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Tomohiro Nakao

Biographic Data

ID171282
NAMETomohiro Nakao
GIVEN NAMESTomohiro
FAMILY NAMENakao
SIGNATURENAKAO T
AFFILIATIONSKyushu University
ORCID0000-0002-4420-6903
VERIFIEDYes
TOTAL WORKS17
TOTAL CITATIONS0
WORKS AS AUTHOR17
WORKS AS EDITOR0
FIRST PUBLICATION YEAR2017
LATEST PUBLICATION YEAR2026
H-INDEX0
  • Case Report

    Open Access•Makoto Kawahito, Keitaro Murayama et al.•ARTICLE•Frontiers in Psychiatry•2026

    Making perceptual antecedents and diurnal moderators explicit based on chain analysis enabled a targeted, medication-free intervention that produced clinically meaningful reductions in behavior and urges. A chain-guided behavioral framework may help personalize treatment for SPD and related body-focused repetitive behaviors

  • Earlier age at onset is associated with more severe sensory phenomena in drug-naive, comorbidity-free patients with obsessive-compulsive disorder

    Open Access•Makoto Kawahito, Keitaro Murayama et al.•ARTICLE•Frontiers in Psychiatry•2026

    Earlier onset of OCD was associated with more severe SP after adjustment for clinical covariates. These findings may be consistent with a neurodevelopmental contribution to SP severity in OCD. Further longitudinal and qualitative studies on SP are warranted

  • Reduced resting-state functional connectivity between insula and inferior frontal gyrus and superior temporal gyrus in hoarding disorder

    Open Access•Kenta KATŌ, Hirofumi Tomiyama et al.•ARTICLE•Frontiers in Psychiatry•2024

    Although the clinical implication is uncertain, our results suggest that patients with HD have resting-state functional alterations between the insula and IFG and STG, corresponding with the results of previous fMRI studies. These findings provide new insight into the neurobiological basis of HD

  • Decision-making deficits in obsessive-compulsive disorder are associated with abnormality of recency and response consistency parameter in prospect valence learning model

    Open Access•Keitaro Murayama, Hirofumi Tomiyama et al.•ARTICLE•Frontiers in Psychiatry•2023

    Our detailed analysis of the decision-making deficit in OCD suggests that the most recent outcome has a small influence on the expectancy of prospect valence, as indicated by the lower recency parameter, and is characterized by more impulsive choices, as indicated by the lower consistency parameter

  • Day Intervention Program for Family Members of Hikikomori Sufferers

    Open Access•Hiroaki Kubo, Hiromi Urata et al.•ARTICLE•Frontiers in Psychiatry•2023

    We could not draw general conclusions on the effectiveness of the program due to the study discontinuation. Nevertheless, this study indicates the necessity for revision of the program to improve family members' confidence in engaging with hikikomori sufferers, with safer approaching by families

  • Inverse Association Between Resting-State Putamen Activity and Iowa Gambling Task Performance in Patients With Obsessive-Compulsive Disorder and Control Subjects

    Open Access•Suguru Hasuzawa, Hirofumi Tomiyama et al.•ARTICLE•Frontiers in Psychiatry•2022

    These findings in unmedicated patients demonstrate the importance of resting-state putamen activity for decision-making deficit associated with OCD, as measured by IGT. The inverse correlation may be explained by the hypersensitive response of the putamen in patients with OCD

  • Decreased Bold signals elicited by 40-Hz auditory stimulation of the right primary auditory cortex in bipolar disorder

    Open Access•Hiroshi Okamoto, Toshiaki Onitsuka et al.•ARTICLE•Frontiers in Psychiatry•2022

    The observed decrease in BOLD signal patterns in the right primary auditory cortex during 40-Hz ASSR may be a potential biomarker option for bipolar disorder

  • Psychological Traits of Patients With Depression Comorbid With Chronic Pain

    Open Access•Koji Fujimoto, Masako Hosoi et al.•ARTICLE•Frontiers in Psychiatry•2022

    Complaint and competitive traits were shown to be related to chronic pain in psychiatric settings. Further study will allow us to design multidimensional approach for patients suffering from depression

  • The Impact of Gender and Age Differences and Infectious Disease Symptoms on Psychological Distress in Quarantined Asymptomatic or Mildly Ill Covid-19 Patients in Japan

    Open Access•Keitaro Murayama, Hideharu Tatebayashi et al.•ARTICLE•International Journal of…•2022

    Quarantine imposed due to COVID-19 infection can exacerbate psychological distress, and it is important for a public mental health agency to identify factors that are predictive of high psychological distress in such situation. The aim of this study was to investigate whether gender, age, and the presence or absence of infectious disease symptoms affected psychological distress among asymptomatic or mildly ill COVID-19 patients who were quarantin…

  • Eye Movement Abnormalities in Major Depressive Disorder

    Open Access•Junichi Takahashi, Yoji Hirano et al.•ARTICLE•Frontiers in Psychiatry•2021

    Background: Despite their high lifetime prevalence, major depressive disorder (MDD) is often difficult to diagnose, and there is a need for useful biomarkers for the diagnosis of MDD. Eye movements are considered a non-invasive potential biomarker for the diagnosis of psychiatric disorders such as schizophrenia. However, eye movement deficits in MDD remain unclear. Thus, we evaluated detailed eye movement measurements to validate its usefulness a…

  • Aberrant Resting-State Cerebellar-Cerebral Functional Connectivity in Unmedicated Patients With Obsessive-Compulsive Disorder

    Open Access•Keitaro Murayama, Hirofumi Tomiyama et al.•ARTICLE•Frontiers in Psychiatry•2021

    Background: Although abnormality of cerebellar-cerebral functional connectivity at rest in obsessive-compulsive disorder (OCD) has been hypothesized, only a few studies have investigated the neural mechanism. To verify the findings of previous studies, a large sample of patients with OCD was studied because OCD shows possible heterogeneity. Methods: Forty-seven medication-free patients with OCD and 62 healthy controls (HCs) underwent resting-stat…

  • Mental Health Difficulties and Countermeasures during the Coronavirus Disease Pandemic in Japan

    Open Access•Tomohiro Nakao, Keitaro Murayama et al.•ARTICLE•International Journal of…•2021

    The number of people with coronavirus disease (COVID-19) has been increasing worldwide. Anxiety about potential infection, fear of severe illness, death, economic problems, and loneliness and isolation brought on by social distancing are increasingly being experienced by people. Therefore, it is imperative to address and improve such mental health-related problems during COVID-19. We aimed to investigate the current mental health care and psychol…

  • Neurophysiological Face Processing Deficits in Patients With Chronic Schizophrenia

    Open Access•Naotoshi Ohara, Yoji Hirano et al.•ARTICLE•Frontiers in Psychiatry•2020

    The present study showed specific reductions in the M170 response to human faces in patients with SZ. Our findings could suggest that SZ is characterized by face processing deficits that are associated with the severity of negative symptoms. Thus, we suggest that social cognition impairments in SZ might, at least in part, be caused by this functional face processing deficit

  • Impacts of Stressful Life Events and Traumatic Experiences on Onset of Obsessive-Compulsive Disorder

    Open Access•Keitaro Murayama, Tomohiro Nakao et al.•ARTICLE•Frontiers in Psychiatry•2020

    Not a few patients with obsessive-compulsive disorder (OCD) have experienced events that affected the onset. The onset of OCD is not limited to the original meaning of trauma; rather, traumatic experiences such as unexpected exposure to contaminants or various stressful life events often cause the onset of OCD. It would be useful to understand the experiences surrounding the onset, including stressful life events and traumatic experiences, for co…

  • Relevance of hoarding behavior and the traits of developmental disorders among university students

    Open Access•Kosuke Kajitani, Rikako Tsuchimoto et al.•ARTICLE•BioPsychoSocial Medicine•2019

    Previous studies have shown that hoarding behavior usually starts at a subclinical level in early adolescence and gradually worsens; however, a limited number of studies have examined the prevalence of hoarding behavior and its association with developmental disorders in young adults. The aims of this study were to estimate the prevalence of hoarding behavior and to identify correlations between hoarding behavior and developmental disorder traits…

  • A transcultural study of hoarding disorder

    Open Access•Ashley E Nordsletten, Lorena Fernández De La Cruz et al.•ARTICLE•Transcultural Psychiatry•2018•References: 54

    Though problematic hoarding is believed to be a universal human behavior, investigations of clinically-defined hoarding disorder (HD) have been confined almost exclusively to Western countries. The current investigation sought to describe and directly compare the features of individuals meeting diagnostic criteria for HD across four distinct cultural settings. Participants were 82 individuals meeting DSM-5 diagnostic criteria for HD, recruited an…

  • Clinical features of Japanese patients with Hording Disorder

    Open Access•Tomohiro Nakao, Satoshi Yamada et al.•ARTICLE•Frontiers in Psychiatry•2017

    Frontiers Events is a rapidly growing calendar management system dedicated to the scheduling of academic events. This includes announcements and invitations, participant listings and search functionality, abstract handling and publication, related events and post-event exchanges. Whether an organizer or participant, make your event a Frontiers Event

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  • Clinical features of Japanese patients with Hording Disorder

    Open Access•Tomohiro Nakao, Satoshi Yamada et al.•ARTICLE•Frontiers in Psychiatry•2017

    Frontiers Events is a rapidly growing calendar management system dedicated to the scheduling of academic events. This includes announcements and invitations, participant listings and search functionality, abstract handling and publication, related events and post-event exchanges. Whether an organizer or participant, make your event a Frontiers Event

  • A transcultural study of hoarding disorder

    Open Access•Ashley E Nordsletten, Lorena Fernández De La Cruz et al.•ARTICLE•Transcultural Psychiatry•2018•References: 54

    Though problematic hoarding is believed to be a universal human behavior, investigations of clinically-defined hoarding disorder (HD) have been confined almost exclusively to Western countries. The current investigation sought to describe and directly compare the features of individuals meeting diagnostic criteria for HD across four distinct cultural settings. Participants were 82 individuals meeting DSM-5 diagnostic criteria for HD, recruited an…

  • Relevance of hoarding behavior and the traits of developmental disorders among university students

    Open Access•Kosuke Kajitani, Rikako Tsuchimoto et al.•ARTICLE•BioPsychoSocial Medicine•2019

    Previous studies have shown that hoarding behavior usually starts at a subclinical level in early adolescence and gradually worsens; however, a limited number of studies have examined the prevalence of hoarding behavior and its association with developmental disorders in young adults. The aims of this study were to estimate the prevalence of hoarding behavior and to identify correlations between hoarding behavior and developmental disorder traits…

  • Neurophysiological Face Processing Deficits in Patients With Chronic Schizophrenia

    Open Access•Naotoshi Ohara, Yoji Hirano et al.•ARTICLE•Frontiers in Psychiatry•2020

    The present study showed specific reductions in the M170 response to human faces in patients with SZ. Our findings could suggest that SZ is characterized by face processing deficits that are associated with the severity of negative symptoms. Thus, we suggest that social cognition impairments in SZ might, at least in part, be caused by this functional face processing deficit

  • Impacts of Stressful Life Events and Traumatic Experiences on Onset of Obsessive-Compulsive Disorder

    Open Access•Keitaro Murayama, Tomohiro Nakao et al.•ARTICLE•Frontiers in Psychiatry•2020

    Not a few patients with obsessive-compulsive disorder (OCD) have experienced events that affected the onset. The onset of OCD is not limited to the original meaning of trauma; rather, traumatic experiences such as unexpected exposure to contaminants or various stressful life events often cause the onset of OCD. It would be useful to understand the experiences surrounding the onset, including stressful life events and traumatic experiences, for co…

  • Eye Movement Abnormalities in Major Depressive Disorder

    Open Access•Junichi Takahashi, Yoji Hirano et al.•ARTICLE•Frontiers in Psychiatry•2021

    Background: Despite their high lifetime prevalence, major depressive disorder (MDD) is often difficult to diagnose, and there is a need for useful biomarkers for the diagnosis of MDD. Eye movements are considered a non-invasive potential biomarker for the diagnosis of psychiatric disorders such as schizophrenia. However, eye movement deficits in MDD remain unclear. Thus, we evaluated detailed eye movement measurements to validate its usefulness a…

  • Aberrant Resting-State Cerebellar-Cerebral Functional Connectivity in Unmedicated Patients With Obsessive-Compulsive Disorder

    Open Access•Keitaro Murayama, Hirofumi Tomiyama et al.•ARTICLE•Frontiers in Psychiatry•2021

    Background: Although abnormality of cerebellar-cerebral functional connectivity at rest in obsessive-compulsive disorder (OCD) has been hypothesized, only a few studies have investigated the neural mechanism. To verify the findings of previous studies, a large sample of patients with OCD was studied because OCD shows possible heterogeneity. Methods: Forty-seven medication-free patients with OCD and 62 healthy controls (HCs) underwent resting-stat…

  • Mental Health Difficulties and Countermeasures during the Coronavirus Disease Pandemic in Japan

    Open Access•Tomohiro Nakao, Keitaro Murayama et al.•ARTICLE•International Journal of…•2021

    The number of people with coronavirus disease (COVID-19) has been increasing worldwide. Anxiety about potential infection, fear of severe illness, death, economic problems, and loneliness and isolation brought on by social distancing are increasingly being experienced by people. Therefore, it is imperative to address and improve such mental health-related problems during COVID-19. We aimed to investigate the current mental health care and psychol…

  • Inverse Association Between Resting-State Putamen Activity and Iowa Gambling Task Performance in Patients With Obsessive-Compulsive Disorder and Control Subjects

    Open Access•Suguru Hasuzawa, Hirofumi Tomiyama et al.•ARTICLE•Frontiers in Psychiatry•2022

    These findings in unmedicated patients demonstrate the importance of resting-state putamen activity for decision-making deficit associated with OCD, as measured by IGT. The inverse correlation may be explained by the hypersensitive response of the putamen in patients with OCD

  • Decreased Bold signals elicited by 40-Hz auditory stimulation of the right primary auditory cortex in bipolar disorder

    Open Access•Hiroshi Okamoto, Toshiaki Onitsuka et al.•ARTICLE•Frontiers in Psychiatry•2022

    The observed decrease in BOLD signal patterns in the right primary auditory cortex during 40-Hz ASSR may be a potential biomarker option for bipolar disorder

  • Psychological Traits of Patients With Depression Comorbid With Chronic Pain

    Open Access•Koji Fujimoto, Masako Hosoi et al.•ARTICLE•Frontiers in Psychiatry•2022

    Complaint and competitive traits were shown to be related to chronic pain in psychiatric settings. Further study will allow us to design multidimensional approach for patients suffering from depression

  • The Impact of Gender and Age Differences and Infectious Disease Symptoms on Psychological Distress in Quarantined Asymptomatic or Mildly Ill Covid-19 Patients in Japan

    Open Access•Keitaro Murayama, Hideharu Tatebayashi et al.•ARTICLE•International Journal of…•2022

    Quarantine imposed due to COVID-19 infection can exacerbate psychological distress, and it is important for a public mental health agency to identify factors that are predictive of high psychological distress in such situation. The aim of this study was to investigate whether gender, age, and the presence or absence of infectious disease symptoms affected psychological distress among asymptomatic or mildly ill COVID-19 patients who were quarantin…

  • Decision-making deficits in obsessive-compulsive disorder are associated with abnormality of recency and response consistency parameter in prospect valence learning model

    Open Access•Keitaro Murayama, Hirofumi Tomiyama et al.•ARTICLE•Frontiers in Psychiatry•2023

    Our detailed analysis of the decision-making deficit in OCD suggests that the most recent outcome has a small influence on the expectancy of prospect valence, as indicated by the lower recency parameter, and is characterized by more impulsive choices, as indicated by the lower consistency parameter

  • Day Intervention Program for Family Members of Hikikomori Sufferers

    Open Access•Hiroaki Kubo, Hiromi Urata et al.•ARTICLE•Frontiers in Psychiatry•2023

    We could not draw general conclusions on the effectiveness of the program due to the study discontinuation. Nevertheless, this study indicates the necessity for revision of the program to improve family members' confidence in engaging with hikikomori sufferers, with safer approaching by families

  • Reduced resting-state functional connectivity between insula and inferior frontal gyrus and superior temporal gyrus in hoarding disorder

    Open Access•Kenta KATŌ, Hirofumi Tomiyama et al.•ARTICLE•Frontiers in Psychiatry•2024

    Although the clinical implication is uncertain, our results suggest that patients with HD have resting-state functional alterations between the insula and IFG and STG, corresponding with the results of previous fMRI studies. These findings provide new insight into the neurobiological basis of HD

  • Case Report

    Open Access•Makoto Kawahito, Keitaro Murayama et al.•ARTICLE•Frontiers in Psychiatry•2026

    Making perceptual antecedents and diurnal moderators explicit based on chain analysis enabled a targeted, medication-free intervention that produced clinically meaningful reductions in behavior and urges. A chain-guided behavioral framework may help personalize treatment for SPD and related body-focused repetitive behaviors

  • Earlier age at onset is associated with more severe sensory phenomena in drug-naive, comorbidity-free patients with obsessive-compulsive disorder

    Open Access•Makoto Kawahito, Keitaro Murayama et al.•ARTICLE•Frontiers in Psychiatry•2026

    Earlier onset of OCD was associated with more severe SP after adjustment for clinical covariates. These findings may be consistent with a neurodevelopmental contribution to SP severity in OCD. Further longitudinal and qualitative studies on SP are warranted

Medicine (14 works) · Psychology (14 works) · Psychiatry (12 works) · Obsessive-Compulsive Spectrum Disorders (10 works) · Clinical Psychology (7 works) · Cognition (7 works) · Clinical Psychology (6 works) · Internal Medicine (6 works) · Neuroscience (6 works) · Audiology (5 works)

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