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Frank Joseph Palella

Biographic Data

ID1741649
NAMEFrank Joseph Palella
GIVEN NAMESFrank Joseph
FAMILY NAMEPalella
SIGNATUREPALELLA F J
AFFILIATIONSNorthwestern University
ORCID0000-0002-2277-6841
VERIFIEDYes
TOTAL WORKS14
TOTAL CITATIONS4
AUTHOR COUNT14
EDITOR COUNT0
FIRST PUBLICATION YEAR1998
LATEST PUBLICATION YEAR2025
H-INDEX1
  • Does Resilience Mediate the Relationship Between Negative Self-Image and Psychological Distress in Middle-Aged and Older Gay and Bisexual Men

    Open Access•Mark Brennan‐ing, Sabina Haberlen et al.•ARTICLE•Research on Aging•2025

    Aging gay and bisexual men may have negative self-image s due to body image dissatisfaction and internalized ageism, resulting in psychological distress. Gay and bisexual men with HIV may be at greater risk for distress because of research linking HIV to accelerated aging. We examined associations between self-image and psychological distress, and potential mediating effects ( resilience, fitness engagement ) , and whether these relationships wer…

  • Psychosocial, Behavioral, and HIV-Related Health Among Men Living with HIV Who Have a History of Incarceration

    Open Access•Chloe J Kaminsky, Emily M Cherenack et al.•ARTICLE•AIDS and Behavior•2025

    Incarceration is intricately linked with the HIV epidemic, with incarcerated individuals exhibiting HIV prevalence rates three times higher than the general population. We used baseline data from the Multicenter AIDS Cohort Study (MACS)/Women's Interagency HIV Study (WIHS) Combined Cohort Study (MWCCS) to describe select health outcomes among men living with HIV (MWH) who have never been incarcerated and with a history of lifetime incarceration, …

  • Physical Activity, Cigarette Smoking, and Depression Among People with HIV

    Open Access•Nicholas J Santabarbara, Melissa A St Hilaire et al.•ARTICLE•AIDS and Behavior•2025

  • Incidence of erectile dysfunction among middle-aged and aging sexual minority men living with or without HIV

    Open Access•Aishat Mustapha, Brittanny M Polanka et al.•ARTICLE•Frontiers in Public Health•2024

    Introduction: Erectile dysfunction (ED) has been established as a comorbidity among men living with HIV, but comparisons by HIV serostatus of ED incidence in a longitudinal follow-up cohort of men are lacking. We sought to evaluate the incidence of ED spanning a period of 12 years in a longitudinal cohort of sexual minority men (SMM) living with and without HIV. Methods: We analyzed ED incidence data for 625 participants in the longitudinal Multi…

  • Longitudinal Analysis of Overlapping Psychosocial Factors Predicting Incident Hospitalization Among Mixed HIV Serostatus Men who have Sex with Men in the Multicenter Aids Cohort Study

    Open Access•Yuhang Qian, Roger Detels et al.•ARTICLE•AIDS and Behavior•2024

  • Effects of Erectile Dysfunction Drugs Use on T-Cells and Immune Markers on Men Who Have Sex with Men

    Jee Won Park, Onyebuchi A Arah et al.•ARTICLE•International Journal of Sexual…•2022

    Objective: Examine prospective relationships between erectile dysfunction (ED) drugs EDand CD4 and CD8 T-cells, and immune markers among men who have sex with men (MSM). Methods: Data from Multicenter AIDS Cohort Study, an observational prospective cohort study, with semi-annual follow-ups conducted in four U.S. centers from 1998 onwards was used. Marginal structural models using g-computation was fitted to estimate the mean differences for the e…

  • Longitudinal Changes in, and Factors Associated with, the Frequency of Condomless Sex Among People in Care for HIV Infection, HIV Outpatient Study USA, 2007–2019

    Open Access•Marcus D Durham, Carl Armon et al.•ARTICLE•AIDS and Behavior•2022

  • Psychometric assessment of a homophobia management scale among cisgender sexual minority men in midlife and older adulthood

    Open Access•Steven Meanley, Mark Brennan‐ing et al.•ARTICLE•Psychology of Sexual Orientation…•2022•References: 11

    Interpersonal management of homophobic stigma (e.g., selectively constructing one's social network; confronting stigma) is an understudied area of resilience among sexual minority people. Among a sample of cisgender sexual minority men (SMM; N = 798) in midlife and older adulthood, we assessed the psychometric properties and characterized the sociodemographic differences of our newly developed, theory-informed homophobia management scale. Data co…

  • Psychological Connection to the Gay Community and Negative Self-Appraisals in Middle-Aged and Older Men Who Have Sex With Men: The Mediating Effects of Fitness Engagement

    Open Access•Mark Brennan-Ing, Mark Brennan‐ing et al.•ARTICLE•The Journals of Gerontology…•2021•Cited by: 3•References: 8

    Connection to the gay community may be a source of resilience for aging MSM by lessening negative self-appraisals and promoting strategies that address body image dissatisfaction and self-perceptions of aging. Interventions facilitating connections to the gay community may support healthy aging in this population

  • Characteristics and Longitudinal Patterns of Erectile Dysfunction Drug Use Among Men Who Have Sex with Men in the U.S

    Open Access•Jee Won Park, Adrian S Dobs et al.•ARTICLE•Archives of Sexual Behavior•2021•References: 33

    We investigated the longitudinal relationship between erectile dysfunction (ED) drug use with behavioral factors, including substance use and sexual activities in men who have sex with men from the Multicenter AIDS Cohort Study during 1998–2016 ( n = 1636). We used a bivariate random-intercept model to evaluate ED drug use along with other behavioral factors to assess relationships between the two outcomes over time on a population level and also…

  • Social-environmental resiliencies protect against loneliness among HIV-Positive and HIV- negative older men who have sex with men: Results from the Multicenter Aids Cohort Study (Macs)

    Open Access•Maria De Jesus, David Ware et al.•ARTICLE•Social Science & Medicine•2021•Cited by: 1•References: 48

  • Influence of gender on receipt of guideline-based antiretroviral therapy in the era of Haart

    Jennifer Cocohoba, Jennifer M Cocohoba et al.•ARTICLE•AIDS Care•2012

    United States HIV guidelines delineate preferred antiretroviral treatment (ART) and discourage use of sub-potent, toxic, or adversely interacting combinations. It is unclear how often patients receive guideline concordant ART and what factors are correlated with receiving guideline-inconsistent ART. The objective of this study was to assess ART reported by participants of the Women's Interagency HIV Study (WIHS) and the Multicenter AIDS Cohort St…

  • Mortality in the Highly Active Antiretroviral Therapy Era: Changing Causes of Death and Disease in the HIV Outpatient Study

    Frank Joseph Palella, Rose Baker et al.•ARTICLE•JAIDS Journal of Acquired Immune…•2006

    BACKGROUND: AIDS-related death and disease rates have declined in the highly active antiretroviral therapy (HAART) era and remain low; however, current causes of death in HAART-treated patients remain ill defined. OBJECTIVE: To describe mortality trends and causes of death among HIV-infected patients in the HAART era. DESIGN: Prospective, multicenter, observational cohort study of participants in the HIV Outpatient Study who were treated from Jan…

  • Declining Morbidity and Mortality among Patients with Advanced Human Immunodeficiency Virus Infection

    Frank Joseph Palella, Kathleen M Delaney et al.•ARTICLE•New England Journal of Medicine•1998

    BACKGROUND AND METHODS: National surveillance data show recent, marked reductions in morbidity and mortality associated with the acquired immunodeficiency syndrome (AIDS). To evaluate these declines, we analyzed data on 1255 patients, each of whom had at least one CD4+ count below 100 cells per cubic millimeter, who were seen at nine clinics specializing in the treatment of human immunodeficiency virus (HIV) infection in eight U.S. cities from Ja…

  • Psychological Connection to the Gay Community and Negative Self-Appraisals in Middle-Aged and Older Men Who Have Sex With Men: The Mediating Effects of Fitness Engagement

    Open Access•Mark Brennan-Ing, Mark Brennan‐ing et al.•ARTICLE•The Journals of Gerontology…•2021•Cited by: 3•References: 8

    Connection to the gay community may be a source of resilience for aging MSM by lessening negative self-appraisals and promoting strategies that address body image dissatisfaction and self-perceptions of aging. Interventions facilitating connections to the gay community may support healthy aging in this population

  • Social-environmental resiliencies protect against loneliness among HIV-Positive and HIV- negative older men who have sex with men: Results from the Multicenter Aids Cohort Study (Macs)

    Open Access•Maria De Jesus, David Ware et al.•ARTICLE•Social Science & Medicine•2021•Cited by: 1•References: 48

  • Declining Morbidity and Mortality among Patients with Advanced Human Immunodeficiency Virus Infection

    Frank Joseph Palella, Kathleen M Delaney et al.•ARTICLE•New England Journal of Medicine•1998

    BACKGROUND AND METHODS: National surveillance data show recent, marked reductions in morbidity and mortality associated with the acquired immunodeficiency syndrome (AIDS). To evaluate these declines, we analyzed data on 1255 patients, each of whom had at least one CD4+ count below 100 cells per cubic millimeter, who were seen at nine clinics specializing in the treatment of human immunodeficiency virus (HIV) infection in eight U.S. cities from Ja…

  • Mortality in the Highly Active Antiretroviral Therapy Era: Changing Causes of Death and Disease in the HIV Outpatient Study

    Frank Joseph Palella, Rose Baker et al.•ARTICLE•JAIDS Journal of Acquired Immune…•2006

    BACKGROUND: AIDS-related death and disease rates have declined in the highly active antiretroviral therapy (HAART) era and remain low; however, current causes of death in HAART-treated patients remain ill defined. OBJECTIVE: To describe mortality trends and causes of death among HIV-infected patients in the HAART era. DESIGN: Prospective, multicenter, observational cohort study of participants in the HIV Outpatient Study who were treated from Jan…

  • Influence of gender on receipt of guideline-based antiretroviral therapy in the era of Haart

    Jennifer Cocohoba, Jennifer M Cocohoba et al.•ARTICLE•AIDS Care•2012

    United States HIV guidelines delineate preferred antiretroviral treatment (ART) and discourage use of sub-potent, toxic, or adversely interacting combinations. It is unclear how often patients receive guideline concordant ART and what factors are correlated with receiving guideline-inconsistent ART. The objective of this study was to assess ART reported by participants of the Women's Interagency HIV Study (WIHS) and the Multicenter AIDS Cohort St…

  • Psychological Connection to the Gay Community and Negative Self-Appraisals in Middle-Aged and Older Men Who Have Sex With Men: The Mediating Effects of Fitness Engagement

    Open Access•Mark Brennan-Ing, Mark Brennan‐ing et al.•ARTICLE•The Journals of Gerontology…•2021•Cited by: 3•References: 8

    Connection to the gay community may be a source of resilience for aging MSM by lessening negative self-appraisals and promoting strategies that address body image dissatisfaction and self-perceptions of aging. Interventions facilitating connections to the gay community may support healthy aging in this population

  • Characteristics and Longitudinal Patterns of Erectile Dysfunction Drug Use Among Men Who Have Sex with Men in the U.S

    Open Access•Jee Won Park, Adrian S Dobs et al.•ARTICLE•Archives of Sexual Behavior•2021•References: 33

    We investigated the longitudinal relationship between erectile dysfunction (ED) drug use with behavioral factors, including substance use and sexual activities in men who have sex with men from the Multicenter AIDS Cohort Study during 1998–2016 ( n = 1636). We used a bivariate random-intercept model to evaluate ED drug use along with other behavioral factors to assess relationships between the two outcomes over time on a population level and also…

  • Social-environmental resiliencies protect against loneliness among HIV-Positive and HIV- negative older men who have sex with men: Results from the Multicenter Aids Cohort Study (Macs)

    Open Access•Maria De Jesus, David Ware et al.•ARTICLE•Social Science & Medicine•2021•Cited by: 1•References: 48

  • Effects of Erectile Dysfunction Drugs Use on T-Cells and Immune Markers on Men Who Have Sex with Men

    Jee Won Park, Onyebuchi A Arah et al.•ARTICLE•International Journal of Sexual…•2022

    Objective: Examine prospective relationships between erectile dysfunction (ED) drugs EDand CD4 and CD8 T-cells, and immune markers among men who have sex with men (MSM). Methods: Data from Multicenter AIDS Cohort Study, an observational prospective cohort study, with semi-annual follow-ups conducted in four U.S. centers from 1998 onwards was used. Marginal structural models using g-computation was fitted to estimate the mean differences for the e…

  • Longitudinal Changes in, and Factors Associated with, the Frequency of Condomless Sex Among People in Care for HIV Infection, HIV Outpatient Study USA, 2007–2019

    Open Access•Marcus D Durham, Carl Armon et al.•ARTICLE•AIDS and Behavior•2022

  • Psychometric assessment of a homophobia management scale among cisgender sexual minority men in midlife and older adulthood

    Open Access•Steven Meanley, Mark Brennan‐ing et al.•ARTICLE•Psychology of Sexual Orientation…•2022•References: 11

    Interpersonal management of homophobic stigma (e.g., selectively constructing one's social network; confronting stigma) is an understudied area of resilience among sexual minority people. Among a sample of cisgender sexual minority men (SMM; N = 798) in midlife and older adulthood, we assessed the psychometric properties and characterized the sociodemographic differences of our newly developed, theory-informed homophobia management scale. Data co…

  • Incidence of erectile dysfunction among middle-aged and aging sexual minority men living with or without HIV

    Open Access•Aishat Mustapha, Brittanny M Polanka et al.•ARTICLE•Frontiers in Public Health•2024

    Introduction: Erectile dysfunction (ED) has been established as a comorbidity among men living with HIV, but comparisons by HIV serostatus of ED incidence in a longitudinal follow-up cohort of men are lacking. We sought to evaluate the incidence of ED spanning a period of 12 years in a longitudinal cohort of sexual minority men (SMM) living with and without HIV. Methods: We analyzed ED incidence data for 625 participants in the longitudinal Multi…

  • Longitudinal Analysis of Overlapping Psychosocial Factors Predicting Incident Hospitalization Among Mixed HIV Serostatus Men who have Sex with Men in the Multicenter Aids Cohort Study

    Open Access•Yuhang Qian, Roger Detels et al.•ARTICLE•AIDS and Behavior•2024

  • Does Resilience Mediate the Relationship Between Negative Self-Image and Psychological Distress in Middle-Aged and Older Gay and Bisexual Men

    Open Access•Mark Brennan‐ing, Sabina Haberlen et al.•ARTICLE•Research on Aging•2025

    Aging gay and bisexual men may have negative self-image s due to body image dissatisfaction and internalized ageism, resulting in psychological distress. Gay and bisexual men with HIV may be at greater risk for distress because of research linking HIV to accelerated aging. We examined associations between self-image and psychological distress, and potential mediating effects ( resilience, fitness engagement ) , and whether these relationships wer…

  • Psychosocial, Behavioral, and HIV-Related Health Among Men Living with HIV Who Have a History of Incarceration

    Open Access•Chloe J Kaminsky, Emily M Cherenack et al.•ARTICLE•AIDS and Behavior•2025

    Incarceration is intricately linked with the HIV epidemic, with incarcerated individuals exhibiting HIV prevalence rates three times higher than the general population. We used baseline data from the Multicenter AIDS Cohort Study (MACS)/Women's Interagency HIV Study (WIHS) Combined Cohort Study (MWCCS) to describe select health outcomes among men living with HIV (MWH) who have never been incarcerated and with a history of lifetime incarceration, …

  • Physical Activity, Cigarette Smoking, and Depression Among People with HIV

    Open Access•Nicholas J Santabarbara, Melissa A St Hilaire et al.•ARTICLE•AIDS and Behavior•2025

HIV/AIDS Research and Interventions (13 works) · Medicine (12 works) · Internal Medicine (8 works) · Human immunodeficiency virus (HIV (7 works) · Cohort study (6 works) · Men who have sex with men (6 works) · Psychology (6 works) · Viral load (6 works) · Cohort (5 works) · Gerontology (5 works)

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