the em…
Pediatric Trauma
Somatoform Pain
Somatoform pain is a highly prevalent, debilitating condition and a tremendous public health problem. Effective treatments for somatoform pain are urgently needed. The etiology of this condition is, however, still unknown. On the basis of a review of recent basic and clinical research, we propose one potential mechanism of symptom formation in somatoform pain and a developmental theory of its pathogenesis. Emerging evidence from animal and human …
Profiles of infant communicative behavior
Prior studies of mother-infant interaction have generally used a variable-centered approach to associate face-to-face communication with psychosocial outcomes. Herein, we use a person-centered approach to identify clusters of infants who exhibit similar behavioral profiles during face-to-face communication with their mothers. Four infant communication channels were examined-gaze, facial affect, vocal affect, and head orientation-coded from videot…
Prenatal exposure to polycyclic aromatic hydrocarbons modifies the effects of early life stress on attention and Thought Problems in late childhood
BACKGROUND: Risk for childhood psychopathology is complex and multifactorial, implicating direct and interacting effects of familial and environmental factors. The role of environmental neurotoxicants in psychiatric risk is of growing concern, including polycyclic aromatic hydrocarbons (PAH), common in air pollution. Prenatal PAH exposure is linked to adverse physical, behavioral, and cognitive outcomes as well as increasing psychiatric risk. It …
Causal effects of psychostimulants on neural connectivity
BACKGROUND: Psychostimulants are frequently used to treat attention-deficit/hyperactivity disorder (ADHD), but side effects are common leading to many patients discontinuing treatment. Identifying neural mechanisms by which psychostimulants attenuate symptoms may guide the development of more refined and tolerable therapeutics. METHODS: We conducted a 12-week, randomized, placebo-controlled trial (RCT) of a long-acting amphetamine, lisdexamfetami…
Prenatal exposure to air pollution is associated with altered brain structure, function, and metabolism in childhood
Background Prenatal exposure to air pollution disrupts cognitive, emotional, and behavioral development. The brain disturbances associated with prenatal air pollution are largely unknown. Methods In this prospective cohort study, we estimated prenatal exposures to fine particulate matter (PM 2.5 ) and polycyclic aromatic hydrocarbons (PAH), and then assessed their associations with measures of brain anatomy, tissue microstructure, neurometabolite…
Using tissue microstructure and multimodal MRI to parse the phenotypic heterogeneity and cellular basis of autism spectrum disorder
BACKGROUND: Identifying the brain bases for phenotypic heterogeneity in Autism Spectrum Disorder (ASD) will advance understanding of its pathogenesis and improve its clinical management. METHODS: We compared Diffusion Tensor Imaging (DTI) indices and connectome measures between 77 ASD and 88 Typically Developing (TD) control participants. We also assessed voxel-wise associations of DTI indices with measures of regional cerebral blood flow (rCBF) …
All we have to fear is fear itself”
438). We organize these findings within a neuroscientific framework and evaluate alternative mechanisms for unconscious exposure. The use of incommensurate outcome measures across exposure paradigms and nonreporting of relevant statistics limited meta-analyses. Despite steps taken to address publication bias, 25.6% of included studies came from a single laboratory. We propose potential clinical applications of these findings. Future research shou…
Brain tissue microstructure in a prospective, longitudinal, population‐based cohort of preterm and term‐born young adults
BACKGROUND: Fifteen million infants annually are born prematurely, placing them at high risk for life-long adverse neurodevelopmental outcomes. Whether brain tissue abnormalities that accompany preterm birth persist into young adulthood and are associated with long-term cognitive or psychiatric outcomes is not known. METHODS: From infancy into young adulthood, we followed a population-based sample of consecutively identified preterm infants and t…
Advancing the treatment of anxiety disorders in transition‐age youth
BACKGROUND: The real-world effectiveness of exposure-based therapies for youth depends on the willingness and ability of young people to tolerate confronting their fears, which can be experienced as highly aversive and create problems with treatment engagement and acceptance. Recently, neuroscientific research on the nonconscious basis of fear has been translated into novel exposure interventions that bypass conscious processing of feared stimuli…
Association of 24‐Hour Ambulatory Blood Pressure During Pregnancy in Adolescents and Young Adults With Measures of Fetal Autonomic Nervous System Development
The autonomic nervous system regulates physiological processes, including cardiovascular functions. Changes in maternal systolic and diastolic blood pressure (SBP; DBP), as well as fetal heart rate and heart rate variability, can serve as indicators of possible risk for adverse perinatal and developmental outcomes. This study examined the association between maternal blood pressure during pregnancy and fetal autonomic nervous system heart rate in…
Psychology (13 works) · Medicine (6 works) · Neuroscience (6 works) · Developmental psychology (5 works) · Functional Brain Connectivity Studies (5 works) · Psychiatry (5 works) · Psychotherapist (5 works) · Clinical Psychology (4 works) · Cognition (4 works) · Cognitive psychology (4 works)