Caleb E Finch
Biographic Data
| ID | 182669 |
|---|---|
| NAME | Caleb E Finch |
| GIVEN NAMES | Caleb E |
| FAMILY NAME | Finch |
| SIGNATURE | FINCH C E |
| AFFILIATIONS | University of Southern California |
| ORCID | 0000-0002-7617-3958 |
| VERIFIED | Yes |
| TOTAL WORKS | 10 |
| TOTAL CITATIONS | 3 |
| WORKS AS AUTHOR | 10 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 1970 |
| LATEST PUBLICATION YEAR | 2026 |
| H-INDEX | 1 |
Exceptionally low mortality despite widespread Covid-19 infection among Indigenous Tsimane and Moseten of Bolivia
Inflammatory Gene Variants in the Tsimane, an Indigenous Bolivian Population with a High Infectious Load
The Tsimane of lowland Bolivia are an indigenous forager-farmer population living under conditions resembling pre-industrial European populations, with high infectious morbidity, high infection and inflammation, and shortened life expectancy. Analysis of 917 persons ages 5 to 60+ showed that allele frequencies of 9 SNPs examined in the apolipoprotein E (apoE), C-reactive protein (CRP), and interleukin-6 (IL-6) genes differed from some European, A…
Blood lipids, infection, and inflammatory markers in the Tsimane of Bolivia
Objectives: Little is known about blood cholesterol (blood‐C) levels under conditions of infection and limited diet. This study examines blood‐C and markers of infection and inflammation in the Tsimane of the Bolivian Amazon, indigenous forager farmers living in conditions that model preindustrial European populations by their short life expectancy, high load of infections and inflammation, and limited diets. Methods: We use multivariate models t…
The rise and fall of excess male infant mortality
The male disadvantage in infant mortality underwent a surprising rise and fall in the 20th century. Our analysis of 15 developed countries shows that, as infant mortality declined over two centuries, the excess male mortality increased from 10% in 1751 to >30% by approximately 1970. Remarkably, since 1970, the male disadvantage in most countries fell back to lower levels. The worsening male disadvantage from 1751 until 1970 may be due to differen…
Infection, inflammation, height, and longevity
Using historical data from cohorts born before the 20th century in four northern European countries, we show that increasing longevity and declining mortality in the elderly occurred among the same birth cohorts that experienced a reduction in mortality at younger ages. Concurrently, these cohorts also experienced increasing adult height. We hypothesize that both the decline in old-age mortality and the increase in height were promoted by the red…
Aging, Inflammation & the Body Electric
Inflammatory Exposure and Historical Changes in Human Life-Spans
Most explanations of the increase in life expectancy at older ages over history emphasize the importance of medical and public health factors of a particular historical period. We propose that the reduction in lifetime exposure to infectious diseases and other sources of inflammation—a cohort mechanism—has also made an important contribution to the historical decline in old-age mortality. Analysis of birth cohorts across the life-span since 1751 …
On the Biodemography of Aging
High, usual and impaired functioning in community-dwelling older men and women
Bluegrass from the Blue Ridge
Inflammatory Gene Variants in the Tsimane, an Indigenous Bolivian Population with a High Infectious Load
The Tsimane of lowland Bolivia are an indigenous forager-farmer population living under conditions resembling pre-industrial European populations, with high infectious morbidity, high infection and inflammation, and shortened life expectancy. Analysis of 917 persons ages 5 to 60+ showed that allele frequencies of 9 SNPs examined in the apolipoprotein E (apoE), C-reactive protein (CRP), and interleukin-6 (IL-6) genes differed from some European, A…
Bluegrass from the Blue Ridge
High, usual and impaired functioning in community-dwelling older men and women
On the Biodemography of Aging
Inflammatory Exposure and Historical Changes in Human Life-Spans
Most explanations of the increase in life expectancy at older ages over history emphasize the importance of medical and public health factors of a particular historical period. We propose that the reduction in lifetime exposure to infectious diseases and other sources of inflammation—a cohort mechanism—has also made an important contribution to the historical decline in old-age mortality. Analysis of birth cohorts across the life-span since 1751 …
Infection, inflammation, height, and longevity
Using historical data from cohorts born before the 20th century in four northern European countries, we show that increasing longevity and declining mortality in the elderly occurred among the same birth cohorts that experienced a reduction in mortality at younger ages. Concurrently, these cohorts also experienced increasing adult height. We hypothesize that both the decline in old-age mortality and the increase in height were promoted by the red…
Aging, Inflammation & the Body Electric
The rise and fall of excess male infant mortality
The male disadvantage in infant mortality underwent a surprising rise and fall in the 20th century. Our analysis of 15 developed countries shows that, as infant mortality declined over two centuries, the excess male mortality increased from 10% in 1751 to >30% by approximately 1970. Remarkably, since 1970, the male disadvantage in most countries fell back to lower levels. The worsening male disadvantage from 1751 until 1970 may be due to differen…
Blood lipids, infection, and inflammatory markers in the Tsimane of Bolivia
Objectives: Little is known about blood cholesterol (blood‐C) levels under conditions of infection and limited diet. This study examines blood‐C and markers of infection and inflammation in the Tsimane of the Bolivian Amazon, indigenous forager farmers living in conditions that model preindustrial European populations by their short life expectancy, high load of infections and inflammation, and limited diets. Methods: We use multivariate models t…
Inflammatory Gene Variants in the Tsimane, an Indigenous Bolivian Population with a High Infectious Load
The Tsimane of lowland Bolivia are an indigenous forager-farmer population living under conditions resembling pre-industrial European populations, with high infectious morbidity, high infection and inflammation, and shortened life expectancy. Analysis of 917 persons ages 5 to 60+ showed that allele frequencies of 9 SNPs examined in the apolipoprotein E (apoE), C-reactive protein (CRP), and interleukin-6 (IL-6) genes differed from some European, A…
Exceptionally low mortality despite widespread Covid-19 infection among Indigenous Tsimane and Moseten of Bolivia
Medicine (7 works) · Demography (4 works) · Inflammation (4 works) · Population (4 works) · Biology (3 works) · Birth, Development, and Health (3 works) · Gerontology (3 works) · Immunology (3 works) · C-reactive protein (2 works) · Environmental health (2 works)