Jacqueline Ndirangu
Dados Biográficos
| ID | 1742207 |
|---|---|
| NOME | Jacqueline Ndirangu |
| PRENOMES | Jacqueline |
| SOBRENOME | Ndirangu |
| ASSINATURA | NDIRANGU J |
| AFILIAÇÕES | RTI International |
| ORCID | 0000-0001-8346-7359 |
| VERIFICADO | Sim |
| TOTAL DE OBRAS | 16 |
| TOTAL DE CITAÇÕES | 2 |
| TOTAL COMO AUTOR | 16 |
| TOTAL COMO EDITOR | 0 |
| PRIMEIRO ANO DE PUBLICAÇÃO | 2014 |
| ANO MAIS RECENTE DE PUBLICAÇÃO | 2026 |
| ÍNDICE H | 1 |
Relationship Power, Partner Risk Characteristics, and Recent Intimate Partner Violence Among Adolescent Girls and Young Women in a High HIV Incidence Setting in Kenya
Adolescent girls and young women (AGYW) in sub-Saharan Africa face intersecting risks of HIV and intimate partner violence (IPV). Although pre-exposure prophylaxis (PrEP) expands HIV prevention options, its use is often constrained by imbalanced relationship power and male partner behaviors. We used baseline data from the Tu’Washindi na PrEP cluster randomized trial to describe PrEP use, relationship dynamics and identify attributes associated wi…
Outcomes of substance use and sexual power among adolescent girls and young women in Cape Town
Adolescent girls and young women (AGYW) in South Africa experience contextual barriers to HIV risk reduction including incomplete schooling, unintended pregnancy, substance use, and gender-based violence. A cluster randomised trial in Cape Town allocated 24 Black and Coloured communities to a gender-focused HIV risk-reduction intervention or HIV testing, with 500 AGYW total enrolled. We evaluated intervention efficacy by comparing mean difference…
Relationship Between Criminal and Status Offense Behaviors, Substance Use, and HIV Risk Among Adolescent Girls and Young Women in Cape Town, South Africa
This study aimed to examine the relationship between externalizing behaviors, substance use, and sexual risk among adolescent girls and young women (AGYW) in Cape Town, South Africa, who experience social disadvantage characterized by poverty and school dropout. We analyzed baseline data from 500 AGYW in a cluster-randomized trial who had dropped out of school. Multivariate logistic regression models explored associations between self-reported cr…
The Importance of the Individual in PrEP Uptake
‘We have goals but [it is difficult]’. Barriers to antiretroviral therapy adherence among women using alcohol and other drugs living with HIV in South Africa
BACKGROUND: Women living with HIV who misuse alcohol and live in economically disadvantaged settings in South Africa experience a multitude of contextual barriers as they navigate the HIV care continuum. The Women's Health CoOp (WHC), a brief, woman-focused, behavioural, evidence-based intervention, has been shown to be effective in reducing heavy drinking and improving HIV-related outcomes among this key population. However, these women face oth…
Stigma in the health clinic and implications for PrEP access and use by adolescent girls and young women
Evidence is needed to inform strategies for addressing clinic stigma toward AGYW, with the goal of removing barriers to PrEP services for this group. While awareness has increased and progress has been achieved around the provision of comprehensive, youth-friendly sexual and reproductive health services, these programs need to be adapted for the specific concerns of young people seeking PrEP services. Our findings point to the four key areas note…
Social Determinants of Alcohol and Other Drug Misuse Among Women Living with HIV in Economically Underserved Communities in Cape Town, South Africa
Sustainability of a gender-focused HIV and alcohol risk-reduction intervention in usual care settings in South Africa
Intervention sustainability is a critical yet understudied aspect of implementation science research. To address this gap, we examined the sustainability of the Women’s Health CoOp (WHC), a gender-focused, evidence-based, HIV and alcohol risk-reduction intervention, after an implementation trial. We used a mixed methods design consisting of questionnaires (n = 12), 3 focus groups (n = 11), and a semistructured interview conducted with interventio…
Antiretroviral Therapy (ART) Adherence and Prenatal Alcohol Use among Women Who Are Pregnant with HIV in South Africa
This brief report emphasizes the need to focus on women with HIV who are pregnant who use alcohol or other drugs. A recently completed implementation science study tested a gender-focused behavioral intervention, the Women's Health CoOp (WHC), to improve antiretroviral therapy (ART) adherence and reduce alcohol use among women with HIV. The study identified 33 participants who had a positive pregnancy test result at the baseline assessment, of wh…
Outcomes of Implementing in the Real World the Women's Health CoOp Intervention in Cape Town, South Africa
Women in South Africa living with HIV who use alcohol may not adhere to ART, affecting the country's 90-90-90 targets. The Women's Health CoOp (WHC), a woman-focused HIV intervention, has shown efficacy in numerous trials with key populations of women in South Africa who use alcohol and drugs. In a hybrid implementation effectiveness study, the WHC was implemented in usual care clinics by healthcare providers in a modified stepped-wedge design. W…
The PrEpare Pretoria Project
Background Despite increased prevention efforts, HIV remains the leading cause of death among adolescent girls and young women in South Africa. Although research indicates important determinants of HIV acquisition at the individual and interpersonal levels, structural-level stigma and discrimination continue to be critical barriers to reaching and retaining this key population for HIV prevention and sexual and reproductive health services. Innova…
Exploring the associations between physical and sexual gender-based violence and HIV among women who use substances in South Africa
Objective: South Africa has the highest prevalence of HIV among women, the highest prevalence of gender-based violence (GBV), and the highest rates of per capita alcohol consumption in the world. The nuanced associations between GBV, alcohol misuse, and HIV must be explored and protective factors identified. This study examines the associations between physical and sexual GBV and HIV infection and explores how alcohol misuse and sexual agency may…
The Young Women’s Health CoOp in Cape Town, South Africa
Trial registration no: NCT02974998 , November 29, 2016
Changing sex risk behaviors, gender norms, and relationship dynamics among couples in Cape Town, South Africa
HIV Prevention Among Women Who Use Substances And Report Sex Work
The biobehavioral Women’s Health CoOp in Pretoria, South Africa
Trial registration no: NCT01497405
The biobehavioral Women’s Health CoOp in Pretoria, South Africa
Trial registration no: NCT01497405
HIV Prevention Among Women Who Use Substances And Report Sex Work
The Young Women’s Health CoOp in Cape Town, South Africa
Trial registration no: NCT02974998 , November 29, 2016
Changing sex risk behaviors, gender norms, and relationship dynamics among couples in Cape Town, South Africa
Exploring the associations between physical and sexual gender-based violence and HIV among women who use substances in South Africa
Objective: South Africa has the highest prevalence of HIV among women, the highest prevalence of gender-based violence (GBV), and the highest rates of per capita alcohol consumption in the world. The nuanced associations between GBV, alcohol misuse, and HIV must be explored and protective factors identified. This study examines the associations between physical and sexual GBV and HIV infection and explores how alcohol misuse and sexual agency may…
The PrEpare Pretoria Project
Background Despite increased prevention efforts, HIV remains the leading cause of death among adolescent girls and young women in South Africa. Although research indicates important determinants of HIV acquisition at the individual and interpersonal levels, structural-level stigma and discrimination continue to be critical barriers to reaching and retaining this key population for HIV prevention and sexual and reproductive health services. Innova…
Sustainability of a gender-focused HIV and alcohol risk-reduction intervention in usual care settings in South Africa
Intervention sustainability is a critical yet understudied aspect of implementation science research. To address this gap, we examined the sustainability of the Women’s Health CoOp (WHC), a gender-focused, evidence-based, HIV and alcohol risk-reduction intervention, after an implementation trial. We used a mixed methods design consisting of questionnaires (n = 12), 3 focus groups (n = 11), and a semistructured interview conducted with interventio…
Antiretroviral Therapy (ART) Adherence and Prenatal Alcohol Use among Women Who Are Pregnant with HIV in South Africa
This brief report emphasizes the need to focus on women with HIV who are pregnant who use alcohol or other drugs. A recently completed implementation science study tested a gender-focused behavioral intervention, the Women's Health CoOp (WHC), to improve antiretroviral therapy (ART) adherence and reduce alcohol use among women with HIV. The study identified 33 participants who had a positive pregnancy test result at the baseline assessment, of wh…
Outcomes of Implementing in the Real World the Women's Health CoOp Intervention in Cape Town, South Africa
Women in South Africa living with HIV who use alcohol may not adhere to ART, affecting the country's 90-90-90 targets. The Women's Health CoOp (WHC), a woman-focused HIV intervention, has shown efficacy in numerous trials with key populations of women in South Africa who use alcohol and drugs. In a hybrid implementation effectiveness study, the WHC was implemented in usual care clinics by healthcare providers in a modified stepped-wedge design. W…
‘We have goals but [it is difficult]’. Barriers to antiretroviral therapy adherence among women using alcohol and other drugs living with HIV in South Africa
BACKGROUND: Women living with HIV who misuse alcohol and live in economically disadvantaged settings in South Africa experience a multitude of contextual barriers as they navigate the HIV care continuum. The Women's Health CoOp (WHC), a brief, woman-focused, behavioural, evidence-based intervention, has been shown to be effective in reducing heavy drinking and improving HIV-related outcomes among this key population. However, these women face oth…
Stigma in the health clinic and implications for PrEP access and use by adolescent girls and young women
Evidence is needed to inform strategies for addressing clinic stigma toward AGYW, with the goal of removing barriers to PrEP services for this group. While awareness has increased and progress has been achieved around the provision of comprehensive, youth-friendly sexual and reproductive health services, these programs need to be adapted for the specific concerns of young people seeking PrEP services. Our findings point to the four key areas note…
Social Determinants of Alcohol and Other Drug Misuse Among Women Living with HIV in Economically Underserved Communities in Cape Town, South Africa
Relationship Between Criminal and Status Offense Behaviors, Substance Use, and HIV Risk Among Adolescent Girls and Young Women in Cape Town, South Africa
This study aimed to examine the relationship between externalizing behaviors, substance use, and sexual risk among adolescent girls and young women (AGYW) in Cape Town, South Africa, who experience social disadvantage characterized by poverty and school dropout. We analyzed baseline data from 500 AGYW in a cluster-randomized trial who had dropped out of school. Multivariate logistic regression models explored associations between self-reported cr…
The Importance of the Individual in PrEP Uptake
Outcomes of substance use and sexual power among adolescent girls and young women in Cape Town
Adolescent girls and young women (AGYW) in South Africa experience contextual barriers to HIV risk reduction including incomplete schooling, unintended pregnancy, substance use, and gender-based violence. A cluster randomised trial in Cape Town allocated 24 Black and Coloured communities to a gender-focused HIV risk-reduction intervention or HIV testing, with 500 AGYW total enrolled. We evaluated intervention efficacy by comparing mean difference…
Relationship Power, Partner Risk Characteristics, and Recent Intimate Partner Violence Among Adolescent Girls and Young Women in a High HIV Incidence Setting in Kenya
Adolescent girls and young women (AGYW) in sub-Saharan Africa face intersecting risks of HIV and intimate partner violence (IPV). Although pre-exposure prophylaxis (PrEP) expands HIV prevention options, its use is often constrained by imbalanced relationship power and male partner behaviors. We used baseline data from the Tu’Washindi na PrEP cluster randomized trial to describe PrEP use, relationship dynamics and identify attributes associated wi…
Medicine (14 obras) · Adolescent Sexual and Reproductive Health (13 obras) · Environmental health (11 obras) · HIV/AIDS Research and Interventions (11 obras) · Family medicine (10 obras) · Public health (9 obras) · Human immunodeficiency virus (HIV (8 obras) · Nursing (8 obras) · Psychology (7 obras) · Demography (6 obras)