Saad B Omer
Biographic Data
| ID | 1737186 |
|---|---|
| NAME | Saad B Omer |
| GIVEN NAMES | Saad B |
| FAMILY NAME | Omer |
| SIGNATURE | OMER S B |
| AFFILIATIONS | Yale University |
| ORCID | 0000-0002-5383-3474 |
| VERIFIED | Yes |
| TOTAL WORKS | 54 |
| TOTAL CITATIONS | 53 |
| AUTHOR COUNT | 54 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2005 |
| LATEST PUBLICATION YEAR | 2025 |
| H-INDEX | 4 |
Validation of polyester nasal swabs for post-mortem Sars-CoV-2 diagnosis in Karachi, Pakistan
Background: The COVID-19 pandemic has significantly impacted global health, with low- and middle-income countries (LMICs) facing unique healthcare challenges. Polyester nasal swabs stored in dry tubes have emerged as a cost-effective and scalable method for routine testing of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We aimed to assess the prevalence of SARS-CoV-2 among deceased individuals in an urban slum in Karachi, Pakista…
Change in influenza vaccine uptake among adults in the United States from May 2020 to October 2024
Influenza vaccines are essential against the spread of influenza virus. In the United States, the Centers for Disease Control and Prevention (CDC) recommends vaccination to all eligible individuals over 6 months of age; however, uptake remains suboptimal nationally. We do not fully understand the current nuances of influenza vaccine uptake, nor how it has been affected by the coronavirus disease 2019 (COVID-19) pandemic. From 2020-2024, we conduc…
Change in confidence in public health entities among US adults between 2020–2024
The COVID-19 pandemic introduced significant uncertainty among Americans, and eroded trust in US health entities and institutions. This study describes a longitudinal assessment of Americans’ change in confidence in these public health entities from 2020 to 2024. We conducted four surveys assessing confidence in public health entities among US adults conducted between February 2020 and October 2024. Surveys were hosted by CloudResearch and admini…
Evaluating the burden of respiratory tract infections among mortality cases in Karachi, Pakistan
Background: Respiratory tract infections (RTIs) significantly impact global health, but particularly affect low- and middle-income countries. They contribute to morbidity and mortality, especially among vulnerable populations. We evaluated the burden of RTIs in mortality cases in an urban slum of Karachi, Pakistan, during the post-COVID-19 pandemic period. Methods: We conducted a prospective observational study from September 2022 to October 2023…
Determining the cause of death through mortality surveillance using verbal autopsy in Karachi, Pakistan
Background: In Pakistan, cultural and religious beliefs restrict autopsies, limiting their prevalence. Additionally, many deaths occur at home, outside of hospital systems, making cause-of-death (CoD) determination challenging. This study aims to overcome these challenges by using a community-based verbal autopsy approach in Karachi to identify CoD. Methods: The research was conducted in two peri-urban communities within the Health Demographic Si…
Moral foundations messaging to improve vaccine attitudes
The uptake of routine childhood vaccinations has declined globally since the start of the COVID-19 pandemic, due in part to increased vaccine hesitancy among parents. The Moral Foundations Theory proposes six foundations which can be targeted to increase vaccine uptake. In this study, we tested whether a post by UNICEF with a purity violation message could affect vaccine attitudes among parents in Argentina, where routine immunization coverage ha…
Behavioral interventions for vaccination uptake
Validation of the Vaccination Trust Indicator (VTI) in a multi-country survey of adult vaccination attitudes
Improved uptake of adult vaccinations could substantially reduce the burden of infectious disease worldwide, however very few countries achieve high coverage of recommended adult vaccinations. Vaccine hesitancy is an important driver of low vaccine uptake among adults but no measure currently exists to capture general vaccination attitudes in this population accurately and efficiently. We utilize data from two surveys of adult vaccine attitudes a…
Persuasive Covid-19 vaccination campaigns on Facebook and nationwide vaccination coverage in Ukraine, India, and Pakistan
Social media platforms have a wide and influential reach, and as such provide an opportunity to increase vaccine uptake. To date, there is no large-scale, robust evidence on the offline effects of online messaging campaigns. We aimed to test whether pre-tested, persuasive messaging campaigns from UNICEF, disseminated on Facebook, influenced COVID-19 vaccine uptake in Ukraine, India, and Pakistan. In Ukraine, we deployed a stepped-wedge randomized…
Moral foundations and HPV vaccine acceptance in the United States
Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in children younger than 5 years in 2019
BACKGROUND: Respiratory syncytial virus (RSV) is the most common cause of acute lower respiratory infection in young children. We previously estimated that in 2015, 33·1 million episodes of RSV-associated acute lower respiratory infection occurred in children aged 0-60 months, resulting in a total of 118 200 deaths worldwide. Since then, several community surveillance studies have been done to obtain a more precise estimation of RSV associated co…
Drivers of Covid-19 policy stringency in 175 countries and territories
Background: New data on COVID-19 may influence the stringency of containment policies, but these potential effect are not understood. We aimed to understand the associations of new COVID-19 cases and deaths with policy stringency globally and regionally. Methods: We modelled the marginal effects of new COVID-19 cases and deaths on policy stringency (scored 0-100) in 175 countries and territories, adjusting for gross domestic product (GDP) per cap…
Association of community engagement with vaccination confidence and uptake
Background: The 2014-2016 Ebola epidemic disrupted childhood immunization in Sierra Leone, Liberia, and Guinea. After the epidemic, the Government of Sierra Leone prioritized community engagement to increase vaccination confidence and uptake. To support these efforts, we examined potential drivers of vaccination confidence and uptake in Sierra Leone. Methods: We conducted a population-based household survey with primary caregivers of children in …
Covid-19 vaccine perceptions in the initial phases of US vaccine roll-out
Our findings can inform the development of interventions where individuals determine the accuracy of vaccine information, and communications campaigns to improve COVID-19 vaccine perceptions, early in the vaccine timeline. Such efforts can increase individual- and population-level awareness of accurate and scientifically sound information regarding vaccines and thereby improve attitudes about vaccines, especially in the early phases of vaccine ro…
MomsTalkShots, tailored educational app, improves vaccine attitudes
Registered at Clinicaltrials.gov on 13/09/2016 (registration number: NCT02898688)
Educational and economic returns to cognitive ability in low- and middle-income countries
Covid-19 vaccine acceptance and hesitancy in low- and middle-income countries
Widespread acceptance of COVID-19 vaccines is crucial for achieving sufficient immunization coverage to end the global pandemic, yet few studies have investigated COVID-19 vaccination attitudes in lower-income countries, where large-scale vaccination is just beginning. We analyze COVID-19 vaccine acceptance across 15 survey samples covering 10 low- and middle-income countries (LMICs) in Asia, Africa and South America, Russia (an upper-middle-inco…
Methodological frontiers in vaccine safety
While vaccines are rigorously tested for safety and efficacy in clinical trials, these trials do not include enough subjects to detect rare adverse events, and they generally exclude special populations such as pregnant women. It is therefore necessary to conduct postmarketing vaccine safety assessments using observational data sources. The study of rare events has been enabled in through large linked databases and distributed data networks, in c…
Leveraging HIV Care Infrastructures for Integrated Chronic Disease and Pandemic Management in Sub-Saharan Africa
In Sub-Saharan Africa, communicable and other tropical infectious diseases remain major challenges apart from the continuing HIV/AIDS epidemic. Recognition and prevalence of non-communicable diseases have risen throughout Africa, and the reimagining of healthcare delivery is needed to support communities coping with not only with HIV, tuberculosis, and COVID-19, but also cancer, cardiovascular disease, diabetes, and depression. Many non-communica…
Determinants of Covid-19 vaccine acceptance in the US
BACKGROUND: The COVID-19 pandemic continues to adversely affect the U.S., which leads globally in total cases and deaths. As COVID-19 vaccines are under development, public health officials and policymakers need to create strategic vaccine-acceptance messaging to effectively control the pandemic and prevent thousands of additional deaths. METHODS: Using an online platform, we surveyed the U.S. adult population in May 2020 to understand risk perce…
Patient Decision Making Related to Maternal and Childhood Vaccines
Immunization is one of the most effective ways to prevent infectious diseases. However, vaccination rates are suboptimal in the United States. Obstetric providers are critical in influencing vaccine decision making among pregnant women, as trust between a patient and provider may facilitate willingness to accept vaccination. Little is known about how power between a patient and provider affects vaccine acceptance. This study explored pregnant wom…
Latent Class Analysis of Maternal Vaccine Attitudes and Beliefs
Background. Maternal vaccine coverage is suboptimal, and a substantial proportion of parents have concerns about vaccines. Most parents seek out vaccine information during and immediately after their first pregnancy. No study to our knowledge has analyzed survey data to identify homogeneous groups of pregnant women based on their vaccine attitudes and beliefs. Aims. To identify homogeneity among groups of pregnant women based on their vaccine att…
Effectiveness of Gas and Chimney Biomass Stoves for Reducing Household Air Pollution Pregnancy Exposure in Guatemala
Household air pollution (HAP) due to solid fuel use during pregnancy is associated with adverse birth outcomes. The real-life effectiveness of clean cooking interventions has been disappointing overall yet variable, but the sociodemographic determinants are not well described. We measured personal 24-h PM 2.5 (particulate matter n = 218) gravimetrically with Teflon filter, impactor, and personal pump setups. To estimate the effectiveness of ownin…
Shouting at each other into the void
In 2015, California passed Senate Bill 277 and became the third state in the United States to ban all nonmedical exemptions from school immunization requirements, effectively prohibiting religious and personal belief exemptions. This attracted grassroots opposition and considerable debate among vaccine hesitant factions online. This mixed-methods study used quantitative linguistic analysis, semantic network analysis, and content analysis techniqu…
Ten considerations for effectively managing the Covid-19 transition
Governments around the world have implemented measures to manage the transmission of coronavirus disease 2019 (COVID-19). While the majority of these measures are proving effective, they have a high social and economic cost, and response strategies are being adjusted. The World Health Organization (WHO) recommends that communities should have a voice, be informed and engaged, and participate in this transition phase. We propose ten considerations…
Association of moral values with vaccine hesitancy
Ten considerations for effectively managing the Covid-19 transition
Governments around the world have implemented measures to manage the transmission of coronavirus disease 2019 (COVID-19). While the majority of these measures are proving effective, they have a high social and economic cost, and response strategies are being adjusted. The World Health Organization (WHO) recommends that communities should have a voice, be informed and engaged, and participate in this transition phase. We propose ten considerations…
Spatial Clustering of HIV Prevalence in Atlanta, Georgia and Population Characteristics Associated with Case Concentrations
Trends in Personal Belief Exemption Rates Among Alternative Private Schools
Objectives. To evaluate trends in rates of personal belief exemptions (PBEs) to immunization requirements for private kindergartens in California that practice alternative educational methods. Methods. We used California Department of Public Health data on kindergarten PBE rates from 2000 to 2014 to compare annual average increases in PBE rates between schools. Results. Alternative schools had an average PBE rate of 8.7%, compared with 2.1% among…
Exemptions to School Immunization Requirements
Objectives. Our goal was to determine whether school-level variability in implementation of immunization requirements is associated with the likelihood of a child having received an exemption to school immunization requirements. Methods. We surveyed 1000 school immunization personnel in Colorado, Massachusetts, Missouri, and Washington. We explored associations between school implementation of immunization requirements and the likelihood of a chi…
Shouting at each other into the void
In 2015, California passed Senate Bill 277 and became the third state in the United States to ban all nonmedical exemptions from school immunization requirements, effectively prohibiting religious and personal belief exemptions. This attracted grassroots opposition and considerable debate among vaccine hesitant factions online. This mixed-methods study used quantitative linguistic analysis, semantic network analysis, and content analysis techniqu…
Moral foundations and HPV vaccine acceptance in the United States
California’s Senate Bill 277
Objectives. To understand the experiences of local health jurisdictions with Senate Bill 277 (SB277), the California law that eliminated nonmedical vaccine exemptions for public- and private-school entry. Methods. We conducted semistructured telephone interviews with health officers and local health department (LHD) staff in California between August and September 2017. Results. Two overall themes emerged: (1) vague legislative and regulatory lan…
Use of Fees to Discourage Nonmedical Exemptions to School Immunization Laws in US States
Recent outbreaks of vaccine-preventable diseases in the United States have renewed public discourse about state vaccine mandates for children entering schools. We review the use of taxes, fines, and fees as financial disincentives in public health. We argue that adding processing fees to a comprehensive set of administrative requirements for obtaining exemptions will avoid the use of taxpayer funding for exemption processing and will help tilt th…
Factors Associated With Refusal of Childhood Vaccines Among Parents of School-aged Children
BACKGROUND: The rate of nonmedical exemptions to school immunization requirements has been increasing, and children with exemptions have contributed to outbreaks of vaccine-preventable diseases. OBJECTIVES: To determine why parents claim nonmedical exemptions and to explore differences in perceptions of vaccines and vaccine information sources between parents of exempt and fully vaccinated children. DESIGN: Case-control study. SETTING: Colorado, …
Exemptions to School Immunization Requirements
Objectives. Our goal was to determine whether school-level variability in implementation of immunization requirements is associated with the likelihood of a child having received an exemption to school immunization requirements. Methods. We surveyed 1000 school immunization personnel in Colorado, Massachusetts, Missouri, and Washington. We explored associations between school implementation of immunization requirements and the likelihood of a chi…
Support for immunization registries among parents of vaccinated and unvaccinated school-aged children
Parental support for registries was relatively high. Parental support for immunization registries may increase with greater parental awareness of the risks of vaccine preventable diseases and utility of vaccination
Local public health workers' perceptions toward responding to an influenza pandemic
The perceived risk among public health workers was shown to be associated with several factors peripheral to the actual hazard of this event. These risk perception modifiers and the knowledge gaps identified serve as barriers to pandemic influenza response and must be specifically addressed to enable effective local public health response to this significant threat
Economic analysis of childhood pneumonia in Northern Pakistan
OBJECTIVES: This study estimates household costs for treatment of pneumonia, severe pneumonia and very severe febrile disease. Combined with reported costs from the health care provider perspective, an estimate of the overall financial burden of these diseases has been developed for the Northern Areas of Pakistan. METHODS: Data on the duration and economic implications of the illnesses for households were collected from caretakers of children und…
Vaccine Refusal, Mandatory Immunization, and the Risks of Vaccine-Preventable Diseases
Vaccines are among the most effective prevention tools available to clinicians. However, the success of an immunization program depends on high rates of acceptance and coverage. There is evidence of an increase in vaccine refusal in the United States and of geographic clustering of refusals that results in outbreaks. Children with exemptions from school immunization requirements (a measure of vaccine refusal) are at increased risk for measles and…
Congenital rubella syndrome and autism spectrum disorder prevented by rubella vaccination - United States, 2001-2010
We estimate that rubella vaccination prevented substantial numbers of CRS and ASD cases in the United States from 2001 through 2010. These findings provide additional incentive to maintain high measles-mumps-rubella (MMR) vaccination coverage
Missed Opportunities
Spatial Clustering of HIV Prevalence in Atlanta, Georgia and Population Characteristics Associated with Case Concentrations
Common values in assessing health outcomes from disease and injury
Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010
Disability-adjusted life years (Dalys) for 291 diseases and injuries in 21 regions, 1990–2010
Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010
A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010
Message Framing Strategies to Increase Influenza Immunization Uptake Among Pregnant African American Women
Global, regional, and national incidence and mortality for HIV, tuberculosis, and malaria during 1990–2013
Global, regional, and national levels and causes of maternal mortality during 1990–2013
Global, regional, and national levels of neonatal, infant, and under-5 mortality during 1990–2013
BACKGROUND: Remarkable financial and political efforts have been focused on the reduction of child mortality during the past few decades. Timely measurements of levels and trends in under-5 mortality are important to assess progress towards the Millennium Development Goal 4 (MDG 4) target of reduction of child mortality by two thirds from 1990 to 2015, and to identify models of success. METHODS: We generated updated estimates of child mortality i…
Vaccine hesitancy
Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks in 188 countries, 1990–2013
Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013
Comparison of impact and cost-effectiveness of rotavirus supplementary and routine immunization in a complex humanitarian emergency, Somali case study
Based on our model, rotavirus vaccination appears to be a cost-effective intervention as either RI or SIA, as defined by the World Health Organization as one to three times the per capita Gross Domestic Product (Somalia $112 in 2011). RI would have greater health impact and is more cost effective than SIA, assuming feasibility of reaching the target population. However, given the lack of infrastructure, whether RI is realistic in this setting rem…
Association Between Vaccine Refusal and Vaccine-Preventable Diseases in the United States
IMPORTANCE: Parents hesitant to vaccinate their children may delay routine immunizations or seek exemptions from state vaccine mandates. Recent outbreaks of vaccine-preventable diseases in the United States have drawn attention to this phenomenon. Improved understanding of the association between vaccine refusal and the epidemiology of these diseases is needed. OBJECTIVE: To review the published literature to evaluate the association between vacc…
Use of Fees to Discourage Nonmedical Exemptions to School Immunization Laws in US States
Recent outbreaks of vaccine-preventable diseases in the United States have renewed public discourse about state vaccine mandates for children entering schools. We review the use of taxes, fines, and fees as financial disincentives in public health. We argue that adding processing fees to a comprehensive set of administrative requirements for obtaining exemptions will avoid the use of taxpayer funding for exemption processing and will help tilt th…
Yogurt consumption during pregnancy and preterm delivery in M exican women
Preterm delivery is an important cause of perinatal morbidity and mortality, often precipitated by maternal infection or inflammation. Probiotic-containing foods, such as yogurt, may reduce systemic inflammatory responses. We sought to evaluate whether yogurt consumption during pregnancy is associated with decreased preterm delivery. We studied 965 women enrolled at midpregnancy into a clinical trial of prenatal docosahexaenoic acid supplementati…
Medicine (49 works) · Environmental health (38 works) · Vaccine Coverage and Hesitancy (29 works) · Public health (22 works) · Vaccination (21 works) · Demography (20 works) · Population (20 works) · Nursing (19 works) · Disease (18 works) · Family medicine (17 works)