Ming T Tsuang
Biographic Data
| ID | 1662697 |
|---|---|
| NAME | Ming T Tsuang |
| GIVEN NAMES | Ming T |
| FAMILY NAME | Tsuang |
| SIGNATURE | TSUANG M T |
| AFFILIATIONS | University of California San Diego |
| ORCID | 0000-0002-0076-5340 |
| VERIFIED | Yes |
| TOTAL WORKS | 14 |
| TOTAL CITATIONS | 4 |
| AUTHOR COUNT | 14 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 1985 |
| LATEST PUBLICATION YEAR | 2023 |
| H-INDEX | 1 |
Neurobehavioral risk factors influence prevalence and severity of hazardous substance use in youth at genetic and clinical high risk for psychosis
Individuals at genetic and CHR-P have strikingly different patterns of substance use. Factors such as increased neurodevelopmental symptoms (lower IQ, higher rates of ASD) and poorer social functioning in 22qDel may help explain this distinction from substance use patterns observed in CHR-P individuals
The impact of early factors on persistent negative symptoms in youth at clinical high risk for psychosis
In terms of better understanding relationships between early factors and PNS, a prominent factor associated with PNS was premorbid functioning, in particular poor premorbid functioning in later adolescence
Mapping genomic loci implicates genes and synaptic biology in schizophrenia
Abnormally Large Baseline P300 Amplitude Is Associated With Conversion to Psychosis in Clinical High Risk Individuals With a History of Autism: A Pilot Study
Psychosis rates in autism spectrum disorder (ASD) are 5-35% higher than in the general population. The overlap in sensory and attentional processing abnormalities highlights the possibility of related neurobiological substrates. Previous research has shown that several electroencephalography (EEG)-derived event-related potential (ERP) components that are abnormal in schizophrenia, including P300, are also abnormal in individuals at Clinical High …
Evidence of Slow Neural Processing, Developmental Differences and Sensitivity to Cannabis Effects in a Sample at Clinical High Risk for Psychosis From the NAPLS Consortium Assessed With the Human Star…
This is the first study to demonstrate a relationship of startle response latency to psychotic conversion in a CHR population. PPI is an important biomarker that may be sensitive to the neurodevelopmental abnormalities thought to be present in psychosis prone individuals and the effects of cannabis. The significant correlations with age in this sample as well as the finding of greater PPI in CHR cannabis users replicate findings from another larg…
Heritability of SF-36 Among Middle-Age, Middle-Class, Male???Male Twins
OBJECTIVE: We sought to examine the relative importance of genetic and environmental factors for the MOS SF-36; a widely used, valid, and reliable measure of health-related quality of life and to discuss incorporating genetic influences into health services research. DATA SOURCES: Data are from a nationally distributed, nonclinical cohort of 2928 middle age, middle-class, male-male twin members of the Vietnam Era Twin Registry. STUDY DESIGN: This…
A Twin Study of Sexual Behavior in Men
A Twin Study of Depression Symptoms, Hypertension, and Heart Disease in Middle-Aged Men
OBJECTIVE: Epidemiological and clinical studies have established an association between major depression and cardiovascular disease. We utilized a twin design to test whether there are common genetic and environmental risk factors underlying depression symptoms, hypertension and heart disease. METHODS: Association studies were conducted with 6,903 male-male twins from the Vietnam Era Twin Registry who responded to both a 1990 health questionnaire…
Sexual Orientation and Suicidality: A Co-twin Control Study in Adult Men
BACKGROUND: Several recent studies have found a higher lifetime prevalence of suicide attempts in homosexual males compared with heterosexual control subjects or population rates. These studies used either convenience samples, most without controls, or population-based samples in which confounding factors such as depression and substance abuse were not measured. METHODS: This study used twins from the population-based Vietnam Era Twin Registry, H…
Observational Versus Experimental Studies: Would the Results Be Similar
Stanley Cobb Professor of Psychiatry; Harvard Medical School; Director, Harvard Institute of Psychiatric Epidemiology and Genetics; Superintendent and Head; Harvard Department of Psychiatry; Massachusetts Mental Health Center; 74 Fenwood Rd.; Boston, MA
Genetic transmission of major affective disorders: Quantitative models and linkage analyses
We comprehensively reviewed 2 types of studies aimed at specifying the mode of inheritance of major affective disorders: quantitative models and linkage analyses. Quantitative models attempt to represent the genetic mechanism responsible for the familial distribution of a disorder. Despite efforts to refine models by incorporating the bipolar-unipolar distinction or the sex effect, consistent support for a specific mode of transmission has not be…
Genetic transmission of major affective disorders: Quantitative models and linkage analyses
Quantitative models of the genetic transmission of schizophrenia
Quantitative models of the genetic transmission of schizophrenia
Quantitative models of the genetic transmission of schizophrenia
Quantitative models of the genetic transmission of schizophrenia
Genetic transmission of major affective disorders: Quantitative models and linkage analyses
We comprehensively reviewed 2 types of studies aimed at specifying the mode of inheritance of major affective disorders: quantitative models and linkage analyses. Quantitative models attempt to represent the genetic mechanism responsible for the familial distribution of a disorder. Despite efforts to refine models by incorporating the bipolar-unipolar distinction or the sex effect, consistent support for a specific mode of transmission has not be…
Genetic transmission of major affective disorders: Quantitative models and linkage analyses
Sexual Orientation and Suicidality: A Co-twin Control Study in Adult Men
BACKGROUND: Several recent studies have found a higher lifetime prevalence of suicide attempts in homosexual males compared with heterosexual control subjects or population rates. These studies used either convenience samples, most without controls, or population-based samples in which confounding factors such as depression and substance abuse were not measured. METHODS: This study used twins from the population-based Vietnam Era Twin Registry, H…
Observational Versus Experimental Studies: Would the Results Be Similar
Stanley Cobb Professor of Psychiatry; Harvard Medical School; Director, Harvard Institute of Psychiatric Epidemiology and Genetics; Superintendent and Head; Harvard Department of Psychiatry; Massachusetts Mental Health Center; 74 Fenwood Rd.; Boston, MA
A Twin Study of Depression Symptoms, Hypertension, and Heart Disease in Middle-Aged Men
OBJECTIVE: Epidemiological and clinical studies have established an association between major depression and cardiovascular disease. We utilized a twin design to test whether there are common genetic and environmental risk factors underlying depression symptoms, hypertension and heart disease. METHODS: Association studies were conducted with 6,903 male-male twins from the Vietnam Era Twin Registry who responded to both a 1990 health questionnaire…
A Twin Study of Sexual Behavior in Men
Heritability of SF-36 Among Middle-Age, Middle-Class, Male???Male Twins
OBJECTIVE: We sought to examine the relative importance of genetic and environmental factors for the MOS SF-36; a widely used, valid, and reliable measure of health-related quality of life and to discuss incorporating genetic influences into health services research. DATA SOURCES: Data are from a nationally distributed, nonclinical cohort of 2928 middle age, middle-class, male-male twin members of the Vietnam Era Twin Registry. STUDY DESIGN: This…
Evidence of Slow Neural Processing, Developmental Differences and Sensitivity to Cannabis Effects in a Sample at Clinical High Risk for Psychosis From the NAPLS Consortium Assessed With the Human Star…
This is the first study to demonstrate a relationship of startle response latency to psychotic conversion in a CHR population. PPI is an important biomarker that may be sensitive to the neurodevelopmental abnormalities thought to be present in psychosis prone individuals and the effects of cannabis. The significant correlations with age in this sample as well as the finding of greater PPI in CHR cannabis users replicate findings from another larg…
Abnormally Large Baseline P300 Amplitude Is Associated With Conversion to Psychosis in Clinical High Risk Individuals With a History of Autism: A Pilot Study
Psychosis rates in autism spectrum disorder (ASD) are 5-35% higher than in the general population. The overlap in sensory and attentional processing abnormalities highlights the possibility of related neurobiological substrates. Previous research has shown that several electroencephalography (EEG)-derived event-related potential (ERP) components that are abnormal in schizophrenia, including P300, are also abnormal in individuals at Clinical High …
Mapping genomic loci implicates genes and synaptic biology in schizophrenia
Neurobehavioral risk factors influence prevalence and severity of hazardous substance use in youth at genetic and clinical high risk for psychosis
Individuals at genetic and CHR-P have strikingly different patterns of substance use. Factors such as increased neurodevelopmental symptoms (lower IQ, higher rates of ASD) and poorer social functioning in 22qDel may help explain this distinction from substance use patterns observed in CHR-P individuals
The impact of early factors on persistent negative symptoms in youth at clinical high risk for psychosis
In terms of better understanding relationships between early factors and PNS, a prominent factor associated with PNS was premorbid functioning, in particular poor premorbid functioning in later adolescence
Psychology (12 works) · Psychiatry (9 works) · Biology (8 works) · Genetics (8 works) · Medicine (7 works) · Clinical Psychology (6 works) · Genetic Associations and Epidemiology (5 works) · Genetics (4 works) · Prodrome (4 works) · Psychosis (4 works)