Marsha Michie
Biographic Data
| ID | 1738772 |
|---|---|
| NAME | Marsha Michie |
| GIVEN NAMES | Marsha |
| FAMILY NAME | Michie |
| SIGNATURE | MICHIE M |
| AFFILIATIONS | University of North Carolina at Chapel Hill |
| ORCID | 0000-0001-6631-828X |
| VERIFIED | Yes |
| TOTAL WORKS | 13 |
| TOTAL CITATIONS | 29 |
| AUTHOR COUNT | 12 |
| EDITOR COUNT | 1 |
| FIRST PUBLICATION YEAR | 2010 |
| LATEST PUBLICATION YEAR | 2026 |
| H-INDEX | 4 |
Trust As the Foundation for Informed Decision‐Making in Prenatal Genetic Screening and Diagnostic Testing
Rethinking the Burden of Traditional Informed Consent Prior to Prenatal Genetic Screening
The ethics literature and professional guidelines call for extensive discussions prior to prescreening consent to prenatal cell‐free DNA screening to, theoretically, allow patients to make decisions that match their values and goals of care. Most patients, however, actively avoid in‐depth moral deliberation when consenting to prenatal screening and then receive a screen‐negative result, suggesting that an information‐heavy process is irrelevant f…
Born Well
Born Well
Prioritizing Women's Health in Germline Editing Research
Although women are inextricably involved in the study of germline editing, their interests have not been significantly represented in debates about the evolution of genome editing technology. Discussions have taken place about effects of germline editing on women as parents and members of families, but key discussions about women's health and well-being as patients and subjects are lacking. This neglect is due in part to restrictions on uterine t…
Toward an Ethically Sensitive Implementation of Noninvasive Prenatal Screening in the Global Context
Noninvasive prenatal screening using cell‐free DNA, which analyzes placental DNA circulating in maternal blood to provide information about fetal chromosomal disorders early in pregnancy and without risk to the fetus, has been hailed as a potential “paradigm shift” in prenatal genetic screening. Commercial provision of cell‐free DNA screening has contributed to a rapid expansion of the tests included in the screening panels. The tests can include…
Informed decision-making about prenatal cfDNA screening
“I think we’ve got too many tests!”
Flexible positions, managed hopes
Research Participants' Perspectives on Genotype-Driven Research Recruitment
Genotype-driven recruitment is a potentially powerful approach for studying human genetic variation but presents ethical challenges. We conducted in-depth interviews with research participants in six studies where such recruitment occurred. Nearly all responded favorably to the acceptability of recontact for research recruitment, and genotype-driven recruitment was viewed as a positive sign of scientific advancement. Reactions to questions about …
If I Could in a Small Way Help”
Human genome research depends upon participants who donate genetic samples, but few studies have explored in depth the motivations of genetic research donors. This mixed methods study examines telephone interviews with 752 sample donors in a U.S. genetic epidemiology study investigating colorectal cancer. Quantitative and qualitative results indicate that most participants wanted to help society, and that many also wanted information about their …
The Meaning of Genetic Research Results
In the debate about whether to return individual genetic results to research participants, consideration of the nature of results has taken precedence over contextual factors associated with different study designs and populations. We conducted in-depth interviews with 24 individuals who participated in a genotype-driven study of cystic fibrosis: 9 of the individuals had cystic fibrosis, 15 had participated as healthy volunteers, and all had gene…
Narrating Disability, Narrating Religious Practice
This article examines the place of religion in the narratives of mothers of children with fragile X syndrome. In semistructured interviews, a majority of women combined narratives of religious practice with illness narratives, interpreting their children's disabilities within a religious framework. Informed by Arthur Frank's (1995) concept of “wounded storytellers,” the authors articulate a reconciliation narrative that mothers commonly used to d…
Flexible positions, managed hopes
Narrating Disability, Narrating Religious Practice
This article examines the place of religion in the narratives of mothers of children with fragile X syndrome. In semistructured interviews, a majority of women combined narratives of religious practice with illness narratives, interpreting their children's disabilities within a religious framework. Informed by Arthur Frank's (1995) concept of “wounded storytellers,” the authors articulate a reconciliation narrative that mothers commonly used to d…
If I Could in a Small Way Help”
Human genome research depends upon participants who donate genetic samples, but few studies have explored in depth the motivations of genetic research donors. This mixed methods study examines telephone interviews with 752 sample donors in a U.S. genetic epidemiology study investigating colorectal cancer. Quantitative and qualitative results indicate that most participants wanted to help society, and that many also wanted information about their …
The Meaning of Genetic Research Results
In the debate about whether to return individual genetic results to research participants, consideration of the nature of results has taken precedence over contextual factors associated with different study designs and populations. We conducted in-depth interviews with 24 individuals who participated in a genotype-driven study of cystic fibrosis: 9 of the individuals had cystic fibrosis, 15 had participated as healthy volunteers, and all had gene…
Research Participants' Perspectives on Genotype-Driven Research Recruitment
Genotype-driven recruitment is a potentially powerful approach for studying human genetic variation but presents ethical challenges. We conducted in-depth interviews with research participants in six studies where such recruitment occurred. Nearly all responded favorably to the acceptability of recontact for research recruitment, and genotype-driven recruitment was viewed as a positive sign of scientific advancement. Reactions to questions about …
Narrating Disability, Narrating Religious Practice
This article examines the place of religion in the narratives of mothers of children with fragile X syndrome. In semistructured interviews, a majority of women combined narratives of religious practice with illness narratives, interpreting their children's disabilities within a religious framework. Informed by Arthur Frank's (1995) concept of “wounded storytellers,” the authors articulate a reconciliation narrative that mothers commonly used to d…
Research Participants' Perspectives on Genotype-Driven Research Recruitment
Genotype-driven recruitment is a potentially powerful approach for studying human genetic variation but presents ethical challenges. We conducted in-depth interviews with research participants in six studies where such recruitment occurred. Nearly all responded favorably to the acceptability of recontact for research recruitment, and genotype-driven recruitment was viewed as a positive sign of scientific advancement. Reactions to questions about …
If I Could in a Small Way Help”
Human genome research depends upon participants who donate genetic samples, but few studies have explored in depth the motivations of genetic research donors. This mixed methods study examines telephone interviews with 752 sample donors in a U.S. genetic epidemiology study investigating colorectal cancer. Quantitative and qualitative results indicate that most participants wanted to help society, and that many also wanted information about their …
The Meaning of Genetic Research Results
In the debate about whether to return individual genetic results to research participants, consideration of the nature of results has taken precedence over contextual factors associated with different study designs and populations. We conducted in-depth interviews with 24 individuals who participated in a genotype-driven study of cystic fibrosis: 9 of the individuals had cystic fibrosis, 15 had participated as healthy volunteers, and all had gene…
Flexible positions, managed hopes
Informed decision-making about prenatal cfDNA screening
“I think we’ve got too many tests!”
Toward an Ethically Sensitive Implementation of Noninvasive Prenatal Screening in the Global Context
Noninvasive prenatal screening using cell‐free DNA, which analyzes placental DNA circulating in maternal blood to provide information about fetal chromosomal disorders early in pregnancy and without risk to the fetus, has been hailed as a potential “paradigm shift” in prenatal genetic screening. Commercial provision of cell‐free DNA screening has contributed to a rapid expansion of the tests included in the screening panels. The tests can include…
Prioritizing Women's Health in Germline Editing Research
Although women are inextricably involved in the study of germline editing, their interests have not been significantly represented in debates about the evolution of genome editing technology. Discussions have taken place about effects of germline editing on women as parents and members of families, but key discussions about women's health and well-being as patients and subjects are lacking. This neglect is due in part to restrictions on uterine t…
Born Well
Born Well
Rethinking the Burden of Traditional Informed Consent Prior to Prenatal Genetic Screening
The ethics literature and professional guidelines call for extensive discussions prior to prescreening consent to prenatal cell‐free DNA screening to, theoretically, allow patients to make decisions that match their values and goals of care. Most patients, however, actively avoid in‐depth moral deliberation when consenting to prenatal screening and then receive a screen‐negative result, suggesting that an information‐heavy process is irrelevant f…
Trust As the Foundation for Informed Decision‐Making in Prenatal Genetic Screening and Diagnostic Testing
Psychology (9 works) · Biology (6 works) · BRCA gene mutations in cancer (6 works) · Genetics (5 works) · Medicine (5 works) · Prenatal Screening and Diagnostics (5 works) · Family medicine (4 works) · Political science (4 works) · Social Psychology (4 works) · Social Psychology (4 works)