Preveena Balakrishnan
Biographic Data
| ID | 167375 |
|---|---|
| NAME | Preveena Balakrishnan |
| GIVEN NAMES | Preveena |
| FAMILY NAME | Balakrishnan |
| SIGNATURE | BALAKRISHNAN P |
| AFFILIATIONS | YR Gaitonde Centre for AIDS Research and Education |
| ORCID | 0000-0002-1710-9155 |
| VERIFIED | Yes |
| TOTAL WORKS | 10 |
| TOTAL CITATIONS | 12 |
| AUTHOR COUNT | 10 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2007 |
| LATEST PUBLICATION YEAR | 2026 |
| H-INDEX | 1 |
Negative influence of age and low baseline CD4 on T helper cell recovery among HIV-infected individuals with fixed-dose combination of tenofovir disoproxil, lamivudine and dolutegravir
Background A discordant immune response (DIR) refers to inadequate CD4 + T cell recovery despite virological suppression after antiretroviral therapy (ART). Methods This study evaluated DIR in HIV-positive patients receiving a first-line regimen of tenofovir disoproxil fumarate, lamivudine and dolutegravir (TLD) at the ART Centre, Saveetha Medical College and Hospital, Chennai, India. DIR was defined as virological suppression to 500 cells/μL wer…
Association of clinical laboratory parameters with latent tuberculosis infection among healthcare workers of primary health centers―A cross-sectional observational study
Healthcare workers (HCWs) are at high risk of tuberculosis (TB) infection due to their continued occupational exposure to patients with active TB disease. The prevalence of latent TB infections (LTBI) among the HCWs of primary healthcare centers (PHCs) has seldom been investigated. PHCs provide effective and preventive medical care largely for the rural population. Comparatively, the HCWs of PHCs are likely to have an increased risk of occupation…
Contestation of State Role in Ethnoscapes: A Contrast Between Community Centrism and Dirigisme in Little India Governance
Attrition in serum anti-Denv antibodies correlates with high anti-Sars-CoV-2 IgG levels and low Denv positivity in mosquito vectors—Findings from a state-wide cluster-randomized community-based study …
The decline in dengue incidence and/or prevalence during the COVID-19 pandemic (2020–22) appears to be attributed to reduced treatment-seeking rates, under-reporting, misdiagnosis, disrupted health services and reduced exposure to mosquito vectors due to prevailing lockdowns. There is limited scientific data on dengue virus (DENV) disease during the COVID-19 pandemic. Here, we conducted a community-based, cross-sectional, cluster-randomized surve…
Plasma CXCL8 and MCP-1 as surrogate plasma biomarkers of latent tuberculosis infection among household contacts–A cross-sectional study
Early detection of latent tuberculosis infection (LTBI) is critical to TB elimination in the current WHO vision of End Tuberculosis Strategy . The study investigates whether detecting plasma cytokines could aid in diagnosing LTBI across household contacts (HHCs) positive for IGRA, HHCs negative for IGRA, and healthy controls. The plasma cytokines were measured using a commercial Bio-Plex Pro Human Cytokine 17-plex assay. Increased plasma CXCL8 an…
Is there synergy in syndemics? Psychosocial conditions and sexual risk among men who have sex with men in India
Syndemic theory describes the clustering and synergistic interaction of disease driven by contextual and social factors, which worsen health outcomes for a population, and has been applied to men who have sex with men (MSM) and their risk for HIV and other sexually transmitted infections. Recent reviews, however, have critiqued prevailing approaches in syndemic studies that assess only additive associations without evaluation of synergy. Followin…
Dropout from care among HIV-infected patients enrolled in care at a tertiary HIV care center in Chennai, India
Long-term follow-up of persons infected with HIV infection is essential to optimize clinical outcomes. However, limited data exist on the rates of dropout (DO) from HIV care and factors associated with DO especially from resource-limited settings. We conducted a retrospective analysis of the data available at YRGCARE, a private HIV care provider in south India that has registered over 15,000 HIV-infected persons since its inception in 1993. We in…
Impact of generic antiretroviral therapy (ART) and free ART programs on time to initiation of ART at a tertiary HIV care center in Chennai, India
Antiretroviral therapy (ART) access in the developing world has improved, but whether increased access has translated to more rapid treatment initiation among those who need it is unknown. We characterize time to ART initiation across three eras of ART availability in Chennai, India (1996-1999: pregeneric; 2000-2003: generic; 2004-2007: free rollout). Between 1996 and 2007, 11,171 patients registered for care at the YR Gaitonde Centre for AIDS Re…
The Emerging HIV Epidemic among Men Who have Sex with Men in Tamil Nadu, India: Geographic Diffusion and Bisexual Concurrency
A randomised control trial of structured interrupted generic antiretroviral therapy versus continuous therapy in HIV-infected individuals in Southern India
This randomised control trial, conducted in Chennai, India, compared structured interrupted therapy (SIT) and continuous therapy (CT) in relation to immunologic and virologic outcomes, adverse events (AEs) and cost of therapy. ART-naïve adult HIV1-infected participants with CD4 counts 50-350 cells/mm(3), and plasma viral load (PVL)>5000 copies/mL were enrolled and placed on Indian-manufactured generic ART: zidovudine(AZT)/stavudine(d4T)+lamivudin…
Is there synergy in syndemics? Psychosocial conditions and sexual risk among men who have sex with men in India
Syndemic theory describes the clustering and synergistic interaction of disease driven by contextual and social factors, which worsen health outcomes for a population, and has been applied to men who have sex with men (MSM) and their risk for HIV and other sexually transmitted infections. Recent reviews, however, have critiqued prevailing approaches in syndemic studies that assess only additive associations without evaluation of synergy. Followin…
A randomised control trial of structured interrupted generic antiretroviral therapy versus continuous therapy in HIV-infected individuals in Southern India
This randomised control trial, conducted in Chennai, India, compared structured interrupted therapy (SIT) and continuous therapy (CT) in relation to immunologic and virologic outcomes, adverse events (AEs) and cost of therapy. ART-naïve adult HIV1-infected participants with CD4 counts 50-350 cells/mm(3), and plasma viral load (PVL)>5000 copies/mL were enrolled and placed on Indian-manufactured generic ART: zidovudine(AZT)/stavudine(d4T)+lamivudin…
The Emerging HIV Epidemic among Men Who have Sex with Men in Tamil Nadu, India: Geographic Diffusion and Bisexual Concurrency
Impact of generic antiretroviral therapy (ART) and free ART programs on time to initiation of ART at a tertiary HIV care center in Chennai, India
Antiretroviral therapy (ART) access in the developing world has improved, but whether increased access has translated to more rapid treatment initiation among those who need it is unknown. We characterize time to ART initiation across three eras of ART availability in Chennai, India (1996-1999: pregeneric; 2000-2003: generic; 2004-2007: free rollout). Between 1996 and 2007, 11,171 patients registered for care at the YR Gaitonde Centre for AIDS Re…
Dropout from care among HIV-infected patients enrolled in care at a tertiary HIV care center in Chennai, India
Long-term follow-up of persons infected with HIV infection is essential to optimize clinical outcomes. However, limited data exist on the rates of dropout (DO) from HIV care and factors associated with DO especially from resource-limited settings. We conducted a retrospective analysis of the data available at YRGCARE, a private HIV care provider in south India that has registered over 15,000 HIV-infected persons since its inception in 1993. We in…
Is there synergy in syndemics? Psychosocial conditions and sexual risk among men who have sex with men in India
Syndemic theory describes the clustering and synergistic interaction of disease driven by contextual and social factors, which worsen health outcomes for a population, and has been applied to men who have sex with men (MSM) and their risk for HIV and other sexually transmitted infections. Recent reviews, however, have critiqued prevailing approaches in syndemic studies that assess only additive associations without evaluation of synergy. Followin…
Plasma CXCL8 and MCP-1 as surrogate plasma biomarkers of latent tuberculosis infection among household contacts–A cross-sectional study
Early detection of latent tuberculosis infection (LTBI) is critical to TB elimination in the current WHO vision of End Tuberculosis Strategy . The study investigates whether detecting plasma cytokines could aid in diagnosing LTBI across household contacts (HHCs) positive for IGRA, HHCs negative for IGRA, and healthy controls. The plasma cytokines were measured using a commercial Bio-Plex Pro Human Cytokine 17-plex assay. Increased plasma CXCL8 an…
Attrition in serum anti-Denv antibodies correlates with high anti-Sars-CoV-2 IgG levels and low Denv positivity in mosquito vectors—Findings from a state-wide cluster-randomized community-based study …
The decline in dengue incidence and/or prevalence during the COVID-19 pandemic (2020–22) appears to be attributed to reduced treatment-seeking rates, under-reporting, misdiagnosis, disrupted health services and reduced exposure to mosquito vectors due to prevailing lockdowns. There is limited scientific data on dengue virus (DENV) disease during the COVID-19 pandemic. Here, we conducted a community-based, cross-sectional, cluster-randomized surve…
Association of clinical laboratory parameters with latent tuberculosis infection among healthcare workers of primary health centers―A cross-sectional observational study
Healthcare workers (HCWs) are at high risk of tuberculosis (TB) infection due to their continued occupational exposure to patients with active TB disease. The prevalence of latent TB infections (LTBI) among the HCWs of primary healthcare centers (PHCs) has seldom been investigated. PHCs provide effective and preventive medical care largely for the rural population. Comparatively, the HCWs of PHCs are likely to have an increased risk of occupation…
Contestation of State Role in Ethnoscapes: A Contrast Between Community Centrism and Dirigisme in Little India Governance
Negative influence of age and low baseline CD4 on T helper cell recovery among HIV-infected individuals with fixed-dose combination of tenofovir disoproxil, lamivudine and dolutegravir
Background A discordant immune response (DIR) refers to inadequate CD4 + T cell recovery despite virological suppression after antiretroviral therapy (ART). Methods This study evaluated DIR in HIV-positive patients receiving a first-line regimen of tenofovir disoproxil fumarate, lamivudine and dolutegravir (TLD) at the ART Centre, Saveetha Medical College and Hospital, Chennai, India. DIR was defined as virological suppression to 500 cells/μL wer…
Medicine (8 works) · HIV/AIDS Research and Interventions (6 works) · Internal Medicine (6 works) · Demography (4 works) · HIV Research and Treatment (4 works) · Immunology (4 works) · Antiretroviral therapy (3 works) · Environmental health (3 works) · HIV, Drug Use, Sexual Risk (3 works) · HIV/AIDS drug development and treatment (3 works)