Margot P Van De Weijer
Biographic Data
| ID | 1737409 |
|---|---|
| NAME | Margot P Van De Weijer |
| GIVEN NAMES | Margot P |
| FAMILY NAME | Van De Weijer |
| SIGNATURE | VAN DE WEIJER M P |
| AFFILIATIONS | Vrije Universiteit Amsterdam |
| ORCID | 0000-0001-9720-9481 |
| VERIFIED | Yes |
| TOTAL WORKS | 5 |
| TOTAL CITATIONS | 4 |
| AUTHOR COUNT | 5 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2022 |
| LATEST PUBLICATION YEAR | 2025 |
| H-INDEX | 1 |
Genetics of monozygotic twins reveals the impact of environmental sensitivity on psychiatric and neurodevelopmental phenotypes
Individual sensitivity to environmental exposures may be genetically influenced. This genotype-by-environment interplay implies differences in phenotypic variance across genotypes, but these variants have proven challenging to detect. Genome-wide association studies of monozygotic twin differences are conducted through family-based variance analyses, which are more robust to the systemic biases that impact population-based methods. We combined da…
Connecting the dots: Using a network approach to study the wellbeing spectrum
In positive psychology, defining the wellbeing construct has been a challenge. We used the psychometric network approach to study the structure of wellbeing. The sample consisted of Dutch adults registered with the Netherlands Twin Register. The variables were measured through standardized surveys. The network was estimated using the Mixed Graphical Models method and least absolute shrinkage and selection operator (LASSO) regularization to limit …
The Architecture of Happiness
Happiness is an increasingly prominent topic of interest across academia. However, relatively little attention has been paid to how it is created, especially not in a multidimensional sense. By ‘created’ we do not mean its influencing factors, for which there is extensive research, but how it actually forms in the person. The work that has been done in this arena tends to focus on physiological dynamics, which are certainly part of the puzzle. Bu…
A Re-evaluation of Candidate Gene Studies for Well-Being in Light of Genome-Wide Evidence
Ever since twin-family studies found that a substantial amount (± 40%) of the variation in well-being can be explained by genetic variation, several candidate genes have been proposed explaining this variation. However, these candidate gene and candidate gene-by-environment interaction studies have been surrounded by controversy regarding the validity and replication of their results. In the present study, we review the existing candidate gene li…
Self-rated health when population health is challenged by the Covid-19 pandemic; a longitudinal study
We theorize that the increases in SRH are explained by uninfected individuals evaluating their health more positively than under normal circumstances (partly through social comparison with infected individuals), rather than actual improvements. As the same genes are expressed under different environmental exposures, these results imply no evidence for gene-environment interaction. While different environmental factors might influence SRH at the t…
Self-rated health when population health is challenged by the Covid-19 pandemic; a longitudinal study
We theorize that the increases in SRH are explained by uninfected individuals evaluating their health more positively than under normal circumstances (partly through social comparison with infected individuals), rather than actual improvements. As the same genes are expressed under different environmental exposures, these results imply no evidence for gene-environment interaction. While different environmental factors might influence SRH at the t…
The Architecture of Happiness
Happiness is an increasingly prominent topic of interest across academia. However, relatively little attention has been paid to how it is created, especially not in a multidimensional sense. By ‘created’ we do not mean its influencing factors, for which there is extensive research, but how it actually forms in the person. The work that has been done in this arena tends to focus on physiological dynamics, which are certainly part of the puzzle. Bu…
A Re-evaluation of Candidate Gene Studies for Well-Being in Light of Genome-Wide Evidence
Ever since twin-family studies found that a substantial amount (± 40%) of the variation in well-being can be explained by genetic variation, several candidate genes have been proposed explaining this variation. However, these candidate gene and candidate gene-by-environment interaction studies have been surrounded by controversy regarding the validity and replication of their results. In the present study, we review the existing candidate gene li…
Self-rated health when population health is challenged by the Covid-19 pandemic; a longitudinal study
We theorize that the increases in SRH are explained by uninfected individuals evaluating their health more positively than under normal circumstances (partly through social comparison with infected individuals), rather than actual improvements. As the same genes are expressed under different environmental exposures, these results imply no evidence for gene-environment interaction. While different environmental factors might influence SRH at the t…
Connecting the dots: Using a network approach to study the wellbeing spectrum
In positive psychology, defining the wellbeing construct has been a challenge. We used the psychometric network approach to study the structure of wellbeing. The sample consisted of Dutch adults registered with the Netherlands Twin Register. The variables were measured through standardized surveys. The network was estimated using the Mixed Graphical Models method and least absolute shrinkage and selection operator (LASSO) regularization to limit …
Genetics of monozygotic twins reveals the impact of environmental sensitivity on psychiatric and neurodevelopmental phenotypes
Individual sensitivity to environmental exposures may be genetically influenced. This genotype-by-environment interplay implies differences in phenotypic variance across genotypes, but these variants have proven challenging to detect. Genome-wide association studies of monozygotic twin differences are conducted through family-based variance analyses, which are more robust to the systemic biases that impact population-based methods. We combined da…
Psychology (4 works) · Medicine (3 works) · Social Psychology (3 works) · Biology (2 works) · Cognitive Abilities and Testing (2 works) · Gene (2 works) · Genetic Associations and Epidemiology (2 works) · Genetics (2 works) · Psychological Well-being and Life Satisfaction (2 works) · Public health (2 works)